Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PB was
Q6ZRT6
(Proline-rich protein 23B) with a FATCAT P-Value: 1.04e-09 and RMSD of 2.68 angstrom. The sequence alignment identity is 89.9%.
Structural alignment shown in left. Query protein A6NEV1 colored as red in alignment, homolog Q6ZRT6 colored as blue.
Query protein A6NEV1 is also shown in right top, homolog Q6ZRT6 showed in right bottom. They are colored based on secondary structures.
A6NEV1 MGSRPRSPSAFPAPWWGQQPGGPGPAKRLRLEEPAGPEPRVAPSLEDPAGTPAVGALTSIVVLAAGCALRVPLDDVDLVLELP-PTSILRVSLDGHTLIL 99 Q6ZRT6 MVSRPRSPSAFPAPWWGQQPGGPGPAKRLRLEEPAGPEPRAAPSLEDPAGDPAVDALTSIVVLAAGCALRVPLDDVDLVLE-PAPTSILRVSLGGHTLIL 99 A6NEV1 IPEVLLSSVDERSGAQDDSSAGLEVDVFLGALREDVVVEQEVFCASVPEIAAQEEAYEEDADPEFPELQMDSAAGSAAGLYSSARSMFSPYREGPIPEPC 199 Q6ZRT6 IPEVLLSSVDERSGAQHDSSAGLEVDVFLGAVREDVVVELE-FCASVPEIAAQEEAYEEDADPEFPELRMDSPTGSAAGLYPSSRSMFIPYREGPIPEPC 198 A6NEV1 ALAPNPSSEGHSPGPFFDPEFRLLEPVPSSPLQPLPPSPRVGSPGPHAHPPLPKRPPCKARRRLFQE 266 Q6ZRT6 ALAPNPSSERRSPRPIFDLEFRLLEPVPSSPLQPLPPSPCVGSPGPHARSPLPERPPCKARRRLFQA 265
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source | GO | Description |
---|---|---|
2. P | GO:0031344 | regulation of cell projection organization |
2. P | GO:0001763 | morphogenesis of a branching structure |
2. P | GO:0051015 | actin filament binding |
2. P | GO:0007015 | actin filament organization |
2. P | GO:0030175 | filopodium |
2. P | GO:0043209 | myelin sheath |
2. P | GO:0005856 | cytoskeleton |
2. P | GO:0005938 | cell cortex |
2. P | GO:0043025 | neuronal cell body |
2. P | GO:0033269 | internode region of axon |
2. P | GO:0030308 | negative regulation of cell growth |
2. P | GO:0033270 | paranode region of axon |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
---|---|---|---|---|---|
1. PB | Q6ZRT6 | Proline-rich protein 23B | 1.04e-09 | 1.84e-69 | 9.74e-149 |
1. PB | Q9CWP9 | Proline-rich protein 23A3 | 5.67e-05 | 1.12e-30 | 3.07e-32 |
1. PB | A6NEV1 | Proline-rich protein 23A | 0 | 9.60e-170 | 0.0 |
1. PB | Q6ZRP0 | Proline-rich protein 23C | 4.96e-05 | 6.77e-43 | 1.83e-119 |
2. P | P0DMB1 | Proline-rich protein 23D2 | 3.57e-03 | 8.42e-10 | NA |
2. P | Q01030 | Uncharacterized gene 45 protein | NA | 3.39e-02 | NA |
2. P | Q9ERC3 | SERTA domain-containing protein 3 | 6.20e-01 | 2.94e-02 | NA |
2. P | Q5RJL0 | Ermin | 1.08e-01 | 1.31e-02 | NA |
2. P | E9PI22 | Proline-rich protein 23D1 | 1.67e-03 | 8.42e-10 | NA |
2. P | P0CAM4 | Uncharacterized protein D129L | NA | 2.22e-03 | NA |