Summary

A6NC05

Homolog: Q56108.
Function: Glutaredoxin-like protein NrdH.

Statistics

Total GO Annotation: 61
Unique PROST Go: 60
Unique BLAST Go: 0

Total Homologs: 102
Unique PROST Homologs: 100
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was Q56108 (Glutaredoxin-like protein NrdH) with a FATCAT P-Value: 0.00975 and RMSD of 1.18 angstrom. The sequence alignment identity is 17.3%.
Structural alignment shown in left. Query protein A6NC05 colored as red in alignment, homolog Q56108 colored as blue. Query protein A6NC05 is also shown in right top, homolog Q56108 showed in right bottom. They are colored based on secondary structures. 

  A6NC05 MLWFQGNSMQLARSSFGLFLRNCSASKTTLPV-LTLFTKDPCPLCDEAKEVL--KPYENRQPYKDQKLP---GTRRRRSPSSPSHPHMASQSGKRYNLTL 94
  Q56108 -------------------------------MSITIYTRNNCVQCHATKRAMESRGFEFEMVNVDL-VPDAADTLR-------------AQ-GFR-QLPV 53

  A6NC05 NQVLSFDYDMGLDAPKTIS-SDCGAFYCLRMFKSPDMTCCFYPKQ----- 138
  Q56108 --VMA-----G-D----LSWS--G-F---R----PDMINRLHPTPHAANA 81

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
1. PB GO:0005739 mitochondrion
2. P GO:1990748 cellular detoxification
2. P GO:0106034 protein maturation by [2Fe-2S] cluster transfer
2. P GO:0106035 protein maturation by [4Fe-4S] cluster transfer
2. P GO:0042246 tissue regeneration
2. P GO:0008794 arsenate reductase (glutaredoxin) activity
2. P GO:0009853 photorespiration
2. P GO:0010033 response to organic substance
2. P GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity
2. P GO:0005747 mitochondrial respiratory chain complex I
2. P GO:0016992 lipoate synthase activity
2. P GO:0102553 lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)
2. P GO:0005762 mitochondrial large ribosomal subunit
2. P GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation
2. P GO:0006450 regulation of translational fidelity
2. P GO:0004362 glutathione-disulfide reductase (NADPH) activity
2. P GO:0015035 protein-disulfide reductase activity
2. P GO:0007623 circadian rhythm
2. P GO:0044571 [2Fe-2S] cluster assembly
2. P GO:0030097 hemopoiesis
2. P GO:0005743 mitochondrial inner membrane
2. P GO:0031966 mitochondrial membrane
2. P GO:0009507 chloroplast
2. P GO:0002162 dystroglycan binding
2. P GO:0009863 salicylic acid mediated signaling pathway
2. P GO:0017087 mitochondrial processing peptidase complex
2. P GO:0043025 neuronal cell body
2. P GO:0006627 protein processing involved in protein targeting to mitochondrion
2. P GO:0005761 mitochondrial ribosome
2. P GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity
2. P GO:0019253 reductive pentose-phosphate cycle
2. P GO:0042262 DNA protection
2. P GO:0061133 endopeptidase activator activity
2. P GO:0071451 cellular response to superoxide
2. P GO:0005759 mitochondrial matrix
2. P GO:0042542 response to hydrogen peroxide
2. P GO:0030425 dendrite
2. P GO:0046872 metal ion binding
2. P GO:0032543 mitochondrial translation
2. P GO:0051537 2 iron, 2 sulfur cluster binding
2. P GO:0001835 blastocyst hatching
2. P GO:0000137 Golgi cis cisterna
2. P GO:0097573 glutathione oxidoreductase activity
2. P GO:0010811 positive regulation of cell-substrate adhesion
2. P GO:0036455 iron-sulfur transferase activity
2. P GO:0015036 disulfide oxidoreductase activity
2. P GO:0015038 glutathione disulfide oxidoreductase activity
2. P GO:0034599 cellular response to oxidative stress
2. P GO:0045454 cell redox homeostasis
2. P GO:0102552 lipoyl synthase activity (acting on glycine-cleavage complex H protein
2. P GO:0042326 negative regulation of phosphorylation
2. P GO:0044572 [4Fe-4S] cluster assembly
2. P GO:0007568 aging
2. P GO:0016491 oxidoreductase activity
2. P GO:0010287 plastoglobule
2. P GO:0042776 mitochondrial ATP synthesis coupled proton transport
2. P GO:0009266 response to temperature stimulus
2. P GO:0032981 mitochondrial respiratory chain complex I assembly
2. P GO:0009867 jasmonic acid mediated signaling pathway
2. P GO:0000002 mitochondrial genome maintenance
2. P GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB A6NC05 Glutaredoxin-like protein C5orf63 0 9.38e-133 1.06e-100
1. PB Q9CWB7 Glutaredoxin-like protein C5orf63 homolog 4.77e-02 5.07e-23 2.93e-24
2. P Q5UQ14 Probable glutaredoxin NA 2.45e-03 NA
2. P Q9FVX1 Glutaredoxin-C3 2.03e-01 3.09e-06 NA
2. P P38231 Protein FMP23, mitochondrial 6.53e-01 1.61e-02 NA
2. P Q9NQ50 39S ribosomal protein L40, mitochondrial 4.40e-01 3.81e-02 NA
2. P Q4RSW7 Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial 2.51e-01 3.52e-03 NA
2. P P16136 Ribulose bisphosphate carboxylase small subunit, chloroplastic 3 5.36e-01 3.33e-02 NA
2. P Q6PBM1 Glutaredoxin-related protein 5, mitochondrial 1.98e-01 5.87e-07 NA
2. P Q05266 Gene 56 protein NA 1.61e-04 NA
2. P Q05530 Glutaredoxin-like protein YDR286C 7.56e-02 3.50e-16 NA
2. P Q09774 ATP synthase subunit g, mitochondrial 1.84e-01 4.24e-02 NA
2. P Q9Y6G3 39S ribosomal protein L42, mitochondrial 4.09e-01 1.78e-02 NA
2. P O94504 Thioredoxin-2, mitochondrial 1.01e-01 3.46e-03 NA
2. P C5GPL2 Lipoyl synthase, mitochondrial 7.35e-01 4.31e-02 NA
2. P Q02784 Monothiol glutaredoxin-5, mitochondrial 1.56e-01 4.88e-09 NA
2. P P64728 Uncharacterized protein Mb0520 7.73e-02 2.27e-03 NA
2. P P68691 Glutaredoxin-1 NA 3.49e-02 NA
2. P P9WKS9 Uncharacterized protein Rv0508 3.85e-02 2.27e-03 NA
2. P Q0MQ92 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 2.03e-01 2.54e-08 NA
2. P Q923X4 Glutaredoxin-2, mitochondrial 3.62e-01 3.84e-03 NA
2. P Q8GWS0 Glutaredoxin-C5, chloroplastic 2.06e-01 7.15e-06 NA
2. P Q17424 Probable thioredoxin-2 9.96e-02 3.90e-05 NA
2. P Q0JQ97 Monothiol glutaredoxin-S1, mitochondrial 1.97e-01 2.19e-02 NA
2. P Q9FIJ2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 1.81e-01 5.01e-06 NA
2. P Q8SUM8 Glutaredoxin-like protein ECU08_1380 9.39e-02 4.08e-04 NA
2. P P23955 Mitochondrial-processing peptidase subunit alpha 8.29e-01 1.78e-02 NA
2. P Q555C8 Monothiol glutaredoxin-5, mitochondrial 8.22e-02 6.51e-08 NA
2. P Q7U8R4 Circadian clock protein KaiB 9.83e-02 1.57e-02 NA
2. P P36141 Putative redox protein FMP46, mitochondrial 2.41e-01 8.08e-09 NA
2. P Q758S3 54S ribosomal protein L51, mitochondrial 1.87e-01 6.43e-08 NA
2. P Q99N89 39S ribosomal protein L43, mitochondrial 3.06e-01 2.40e-02 NA
2. P Q79V61 Circadian clock protein KaiB 1.16e-01 4.34e-03 NA
2. P Q75EB9 Genetic interactor of prohibitin 7, mitochondrial 4.60e-01 1.81e-02 NA
2. P Q06090 54S ribosomal protein L51, mitochondrial 1.90e-01 1.02e-05 NA
2. P Q9HDW8 Monothiol glutaredoxin-5, mitochondrial 1.80e-01 5.11e-08 NA
2. P C7GJ54 Inner membrane assembly complex subunit 17 4.96e-01 4.20e-02 NA
2. P P04714 Ribulose bisphosphate carboxylase small subunit, chloroplastic 1 6.14e-01 1.71e-02 NA
2. P C5JVC1 Lipoyl synthase, mitochondrial 7.99e-01 4.31e-02 NA
2. P Q54EX7 Glutaredoxin-like protein 2.61e-01 4.55e-03 NA
2. P Q56108 Glutaredoxin-like protein NrdH 9.75e-03 2.72e-02 NA
2. P Q54N68 Glutaredoxin-like protein YDR286C homolog 3.36e-02 1.10e-05 NA
2. P Q7ZZH4 Anterior gradient protein 2-B 2.58e-01 3.36e-02 NA
2. P P68690 Glutaredoxin-1 NA 3.49e-02 NA
2. P P0CB79 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 2.10e-01 7.44e-08 NA
2. P Q80Y14 Glutaredoxin-related protein 5, mitochondrial 1.78e-01 6.77e-06 NA
2. P Q0J3L4 Monothiol glutaredoxin-S10 2.03e-01 2.75e-03 NA
2. P Q9SGP6 Glutaredoxin-C9 3.84e-01 1.23e-02 NA
2. P Q86SX6 Glutaredoxin-related protein 5, mitochondrial 3.23e-01 2.33e-04 NA
2. P Q8LBK6 Monothiol glutaredoxin-S15, mitochondrial 1.35e-01 1.61e-02 NA
2. P Q3MEE5 Circadian clock protein KaiB 6.76e-02 1.51e-02 NA
2. P Q9SSR1 DCC family protein At1g52590, chloroplastic 2.98e-01 1.09e-04 NA
2. P Q07842 NADH-ubiquinone oxidoreductase 10.5 kDa subunit 1.54e-01 1.15e-03 NA
2. P P16132 Ribulose bisphosphate carboxylase small subunit, chloroplastic 4 5.35e-01 8.69e-03 NA
2. P P9WKS8 Uncharacterized protein MT0529 3.92e-02 2.27e-03 NA
2. P Q32L67 Glutaredoxin-2, mitochondrial 1.88e-01 3.27e-06 NA
2. P Q90Y05 Anterior gradient protein 2-A 2.40e-01 3.74e-02 NA
2. P A6RDX3 54S ribosomal protein L4, mitochondrial 5.68e-01 2.23e-02 NA
2. P Q9NS18 Glutaredoxin-2, mitochondrial 1.17e-01 3.84e-04 NA
2. P Q44856 Disulfide bond formation protein 7.42e-02 2.53e-02 NA
2. P B5DK05 Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial 3.21e-01 4.92e-02 NA
2. P Q0DAE4 Glutaredoxin-C8 6.73e-02 2.27e-09 NA
2. P O48646 Probable phospholipid hydroperoxide glutathione peroxidase 6, mitochondrial 5.18e-01 3.52e-02 NA
2. P Q8YT41 Circadian clock protein KaiB 1.09e-01 1.25e-02 NA
2. P Q6RZN3 Glutaredoxin-1 NA 3.49e-02 NA
2. P Q4R5E2 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 2.02e-01 4.41e-08 NA
2. P Q19297 Uncharacterized monothiol glutaredoxin F10D7.3 2.78e-01 8.44e-06 NA
2. P Q77TL9 Glutaredoxin-1 NA 3.49e-02 NA
2. P P68692 Glutaredoxin-1 NA 3.49e-02 NA
2. P Q8LBS4 Monothiol glutaredoxin-S12, chloroplastic 1.29e-01 1.14e-04 NA
2. P Q6YFE4 Monothiol glutaredoxin-5, mitochondrial 1.91e-01 2.71e-10 NA
2. P P0CB80 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 2.10e-01 7.44e-08 NA
2. P Q0JM76 Monothiol glutaredoxin-S4, mitochondrial 1.99e-01 4.29e-04 NA
2. P A2BHB7 Glutamyl-tRNA(Gln) amidotransferase subunit C, mitochondrial 3.69e-01 2.27e-02 NA
2. P Q02370 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 2.43e-01 1.13e-07 NA
2. P P74593 Probable glutaredoxin slr1562 1.14e-01 2.72e-02 NA
2. P Q6K953 Glutaredoxin-C4, chloroplastic 2.88e-01 4.31e-02 NA
2. P P16138 Ribulose bisphosphate carboxylase small subunit, chloroplastic 5 6.33e-01 4.03e-03 NA
2. P O43678 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 2.41e-01 2.60e-08 NA
2. P O34639 Putative glutaredoxin YtnI 3.05e-01 3.77e-03 NA
2. P Q9UUC8 54S ribosomal protein L51, mitochondrial 2.52e-01 5.60e-06 NA
2. P Q9XFI1 Thioredoxin-like 1-2, chloroplastic 3.02e-01 4.79e-02 NA
2. P Q6H628 Monothiol glutaredoxin-S6 2.77e-01 7.17e-08 NA
2. P Q9CQ75 NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 2.61e-01 1.81e-07 NA
2. P Q8W485 Uncharacterized protein At5g50100, chloroplastic 4.19e-01 1.75e-06 NA
2. P Q6AXW1 Glutaredoxin-2, mitochondrial 3.52e-01 9.43e-04 NA
2. P Q9VE04 39S ribosomal protein L55, mitochondrial 4.31e-01 1.83e-02 NA
2. P Q0U6J9 54S ribosomal protein L4, mitochondrial 5.10e-01 2.04e-02 NA
2. P Q8L9S3 Glutaredoxin-C6 3.12e-01 2.31e-03 NA
2. P Q6CN57 Putative redox protein FMP46, mitochondrial 3.09e-01 1.12e-08 NA
2. P P16137 Ribulose bisphosphate carboxylase small subunit, chloroplastic 4 4.74e-01 1.22e-04 NA
2. P P25372 Thioredoxin-3, mitochondrial 2.86e-01 1.98e-05 NA
2. P Q6FJI9 Putative redox protein FMP46, mitochondrial 2.18e-01 6.43e-08 NA
2. P O64263 Gene 70 protein NA 3.70e-03 NA
2. P Q76ZV3 Glutaredoxin-1 NA 3.49e-02 NA
2. P P18960 Ribulose bisphosphate carboxylase small subunit, chloroplastic 5.40e-01 2.51e-02 NA
2. P Q28ID5 Anterior gradient protein 2 3.01e-01 6.15e-03 NA
2. P Q5RC53 Glutaredoxin-2, mitochondrial 1.11e-01 1.04e-04 NA
2. P Q6L8K0 Circadian clock protein KaiB 1.30e-01 4.34e-03 NA
2. P Q04450 Ribulose bisphosphate carboxylase small subunit, chloroplastic 2 6.15e-01 1.64e-02 NA
2. P Q5A3J1 54S ribosomal protein L51, mitochondrial 1.55e-01 5.74e-07 NA
2. P Q8LFQ6 Glutaredoxin-C4 2.03e-01 4.98e-04 NA