Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PB was
A6NJQ4
(Putative protein FAM90A8P) with a FATCAT P-Value: 8.49e-12 and RMSD of 4.13 angstrom. The sequence alignment identity is 97.6%.
Structural alignment shown in left. Query protein A6NDY2 colored as red in alignment, homolog A6NJQ4 colored as blue.
Query protein A6NDY2 is also shown in right top, homolog A6NJQ4 showed in right bottom. They are colored based on secondary structures.
A6NDY2 MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTTCPMKCWKAALVPATLGKKEGKENLKPWKPRGEANPGPLNKDK 100 A6NJQ4 MMARRDPKSWAKRLVRAQTLQKQRRAPVGPSAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRGEANPGPLNKDK 100 A6NDY2 GEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSEHLRVASGPMPVHTTSKRPRVDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPK 200 A6NJQ4 GEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLGPK 200 A6NDY2 ERQTGAAADIPQPAFRHQGPEPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQA 300 A6NJQ4 ERQTGAAADIPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQA 300 A6NDY2 CLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDWQPPHSTPCLPTAQACTMSHHPAAGHDGAQPLRVLFRRLE 400 A6NJQ4 CLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSIDRQPPHSTPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLE 400 A6NDY2 NGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE 464 A6NJQ4 NGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE 464
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source | GO | Description |
---|---|---|
2. P | GO:0003682 | chromatin binding |
2. P | GO:0016973 | poly(A)+ mRNA export from nucleus |
2. P | GO:0006334 | nucleosome assembly |
2. P | GO:0007051 | spindle organization |
2. P | GO:1903863 | P granule assembly |
2. P | GO:0006333 | chromatin assembly or disassembly |
2. P | GO:0042995 | cell projection |
2. P | GO:0019901 | protein kinase binding |
2. P | GO:0010847 | regulation of chromatin assembly |
2. P | GO:0030849 | autosome |
2. P | GO:0006281 | DNA repair |
2. P | GO:0042393 | histone binding |
2. P | GO:0043486 | histone exchange |
2. P | GO:0003729 | mRNA binding |
2. P | GO:0031519 | PcG protein complex |
2. P | GO:0007141 | male meiosis I |
2. P | GO:0001042 | RNA polymerase I core binding |
2. P | GO:1905168 | positive regulation of double-strand break repair via homologous recombination |
2. P | GO:0005813 | centrosome |
2. P | GO:0005652 | nuclear lamina |
2. P | GO:0000792 | heterochromatin |
2. P | GO:0009792 | embryo development ending in birth or egg hatching |
2. P | GO:0051308 | male meiosis chromosome separation |
2. P | GO:0005634 | nucleus |
2. P | GO:0030870 | Mre11 complex |
2. P | GO:0006974 | cellular response to DNA damage stimulus |
2. P | GO:0010212 | response to ionizing radiation |
2. P | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining |
2. P | GO:0007095 | mitotic G2 DNA damage checkpoint signaling |
2. P | GO:0071168 | protein localization to chromatin |
2. P | GO:0007344 | pronuclear fusion |
2. P | GO:0006997 | nucleus organization |
2. P | GO:0003727 | single-stranded RNA binding |
2. P | GO:0045860 | positive regulation of protein kinase activity |
2. P | GO:0005654 | nucleoplasm |
2. P | GO:0006878 | cellular copper ion homeostasis |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
---|---|---|---|---|---|
1. PB | A8MXJ8 | Putative protein FAM90A5P | 1.51e-05 | 7.96e-91 | 0.0 |
1. PB | P0C7W9 | Putative protein FAM90A14P | 5.44e-07 | 1.37e-83 | 0.0 |
1. PB | P0C7V4 | Putative protein FAM90A15P | 4.83e-08 | 1.28e-80 | 0.0 |
1. PB | P0C7W8 | Putative protein FAM90A13P | 2.95e-07 | 7.95e-85 | 0.0 |
1. PB | A6NIJ5 | Putative protein FAM90A20P | 1.08e-05 | 2.22e-89 | 0.0 |
1. PB | A6NNJ1 | Putative protein FAM90A9P | 2.99e-08 | 8.91e-113 | 0.0 |
1. PB | A6NE21 | Putative protein FAM90A18P/FAM90A19P | 3.85e-09 | 6.81e-115 | 0.0 |
1. PB | Q86YD7 | Protein FAM90A1 | 5.02e-07 | 3.26e-66 | 0.0 |
1. PB | A6NEW6 | Putative protein FAM90A16P/FAM90A17P | 8.18e-07 | 3.41e-90 | 0.0 |
1. PB | A6NJQ4 | Putative protein FAM90A8P | 8.49e-12 | 7.89e-96 | 0.0 |
1. PB | D6RGX4 | Putative protein FAM90A26 | 2.10e-05 | 7.55e-82 | 0.0 |
1. PB | A8MWA6 | Putative protein FAM90A22P | 7.24e-10 | 6.11e-81 | 0.0 |
1. PB | A8MXZ1 | Putative protein FAM90A23P | 9.54e-10 | 1.29e-84 | 0.0 |
1. PB | P0C7X0 | Putative protein FAM90A24P | 1.03e-09 | 1.44e-86 | 0.0 |
1. PB | Q658T7 | Putative protein FAM90A2P | 2.58e-05 | 2.52e-47 | 0.0 |
1. PB | A8MX19 | Putative protein FAM90A12P | 5.24e-06 | 4.62e-93 | 0.0 |
1. PB | A6NNH2 | Protein FAM90A27P | 3.90e-03 | 1.21e-24 | 1.26e-41 |
1. PB | A6NDY2 | Putative protein FAM90A10P | 0 | 2.08e-146 | 0.0 |
1. PB | A6NKC0 | Putative protein FAM90A7P | 1.84e-10 | 2.62e-107 | 0.0 |
2. P | B4HMH2 | Protein teflon | 1.48e-01 | 4.08e-02 | NA |
2. P | Q6NZF1 | Zinc finger CCCH domain-containing protein 11A | 1.42e-01 | 2.95e-02 | NA |
2. P | Q8IMP6 | Protein SPT2 homolog | 4.50e-01 | 5.11e-05 | NA |
2. P | Q9D1F5 | MRN complex-interacting protein | 1.00e-01 | 8.28e-03 | NA |
2. P | Q5ZJJ1 | Zinc finger CCCH domain-containing protein 11A | 3.94e-01 | 1.57e-03 | NA |
2. P | P20129 | 70 kDa protein | NA | 7.58e-03 | NA |
2. P | Q5ZK13 | Centrosomal protein kizuna | 5.38e-02 | 6.75e-06 | NA |
2. P | Q2M2Z5 | Centrosomal protein kizuna | 1.10e-01 | 6.74e-05 | NA |
2. P | Q8C3W1 | Uncharacterized protein C1orf198 homolog | 4.82e-01 | 1.48e-02 | NA |
2. P | P25028 | Mitosis initiation protein fs(1)Ya | 2.02e-01 | 1.49e-02 | NA |
2. P | D3YT16 | Enlarged germline granules protein 1 | 2.78e-01 | 5.45e-04 | NA |
2. P | O75152 | Zinc finger CCCH domain-containing protein 11A | 2.35e-01 | 1.77e-02 | NA |
2. P | A0A1B0GTU1 | Zinc finger CCCH domain-containing protein 11B | 3.73e-01 | 5.22e-03 | NA |
2. P | Q6DGN6 | Protein SPT2 homolog | 9.45e-02 | 2.71e-03 | NA |
2. P | Q3ZBG8 | MRN complex-interacting protein | 5.97e-02 | 2.93e-03 | NA |
2. P | Q92258 | Protein GRISEA | 1.97e-01 | 2.02e-02 | NA |
2. P | Q5REG6 | Zinc finger CCCH domain-containing protein 11A | 3.05e-01 | 3.30e-02 | NA |
2. P | Q9DBY5 | Chromobox protein homolog 6 | 9.10e-02 | 4.08e-02 | NA |
2. P | Q6NTE8 | MRN complex-interacting protein | 3.48e-01 | 1.06e-04 | NA |
2. P | Q3UXL4 | Centrosomal protein kizuna | 3.38e-01 | 3.24e-03 | NA |
2. P | Q32PP1 | MRN complex-interacting protein | 8.65e-02 | 2.18e-02 | NA |