Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PB was
P0C7X0
(Putative protein FAM90A24P) with a FATCAT P-Value: 1.65e-09 and RMSD of 5.79 angstrom. The sequence alignment identity is 97.6%.
Structural alignment shown in left. Query protein A6NNJ1 colored as red in alignment, homolog P0C7X0 colored as blue.
Query protein A6NNJ1 is also shown in right top, homolog P0C7X0 showed in right bottom. They are colored based on secondary structures.
A6NNJ1 MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDK 100 P0C7X0 MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRGEANPGPLNKDK 100 A6NNJ1 GEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLGPK 200 P0C7X0 GEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPK 200 A6NNJ1 ERQTGAAADMPQPAVRHQGREPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQA 300 P0C7X0 ERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQASRPQAQDKRPAVTPQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQA 300 A6NNJ1 CLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSTPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLE 400 P0C7X0 CLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHSAAGHDGAQPLRVLFRRLE 400 A6NNJ1 NGRWSSSLLAAPSFHSPEKPGTFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE 464 P0C7X0 NGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE 464
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source | GO | Description |
---|---|---|
2. P | GO:0016591 | RNA polymerase II, holoenzyme |
2. P | GO:0003682 | chromatin binding |
2. P | GO:0016973 | poly(A)+ mRNA export from nucleus |
2. P | GO:0005665 | RNA polymerase II, core complex |
2. P | GO:0006334 | nucleosome assembly |
2. P | GO:0007051 | spindle organization |
2. P | GO:0005654 | nucleoplasm |
2. P | GO:1903863 | P granule assembly |
2. P | GO:0006333 | chromatin assembly or disassembly |
2. P | GO:0042995 | cell projection |
2. P | GO:0019901 | protein kinase binding |
2. P | GO:0010847 | regulation of chromatin assembly |
2. P | GO:0030849 | autosome |
2. P | GO:0006281 | DNA repair |
2. P | GO:0043486 | histone exchange |
2. P | GO:0003729 | mRNA binding |
2. P | GO:0060088 | auditory receptor cell stereocilium organization |
2. P | GO:0007141 | male meiosis I |
2. P | GO:0001042 | RNA polymerase I core binding |
2. P | GO:0019902 | phosphatase binding |
2. P | GO:1905168 | positive regulation of double-strand break repair via homologous recombination |
2. P | GO:0005813 | centrosome |
2. P | GO:0005652 | nuclear lamina |
2. P | GO:0009792 | embryo development ending in birth or egg hatching |
2. P | GO:0051308 | male meiosis chromosome separation |
2. P | GO:0120044 | stereocilium base |
2. P | GO:0006974 | cellular response to DNA damage stimulus |
2. P | GO:0030870 | Mre11 complex |
2. P | GO:0010212 | response to ionizing radiation |
2. P | GO:0006355 | regulation of transcription, DNA-templated |
2. P | GO:0051685 | maintenance of ER location |
2. P | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining |
2. P | GO:0007095 | mitotic G2 DNA damage checkpoint signaling |
2. P | GO:0071168 | protein localization to chromatin |
2. P | GO:0007344 | pronuclear fusion |
2. P | GO:0006997 | nucleus organization |
2. P | GO:0005635 | nuclear envelope |
2. P | GO:0120045 | stereocilium maintenance |
2. P | GO:0032420 | stereocilium |
2. P | GO:0005730 | nucleolus |
2. P | GO:0045860 | positive regulation of protein kinase activity |
2. P | GO:0042393 | histone binding |
2. P | GO:0006878 | cellular copper ion homeostasis |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
---|---|---|---|---|---|
1. PB | A8MXJ8 | Putative protein FAM90A5P | 1.75e-06 | 1.32e-92 | 0.0 |
1. PB | P0C7W9 | Putative protein FAM90A14P | 9.71e-06 | 6.53e-87 | 0.0 |
1. PB | P0C7V4 | Putative protein FAM90A15P | 1.31e-06 | 3.75e-83 | 0.0 |
1. PB | P0C7W8 | Putative protein FAM90A13P | 1.03e-06 | 2.22e-87 | 0.0 |
1. PB | A6NIJ5 | Putative protein FAM90A20P | 7.03e-05 | 3.75e-87 | 0.0 |
1. PB | A6NNJ1 | Putative protein FAM90A9P | 0 | 3.31e-144 | 0.0 |
1. PB | A6NE21 | Putative protein FAM90A18P/FAM90A19P | 4.65e-07 | 1.32e-120 | 0.0 |
1. PB | Q86YD7 | Protein FAM90A1 | 2.26e-05 | 1.58e-63 | 0.0 |
1. PB | A6NEW6 | Putative protein FAM90A16P/FAM90A17P | 1.82e-06 | 1.63e-96 | 0.0 |
1. PB | A6NJQ4 | Putative protein FAM90A8P | 2.03e-08 | 2.80e-101 | 0.0 |
1. PB | D6RGX4 | Putative protein FAM90A26 | 2.22e-06 | 1.47e-79 | 0.0 |
1. PB | A8MWA6 | Putative protein FAM90A22P | 4.36e-06 | 1.91e-82 | 0.0 |
1. PB | A8MXZ1 | Putative protein FAM90A23P | 3.77e-07 | 6.80e-88 | 0.0 |
1. PB | P0C7X0 | Putative protein FAM90A24P | 1.65e-09 | 5.86e-89 | 0.0 |
1. PB | Q658T7 | Putative protein FAM90A2P | 5.21e-05 | 2.07e-45 | 0.0 |
1. PB | A8MX19 | Putative protein FAM90A12P | 3.98e-04 | 1.39e-95 | 0.0 |
1. PB | A6NNH2 | Protein FAM90A27P | 2.69e-02 | 9.13e-26 | 1.14e-42 |
1. PB | A6NDY2 | Putative protein FAM90A10P | 2.81e-08 | 6.45e-111 | 0.0 |
1. PB | A6NKC0 | Putative protein FAM90A7P | 4.75e-07 | 2.63e-110 | 0.0 |
2. P | B4HMH2 | Protein teflon | 3.43e-01 | 4.39e-02 | NA |
2. P | Q6NZF1 | Zinc finger CCCH domain-containing protein 11A | 6.15e-01 | 1.77e-02 | NA |
2. P | Q8IMP6 | Protein SPT2 homolog | 1.21e-01 | 7.73e-05 | NA |
2. P | Q9D1F5 | MRN complex-interacting protein | 1.66e-01 | 1.66e-02 | NA |
2. P | Q5ZJJ1 | Zinc finger CCCH domain-containing protein 11A | 6.36e-01 | 4.95e-04 | NA |
2. P | P20129 | 70 kDa protein | NA | 2.94e-02 | NA |
2. P | Q5ZK13 | Centrosomal protein kizuna | 3.11e-01 | 8.81e-07 | NA |
2. P | Q2M2Z5 | Centrosomal protein kizuna | 2.29e-01 | 3.52e-05 | NA |
2. P | P25028 | Mitosis initiation protein fs(1)Ya | 3.10e-01 | 4.30e-03 | NA |
2. P | D3YT16 | Enlarged germline granules protein 1 | 3.84e-01 | 1.54e-03 | NA |
2. P | O75152 | Zinc finger CCCH domain-containing protein 11A | 2.86e-01 | 1.19e-02 | NA |
2. P | P0CAP2 | DNA-directed RNA polymerase II subunit GRINL1A | 3.83e-01 | 3.39e-02 | NA |
2. P | Q68D10 | Protein SPT2 homolog | 7.88e-02 | 1.72e-02 | NA |
2. P | A0A1B0GTU1 | Zinc finger CCCH domain-containing protein 11B | 7.78e-01 | 5.45e-03 | NA |
2. P | Q6DGN6 | Protein SPT2 homolog | 3.14e-01 | 7.06e-04 | NA |
2. P | Q3ZBG8 | MRN complex-interacting protein | 2.53e-01 | 1.85e-03 | NA |
2. P | Q8TAL5 | Uncharacterized protein C9orf43 | 4.14e-01 | 4.18e-03 | NA |
2. P | Q4KMQ1 | Taperin | 2.82e-01 | 1.52e-02 | NA |
2. P | Q92258 | Protein GRISEA | 4.54e-01 | 2.22e-02 | NA |
2. P | Q5REG6 | Zinc finger CCCH domain-containing protein 11A | 6.74e-01 | 2.54e-02 | NA |
2. P | Q6NTE8 | MRN complex-interacting protein | 1.70e-01 | 1.45e-04 | NA |
2. P | Q3UXL4 | Centrosomal protein kizuna | 2.92e-01 | 8.17e-04 | NA |
2. P | Q68FG3 | Protein SPT2 homolog | 1.27e-01 | 1.55e-02 | NA |
2. P | Q32PP1 | MRN complex-interacting protein | 7.52e-02 | 8.22e-03 | NA |