Summary

A6PVY3

Homolog: O13813.
Function: Mitochondrial import receptor subunit tom22.

Statistics

Total GO Annotation: 6
Unique PROST Go: 6
Unique BLAST Go: 0

Total Homologs: 10
Unique PROST Homologs: 6
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was O13813 (Mitochondrial import receptor subunit tom22) with a FATCAT P-Value: 0.000251 and RMSD of 2.44 angstrom. The sequence alignment identity is 23.8%.
Structural alignment shown in left. Query protein A6PVY3 colored as red in alignment, homolog O13813 colored as blue. Query protein A6PVY3 is also shown in right top, homolog O13813 showed in right bottom. They are colored based on secondary structures. 

  A6PVY3 M-EIDGFQQLDLEKSVPSKKTT--PK-RIIHFVDGDIMEEYSTEEEEEEEKEEQSTNSTLD---------PSKLSWGPYLRFWAG-RIASTSFS-TCEFL 85
  O13813 MVKLE--EVVD-ETEVQNEQQTVIEKDQYIYAQE-DV-EESDSDESDFEGLEEE-T--IIDRIAALKEIVP--VTW--RVKIADGAKTATTGLSKLAQF- 87

  A6PVY3 GGR-------FAVFFGLTQPKYQYV-----LNEFYRIQNKKSDNKSERRGSKAQAAEVPNEKCHLEAGVQEYGTIQQDVTEAIPQ 158
  O13813 GGKSMWVISTSALLLGV--PFMMSLEEEAQLTE-YEKQIK--DQ----RG----ANEV------IAPGAT-SG--------ALPQ 144

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0005741 mitochondrial outer membrane
2. P GO:0005742 mitochondrial outer membrane translocase complex
2. P GO:0030150 protein import into mitochondrial matrix
2. P GO:0070096 mitochondrial outer membrane translocase complex assembly
2. P GO:0031307 integral component of mitochondrial outer membrane
2. P GO:0045040 protein insertion into mitochondrial outer membrane

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB A6PVY3 Protein FAM177B 0 1.50e-145 1.53e-116
1. PB Q8N128 Protein FAM177A1 5.65e-04 3.06e-13 2.12e-32
1. PB Q8BR63 Protein FAM177A1 4.40e-04 1.00e-13 2.17e-31
1. PB A6QLZ5 Protein FAM177A1 2.71e-04 3.31e-13 6.50e-31
2. P Q07335 Mitochondrial import receptor subunit tom22 3.64e-03 1.67e-03 NA
2. P Q6P1V1 Transmembrane protein 263 6.95e-01 2.34e-02 NA
2. P Q8X0G8 Mitochondrial import protein 1 4.64e-02 3.14e-03 NA
2. P P49334 Mitochondrial import receptor subunit TOM22 1.35e-03 1.01e-04 NA
2. P Q3TZW7 Protein BEX6 9.98e-02 2.32e-02 NA
2. P O13813 Mitochondrial import receptor subunit tom22 2.51e-04 1.34e-04 NA