Summary

A6NMA1

Homolog: Q07541.
Function: ER export of PMA1 protein 1.

Statistics

Total GO Annotation: 21
Unique PROST Go: 21
Unique BLAST Go: 0

Total Homologs: 17
Unique PROST Homologs: 15
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was Q07541 (ER export of PMA1 protein 1) with a FATCAT P-Value: 0.00565 and RMSD of 3.16 angstrom. The sequence alignment identity is 19.7%.
Structural alignment shown in left. Query protein A6NMA1 colored as red in alignment, homolog Q07541 colored as blue. Query protein A6NMA1 is also shown in right top, homolog Q07541 showed in right bottom. They are colored based on secondary structures. 

  A6NMA1 MD---SVLIHVLIDGLVACVAQLIRIADELLQFIL--------------QVQEVPYVEENGRAEET---EADAPLPE-EPSL-PDLPDLS------DLDS 72
  Q07541 MNLYGYFLL-LII--VIAFIA-LLPLFSGIGTFKLTKPKSSATAQSATGKLGKREYLKK--KLDHTNVLKFD--LKDTEESLGHDSASASSASRKFEIDS 92

  A6NMA1 --ILTPR------ED-EDLIFDIDQAMLDMDNLYEDTVSGIN-DDLTGD------------------------ 111
  Q07541 KTGLKRRVIGQYNKDPND--FDFD---ID-D-L-------INEDEL--DERREEEKKLKKYNGKKNEAYEGFV 149

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0030663 COPI-coated vesicle membrane
2. P GO:0048096
2. P GO:0012505 endomembrane system
2. P GO:0031274 positive regulation of pseudopodium assembly
2. P GO:0033644 host cell membrane
2. P GO:0005634 nucleus
2. P GO:0045842 positive regulation of mitotic metaphase/anaphase transition
2. P GO:0005680 anaphase-promoting complex
2. P GO:0006355 regulation of transcription, DNA-templated
2. P GO:0031145 anaphase-promoting complex-dependent catabolic process
2. P GO:0030308 negative regulation of cell growth
2. P GO:0012507 ER to Golgi transport vesicle membrane
2. P GO:1905785 negative regulation of anaphase-promoting complex-dependent catabolic process
2. P GO:0030838 positive regulation of actin filament polymerization
2. P GO:0045944 positive regulation of transcription by RNA polymerase II
2. P GO:0007254 JNK cascade
2. P GO:0045893 positive regulation of transcription, DNA-templated
2. P GO:0007266 Rho protein signal transduction
2. P GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
2. P GO:0031267 small GTPase binding
2. P GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q3UHV4 Putative uncharacterized protein TRPC5OS homolog 3.63e-04 5.82e-16 7.15e-28
1. PB A6NMA1 Putative uncharacterized protein TRPC5OS 0 3.06e-144 1.03e-72
2. P Q9UJW9 SERTA domain-containing protein 3 1.73e-02 2.68e-02 NA
2. P Q9ERC3 SERTA domain-containing protein 3 4.35e-02 1.28e-03 NA
2. P F1QY75 Anaphase-promoting complex subunit 15 1.03e-01 3.77e-02 NA
2. P C5DFL1 Damage-regulated import facilitator 1 2.33e-02 2.37e-02 NA
2. P P40141 Protein new-glue 4 1.28e-01 2.64e-03 NA
2. P A0A1B0GUS0 Uncharacterized protein C19orf85 1.26e-01 2.97e-02 NA
2. P Q9UHV2 SERTA domain-containing protein 1 2.47e-02 5.96e-04 NA
2. P P54587 Uncharacterized protein YhcC 4.07e-03 2.88e-02 NA
2. P Q9JL10 SERTA domain-containing protein 1 1.55e-01 1.84e-03 NA
2. P O94688 Anaphase-promoting complex subunit 15 6.77e-03 1.99e-03 NA
2. P Q66181 Non-structural protein 4 NA 4.70e-02 NA
2. P Q6NZY7 Cdc42 effector protein 5 2.98e-01 9.54e-03 NA
2. P O29215 Uncharacterized protein AF_1047 1.27e-02 1.13e-03 NA
2. P A0A1B0GUV1 Uncharacterized protein C17orf114 8.79e-02 4.10e-02 NA
2. P Q07541 ER export of PMA1 protein 1 5.65e-03 5.43e-03 NA