Summary

A6NNL0

Homolog: B1AL46.
Function: NUT family member 2E.

Statistics

Total GO Annotation: 18
Unique PROST Go: 17
Unique BLAST Go: 1

Total Homologs: 10
Unique PROST Homologs: 1
Unique BLAST Homologs: 2

Structures and Sequence Alignment

The best structural homolog that predicted by 1. PB was B1AL46 (NUT family member 2E) with a FATCAT P-Value: 3.64e-07 and RMSD of 12.01 angstrom. The sequence alignment identity is 98.9%.
Structural alignment shown in left. Query protein A6NNL0 colored as red in alignment, homolog B1AL46 colored as blue. Query protein A6NNL0 is also shown in right top, homolog B1AL46 showed in right bottom. They are colored based on secondary structures. 

  A6NNL0 MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCPLPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLG 100
  B1AL46 MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAEALHRTSPTPNSCPLPLPLCRMSGVLCSRNLFTFKFSLFQLDSGASGEPGHSLG 100

  A6NNL0 LTLGFSYCGNCQTAVVSAQPEGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCGPSGAGA 200
  B1AL46 LTLGFSYCGNCQTAVVSAQPEGMASNGAYPVLGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTFPSTPLVTEQDGCSPSGAGA 200

  A6NNL0 SNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300
  B1AL46 SNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQGNAGP 300

  A6NNL0 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYE 400
  B1AL46 WPQGAHGESSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYE 400

  A6NNL0 MAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLPPPRP 500
  B1AL46 MAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAQTACLPPPRPQRPVTKARRPPPQPHRRAETKARLPPPRP 500

  A6NNL0 QRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600
  B1AL46 QRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGKVKQPQEEDWTPPDPGLLSYIDKLCSQKDFVTKVEAVIHPQFLEELLSPDPQMDF 600

  A6NNL0 LALSQDLEQEEGLTLAQLVEKRLPPLKEKQHARAAPSRGTARLDSSSSKFAAGQGAERDVPDPQQGVGMETCPPQMTARDSQGRGRAHTGMARSEDSVVL 700
  B1AL46 LALSQDLEQEEGLTLAQLVEKRLPPLKEKQHSRAAPSRGTARLDSSSSKFAAGQGAERDVPDPQEGVGMETCPPQTTARDSQGRGRAHTGMARSEDSVVL 700

  A6NNL0 LGCQDSPGLRAAWPTSPPQDHRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPVPASGLLSPEKWGPQGTHQS 800
  B1AL46 LGCQDSPGLRAARPTSPPQDHRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPVPASGLLSPEKWGPQGTHQS 800

  A6NNL0 PSAERRGLNLAPSPANKAKKRPLFGSLSPAEKTPYPGPGLRVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ 878
  B1AL46 PSAERRGLNLAPSPANKAKKQPLFGSLSPAEKTPHRGPGLRVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQHCSQ 878

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
2. P GO:0048749 compound eye development
2. P GO:0048730 epidermis morphogenesis
2. P GO:0035214 eye-antennal disc development
2. P GO:0007384 specification of segmental identity, thorax
2. P GO:0007450 dorsal/ventral pattern formation, imaginal disc
2. P GO:2000497 positive regulation of cell proliferation involved in compound eye morphogenesis
2. P GO:0016055 Wnt signaling pathway
2. P GO:0061330 Malpighian tubule stellate cell differentiation
2. P GO:0007473 wing disc proximal/distal pattern formation
2. P GO:0045705 negative regulation of salivary gland boundary specification
2. P GO:0007476 imaginal disc-derived wing morphogenesis
2. P GO:0007380 specification of segmental identity, head
2. P GO:0007494 midgut development
2. P GO:0007479 leg disc proximal/distal pattern formation
2. P GO:0008258 head involution
2. P GO:0035292 specification of segmental identity, trunk
3. B GO:0005634 nucleus

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q5VZR2 NUT family member 2G 3.67e-04 1.23e-25 0.0
1. PB Q3V0C3 NUT family member 2 1.21e-03 7.63e-19 1.95e-139
1. PB Q5VT03 NUT family member 2D 5.22e-05 9.04e-46 0.0
1. PB A1L443 NUT family member 2F 8.67e-04 5.26e-28 0.0
1. PB Q8IVF1 NUT family member 2A 4.10e-04 3.15e-122 0.0
1. PB A6NNL0 NUT family member 2B 0 2.83e-152 0.0
1. PB B1AL46 NUT family member 2E 3.64e-07 5.32e-133 0.0
2. P P22265 Protein teashirt 2.83e-01 1.04e-02 NA
3. B Q86Y26 NUT family member 1 7.33e-03 NA 7.35e-122
3. B Q8BHP2 NUT family member 1 8.26e-03 NA 3.97e-106