Summary

A0A1B0GUS0

Homolog: O70601.
Function: Linker for activation of T-cells family member 1.

Statistics

Total GO Annotation: 181
Unique PROST Go: 181
Unique BLAST Go: 0

Total Homologs: 89
Unique PROST Homologs: 88
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was O70601 (Linker for activation of T-cells family member 1) with a FATCAT P-Value: 0.0103 and RMSD of 4.44 angstrom. The sequence alignment identity is 21.6%.
Structural alignment shown in left. Query protein A0A1B0GUS0 colored as red in alignment, homolog O70601 colored as blue. Query protein A0A1B0GUS0 is also shown in right top, homolog O70601 showed in right bottom. They are colored based on secondary structures. 

  A0A1B0GUS0 MHPGVPEGPGVSEP---G----P------RELC-------AFVSGAAAHMLRALQPRR--TRPPKRRPNHRRFLHNQICRQFTKIEAATQRLALSILSQE 78
      O70601 ----M-EADALS-PVELGLLLLPFVVMLLAALCVRCRELPASYDSAST---ESLYPRSILIKPP------------QITVPRT---PAT---SYPLVTS- 72

  A0A1B0GUS0 APPQR-PSLQKPPPPPPSPFLGVACAVAPTEAPHASASLSLAALDT-----STLDLF---DNIALTPE--CASMPWD--PSS---GSDAPLPAPGLSHRD 162
      O70601 FPPLRQPDLL-PIPRSPQP-LG-GSHRMPSSRQNSDDANSVASYENQEPARKNVDEDEDEDDY---PEGYLVVLP-DSSPAAVPVVSSAPVP----SNPD 161

  A0A1B0GUS0 LGQLDLRQVPHF----C-GPLPLPQHALGEEADLVAPDWG---WV----DCWEVPRAWDSQGIPEGWGTSSP------------------------ 222
      O70601 LG--D----SAFSMESCEDYVNVPESEESAEASL---D-GSREYVNVSQDAQPVIRA-ELASV-----TSQEVEDEEEEDVDGEEAPDYENLQELN 241

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0001708 cell fate specification
2. P GO:0010508 positive regulation of autophagy
2. P GO:0021978 telencephalon regionalization
2. P GO:0048653 anther development
2. P GO:0070670 response to interleukin-4
2. P GO:0048542 lymph gland development
2. P GO:0080092 regulation of pollen tube growth
2. P GO:0000976 transcription cis-regulatory region binding
2. P GO:0055046 microgametogenesis
2. P GO:0001556 oocyte maturation
2. P GO:0007127 meiosis I
2. P GO:0008286 insulin receptor signaling pathway
2. P GO:0030901 midbrain development
2. P GO:2000543 positive regulation of gastrulation
2. P GO:0001547 antral ovarian follicle growth
2. P GO:0070542 response to fatty acid
2. P GO:0001819 positive regulation of cytokine production
2. P GO:0048872 homeostasis of number of cells
2. P GO:0030991 intraciliary transport particle A
2. P GO:0007265 Ras protein signal transduction
2. P GO:0031490 chromatin DNA binding
2. P GO:0031032 actomyosin structure organization
2. P GO:0008180 COP9 signalosome
2. P GO:0048096
2. P GO:2000177 regulation of neural precursor cell proliferation
2. P GO:0046627 negative regulation of insulin receptor signaling pathway
2. P GO:0050693 LBD domain binding
2. P GO:0035206 regulation of hemocyte proliferation
2. P GO:0031274 positive regulation of pseudopodium assembly
2. P GO:0012505 endomembrane system
2. P GO:0010888 negative regulation of lipid storage
2. P GO:0070345 negative regulation of fat cell proliferation
2. P GO:0010468 regulation of gene expression
2. P GO:0005929 cilium
2. P GO:1990641 response to iron ion starvation
2. P GO:1990846 ribonucleoside-diphosphate reductase inhibitor activity
2. P GO:0030838 positive regulation of actin filament polymerization
2. P GO:1990785 response to water-immersion restraint stress
2. P GO:0071104 response to interleukin-9
2. P GO:0007266 Rho protein signal transduction
2. P GO:0046620 regulation of organ growth
2. P GO:0043565 sequence-specific DNA binding
2. P GO:0045860 positive regulation of protein kinase activity
2. P GO:0048235 pollen sperm cell differentiation
2. P GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress
2. P GO:0045792 negative regulation of cell size
2. P GO:0071105 response to interleukin-11
2. P GO:1904646 cellular response to amyloid-beta
2. P GO:0048226 Casparian strip
2. P GO:0048640 negative regulation of developmental growth
2. P GO:0030336 negative regulation of cell migration
2. P GO:0017124 SH3 domain binding
2. P GO:0010582 floral meristem determinacy
2. P GO:1990019 protein storage vacuole organization
2. P GO:0042594 response to starvation
2. P GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
2. P GO:1990532 stress response to nickel ion
2. P GO:0006390 mitochondrial transcription
2. P GO:0030308 negative regulation of cell growth
2. P GO:0048854 brain morphogenesis
2. P GO:0019901 protein kinase binding
2. P GO:0002260 lymphocyte homeostasis
2. P GO:0019722 calcium-mediated signaling
2. P GO:2000253 positive regulation of feeding behavior
2. P GO:2000130 positive regulation of octopamine signaling pathway
2. P GO:0035721 intraciliary retrograde transport
2. P GO:0001542 ovulation from ovarian follicle
2. P GO:0042706 eye photoreceptor cell fate commitment
2. P GO:1903428 positive regulation of reactive oxygen species biosynthetic process
2. P GO:0036099 female germ-line stem cell population maintenance
2. P GO:1990090 cellular response to nerve growth factor stimulus
2. P GO:0048852 diencephalon morphogenesis
2. P GO:0071542 dopaminergic neuron differentiation
2. P GO:0055065 metal ion homeostasis
2. P GO:0010259 multicellular organism aging
2. P GO:0030330 DNA damage response, signal transduction by p53 class mediator
2. P GO:0010102 lateral root morphogenesis
2. P GO:0048658 anther wall tapetum development
2. P GO:0006355 regulation of transcription, DNA-templated
2. P GO:0009733 response to auxin
2. P GO:0005856 cytoskeleton
2. P GO:0052545 callose localization
2. P GO:0010432 bract development
2. P GO:0048655 anther wall tapetum morphogenesis
2. P GO:0048664 neuron fate determination
2. P GO:0022037 metencephalon development
2. P GO:1900386 positive regulation of flavonol biosynthetic process
2. P GO:0034599 cellular response to oxidative stress
2. P GO:0007568 aging
2. P GO:0006986 response to unfolded protein
2. P GO:0009416 response to light stimulus
2. P GO:0042149 cellular response to glucose starvation
2. P GO:0030159 signaling receptor complex adaptor activity
2. P GO:0007229 integrin-mediated signaling pathway
2. P GO:0060711 labyrinthine layer development
2. P GO:0070741 response to interleukin-6
2. P GO:0097150 neuronal stem cell population maintenance
2. P GO:1902462 positive regulation of mesenchymal stem cell proliferation
2. P GO:0000578 embryonic axis specification
2. P GO:0070669 response to interleukin-2
2. P GO:0003713 transcription coactivator activity
2. P GO:0010898 positive regulation of triglyceride catabolic process
2. P GO:0071559 response to transforming growth factor beta
2. P GO:0008285 negative regulation of cell population proliferation
2. P GO:0042641 actomyosin
2. P GO:0080166 stomium development
2. P GO:0031423 hexon binding
2. P GO:0034096 positive regulation of maintenance of meiotic sister chromatid cohesion
2. P GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
2. P GO:0033209 tumor necrosis factor-mediated signaling pathway
2. P GO:1901332 negative regulation of lateral root development
2. P GO:0003700 DNA-binding transcription factor activity
2. P GO:0010451 floral meristem growth
2. P GO:0051365 cellular response to potassium ion starvation
2. P GO:0043303 mast cell degranulation
2. P GO:0010597 green leaf volatile biosynthetic process
2. P GO:0050863 regulation of T cell activation
2. P GO:2000711 positive regulation of maintenance of meiotic sister chromatid cohesion, centromeric
2. P GO:2000067 regulation of root morphogenesis
2. P GO:0005634 nucleus
2. P GO:0099402 plant organ development
2. P GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand
2. P GO:0043525 positive regulation of neuron apoptotic process
2. P GO:0048382 mesendoderm development
2. P GO:0042593 glucose homeostasis
2. P GO:0000785 chromatin
2. P GO:0001772 immunological synapse
2. P GO:0001221 transcription coregulator binding
2. P GO:0071548 response to dexamethasone
2. P GO:0060712 spongiotrophoblast layer development
2. P GO:0070410 co-SMAD binding
2. P GO:0009994 oocyte differentiation
2. P GO:2000353 positive regulation of endothelial cell apoptotic process
2. P GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
2. P GO:0014737 positive regulation of muscle atrophy
2. P GO:0090009 primitive streak formation
2. P GO:0010467 gene expression
2. P GO:0061965 positive regulation of entry into reproductive diapause
2. P GO:0040036 regulation of fibroblast growth factor receptor signaling pathway
2. P GO:0030154 cell differentiation
2. P GO:0006357 regulation of transcription by RNA polymerase II
2. P GO:0009866 induced systemic resistance, ethylene mediated signaling pathway
2. P GO:0140463 chromatin-protein adaptor
2. P GO:0008190 eukaryotic initiation factor 4E binding
2. P GO:0009908 flower development
2. P GO:0034246 mitochondrial transcription factor activity
2. P GO:0001100 negative regulation of exit from mitosis
2. P GO:1990837 sequence-specific double-stranded DNA binding
2. P GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
2. P GO:0045665 negative regulation of neuron differentiation
2. P GO:0060231 mesenchymal to epithelial transition
2. P GO:1905117 regulation of ribonucleoside-diphosphate reductase activity
2. P GO:0071107 response to parathyroid hormone
2. P GO:0001544 initiation of primordial ovarian follicle growth
2. P GO:0060271 cilium assembly
2. P GO:1902895 positive regulation of miRNA transcription
2. P GO:0090506 axillary shoot meristem initiation
2. P GO:2000816 negative regulation of mitotic sister chromatid separation
2. P GO:0051276 chromosome organization
2. P GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
2. P GO:0045648 positive regulation of erythrocyte differentiation
2. P GO:0045143 homologous chromosome segregation
2. P GO:0051151 negative regulation of smooth muscle cell differentiation
2. P GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death
2. P GO:0070317 negative regulation of G0 to G1 transition
2. P GO:0071386 cellular response to corticosterone stimulus
2. P GO:0040019 positive regulation of embryonic development
2. P GO:0010224 response to UV-B
2. P GO:0051555 flavonol biosynthetic process
2. P GO:0019216 regulation of lipid metabolic process
2. P GO:0048533 sporocyte differentiation
2. P GO:0032525 somite rostral/caudal axis specification
2. P GO:0045944 positive regulation of transcription by RNA polymerase II
2. P GO:0010674 negative regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle
2. P GO:0030900 forebrain development
2. P GO:0045893 positive regulation of transcription, DNA-templated
2. P GO:0048366 leaf development
2. P GO:2000032 regulation of secondary shoot formation
2. P GO:0008013 beta-catenin binding
2. P GO:1990359 stress response to zinc ion
2. P GO:0071333 cellular response to glucose stimulus

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB A0A1B0GUS0 Uncharacterized protein C19orf85 0 1.78e-159 1.17e-158
2. P Q9FR97 Transcription factor MYB65 4.69e-01 3.38e-04 NA
2. P O54957 Linker for activation of T-cells family member 1 1.27e-02 8.01e-03 NA
2. P Q9ERC3 SERTA domain-containing protein 3 2.04e-02 6.27e-15 NA
2. P A6NEQ2 Protein FAM181B 7.45e-02 7.43e-06 NA
2. P Q9S773 Transcription factor MYB97 2.25e-01 7.30e-03 NA
2. P Q9SGU3 Transcription factor MYB72 2.37e-01 1.32e-04 NA
2. P A7MB34 Protein FAM181B 4.03e-02 2.49e-14 NA
2. P Q80VF6 Protein FAM181B 8.94e-02 4.54e-10 NA
2. P B3LYS5 Forkhead box protein O 4.68e-01 1.85e-03 NA
2. P P48568 Uncharacterized protein YDL186W 1.45e-01 8.43e-03 NA
2. P Q95V55 Forkhead box protein O 6.42e-01 1.29e-02 NA
2. P Q9JJG5 SERTA domain-containing protein 2 8.95e-02 1.01e-07 NA
2. P Q2M2T8 Uncharacterized protein C1orf185 homolog 4.32e-02 8.09e-03 NA
2. P Q6IUP1 Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1 5.89e-02 1.00e-06 NA
2. P Q91813 Homeobox protein OTX2-A 2.95e-02 1.09e-02 NA
2. P A8MZ59 Paired-like homeodomain transcription factor LEUTX 7.36e-02 8.09e-03 NA
2. P P80206 Homeobox protein OTX2 7.56e-02 4.04e-02 NA
2. P A0JM83 UPF0688 protein C1orf174 homolog 2.88e-01 1.11e-03 NA
2. P P38243 Uncharacterized protein YBR071W 1.87e-01 9.53e-03 NA
2. P O22264 Transcription factor MYB12 1.37e-01 9.72e-04 NA
2. P B4NFR1 Forkhead box protein O 2.53e-01 1.09e-02 NA
2. P E7F555 Intraflagellar transport protein 43 homolog 6.42e-01 6.71e-05 NA
2. P Q9NZH5 Securin-2 3.10e-01 8.16e-04 NA
2. P P32243 Homeobox protein OTX2 5.46e-02 4.08e-02 NA
2. P Q01663 AP-1-like transcription factor 1.17e-01 3.26e-02 NA
2. P Q6DKN2 Homeobox protein OTX2-B 2.76e-02 3.04e-02 NA
2. P Q17QW1 Cdc42 effector protein 1 1.91e-01 2.38e-02 NA
2. P Q6J9Q2 Ethylene-responsive transcription factor ERF086 3.09e-01 1.34e-02 NA
2. P P80073 Myb-related protein Pp2 2.76e-01 2.35e-02 NA
2. P P21455 28.1 kDa virulence protein 4.46e-01 4.59e-03 NA
2. P Q8LDR0 Dof zinc finger protein DOF5.4 3.38e-01 7.16e-03 NA
2. P Q4QR87 Doublesex- and mab-3-related transcription factor C1 6.80e-02 4.41e-02 NA
2. P Q9LJG6 Protein PATRONUS 1 3.12e-01 9.43e-03 NA
2. P Q2TBN9 Intraflagellar transport protein 43 homolog 1.02e-01 1.01e-02 NA
2. P A2T767 Securin NA 6.33e-05 NA
2. P Q9M2Y9 Transcription factor RAX3 9.32e-02 2.78e-02 NA
2. P Q756Z2 Damage-regulated import facilitator 1 5.77e-02 9.34e-03 NA
2. P B4JSC2 Forkhead box protein O 3.66e-01 8.16e-04 NA
2. P Q8IW50 Protein FAM219A 9.00e-02 3.12e-03 NA
2. P A6NMA1 Putative uncharacterized protein TRPC5OS 1.88e-02 1.69e-02 NA
2. P A4DA05 Xanthocillin biosynthesis cluster transcription factor xanC 3.85e-02 2.27e-03 NA
2. P O70601 Linker for activation of T-cells family member 1 1.03e-02 5.14e-03 NA
2. P P41546 Transcriptional activator HAC1 2.41e-02 2.47e-08 NA
2. P O97177 Enhancer of split M2 protein 2.00e-01 3.63e-02 NA
2. P Q14140 SERTA domain-containing protein 2 5.57e-02 6.76e-07 NA
2. P O43524 Forkhead box protein O3 3.51e-01 2.98e-02 NA
2. P Q298W7 Forkhead box protein O 2.99e-01 7.85e-03 NA
2. P Q9LSI7 Transcription factor MYB35 1.39e-01 9.63e-03 NA
2. P Q9D6I9 Leucine rich adaptor protein 1 3.02e-02 3.08e-03 NA
2. P P40316 Securin 1.58e-01 1.11e-02 NA
2. P Q8TFU8 Transcriptional activator hacA 1.16e-02 7.53e-05 NA
2. P O81836 Protein SPOROCYTELESS 1.37e-01 1.74e-04 NA
2. P O13859 Meiotically up-regulated gene 125 protein 3.97e-01 3.18e-03 NA
2. P Q9BGQ5 Protein FAM219A 5.62e-01 3.85e-02 NA
2. P Q9FKL2 Transcription factor MYB36 2.07e-01 1.43e-03 NA
2. P Q6NZY7 Cdc42 effector protein 5 1.59e-01 2.23e-04 NA
2. P Q9BXL8 Cell division cycle-associated protein 4 7.58e-02 8.43e-04 NA
2. P B3P0K6 Forkhead box protein O 4.53e-01 5.36e-03 NA
2. P Q5UPC6 Uncharacterized protein L46 NA 1.31e-05 NA
2. P Q99966 Cbp/p300-interacting transactivator 1 3.71e-01 1.17e-02 NA
2. P P33306 Protein BCK2 7.75e-01 2.57e-07 NA
2. P D4A8G3 Leucine rich adaptor protein 1 1.06e-01 5.25e-03 NA
2. P B4HF64 Forkhead box protein O 4.93e-01 4.49e-02 NA
2. P Q6IDB0 Protein SPEAR3 2.12e-01 1.49e-02 NA
2. P Q9WVH4 Forkhead box protein O3 3.89e-01 5.65e-03 NA
2. P P45815 Copper resistance protein CRF1 6.77e-02 4.45e-02 NA
2. P Q9UJW9 SERTA domain-containing protein 3 7.66e-02 1.94e-14 NA
2. P Q91W92 Cdc42 effector protein 1 1.12e-01 6.78e-04 NA
2. P Q9CWM2 Cell division cycle-associated protein 4 2.61e-02 7.85e-08 NA
2. P Q50EX6 MYB-like transcription factor ODO1 5.89e-01 1.89e-02 NA
2. P Q9MAH8 Transcription factor TCP3 1.53e-01 2.76e-02 NA
2. P Q84X40 Protein SPEAR1 2.17e-01 2.98e-02 NA
2. P Q9LZK4 Transcription factor MYB11 1.68e-01 6.87e-03 NA
2. P A1YF19 Securin 2.38e-01 1.12e-03 NA
2. P B4G4S8 Forkhead box protein O 4.02e-01 2.70e-02 NA
2. P A0A1U9YI06 Transcription factor verZ 2.65e-01 2.92e-04 NA
2. P Q9UHV2 SERTA domain-containing protein 1 6.57e-02 1.71e-10 NA
2. P Q96S65 Cysteine/serine-rich nuclear protein 1 3.97e-01 4.32e-02 NA
2. P Q64846 Pre-hexon-linking protein VIII NA 1.20e-02 NA
2. P Q1XGE2 Transcriptional activator hacA 1.57e-02 3.65e-04 NA
2. P Q9JL10 SERTA domain-containing protein 1 4.89e-02 9.75e-09 NA
2. P Q9SB92 Protein WUSCHEL 4.69e-02 1.13e-02 NA
2. P Q84VT7 Protein WUSCHEL 4.10e-02 3.96e-02 NA
2. P Q6EUW1 Forkhead box protein O3 6.03e-01 2.87e-02 NA
2. P Q9WVH3 Forkhead box protein O4 4.88e-01 2.01e-04 NA
2. P O95997 Securin 2.22e-01 2.47e-04 NA
2. P F4JSU0 Transcription factor MYB87 1.14e-01 5.65e-03 NA
2. P B5G1P1 Intraflagellar transport protein 43 homolog 5.80e-02 6.59e-03 NA