Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PB was
A6NNJ1
(Putative protein FAM90A9P) with a FATCAT P-Value: 2.22e-06 and RMSD of 9.35 angstrom. The sequence alignment identity is 94.2%.
Structural alignment shown in left. Query protein D6RGX4 colored as red in alignment, homolog A6NNJ1 colored as blue.
Query protein D6RGX4 is also shown in right top, homolog A6NNJ1 showed in right bottom. They are colored based on secondary structures.
D6RGX4 MMACRDPKPGAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHMARSTRCPMKCWKAALVPPTLGKKEGKENLKPWKPQVEANPGPLNKDK 100 A6NNJ1 MMARRDPKSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDK 100 D6RGX4 GEKEERPRQQDPQRKALLHIFSGKPPEKPLPNRKGSTESSVYLRVASGPMPVHTTSKRPRVDPVLADRSATEMSDRGSALASLSPLRKASLSSSSSLGPK 200 A6NNJ1 GEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTESSDHLRVASGPMPVHTTSKRPRVDPVLADRSAAEMSGRGSVLASLSPLRKASLSSSSSLGPK 200 D6RGX4 ERQTGAAADIPQPAVRHQGPEPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAISPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQA 300 A6NNJ1 ERQTGAAADMPQPAVRHQGREPLLVVKPTHSSPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQA 300 D6RGX4 CLNFPKKPRLGPFQIPESAIQGGELGAPEYLQPPPATTELGPSTSPQMGRRTPAQVSSVDRQPPHSRPCLPTAQACTMSHHPATSHDGAQPLRVLFRRLE 400 A6NNJ1 CLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSTPCLPTAQACTMSHHSAASHDGAQPLRVLFRRLE 400 D6RGX4 NGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEVPRVRVPPNVLYEDLQVSSSSEDSDSDLE 464 A6NNJ1 NGRWSSSLLAAPSFHSPEKPGTFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE 464
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source | GO | Description |
---|---|---|
2. P | GO:1905168 | positive regulation of double-strand break repair via homologous recombination |
2. P | GO:0045860 | positive regulation of protein kinase activity |
2. P | GO:0003682 | chromatin binding |
2. P | GO:0016973 | poly(A)+ mRNA export from nucleus |
2. P | GO:0005813 | centrosome |
2. P | GO:0009792 | embryo development ending in birth or egg hatching |
2. P | GO:0006334 | nucleosome assembly |
2. P | GO:0007051 | spindle organization |
2. P | GO:0006606 | protein import into nucleus |
2. P | GO:0006974 | cellular response to DNA damage stimulus |
2. P | GO:1903863 | P granule assembly |
2. P | GO:0030870 | Mre11 complex |
2. P | GO:0010212 | response to ionizing radiation |
2. P | GO:0042995 | cell projection |
2. P | GO:0019901 | protein kinase binding |
2. P | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining |
2. P | GO:0010847 | regulation of chromatin assembly |
2. P | GO:0006281 | DNA repair |
2. P | GO:0007095 | mitotic G2 DNA damage checkpoint signaling |
2. P | GO:0071168 | protein localization to chromatin |
2. P | GO:0007417 | central nervous system development |
2. P | GO:0043486 | histone exchange |
2. P | GO:0003729 | mRNA binding |
2. P | GO:0004879 | nuclear receptor activity |
2. P | GO:0005654 | nucleoplasm |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
---|---|---|---|---|---|
1. PB | A8MXJ8 | Putative protein FAM90A5P | 3.42e-04 | 1.25e-92 | 0.0 |
1. PB | P0C7W9 | Putative protein FAM90A14P | 2.79e-04 | 2.12e-89 | 0.0 |
1. PB | P0C7V4 | Putative protein FAM90A15P | 3.13e-04 | 7.32e-90 | 0.0 |
1. PB | P0C7W8 | Putative protein FAM90A13P | 5.29e-05 | 2.14e-91 | 0.0 |
1. PB | A6NIJ5 | Putative protein FAM90A20P | 4.05e-05 | 4.90e-82 | 0.0 |
1. PB | A6NNJ1 | Putative protein FAM90A9P | 2.22e-06 | 1.90e-80 | 0.0 |
1. PB | A6NE21 | Putative protein FAM90A18P/FAM90A19P | 3.76e-05 | 3.15e-80 | 0.0 |
1. PB | Q86YD7 | Protein FAM90A1 | 8.14e-06 | 1.78e-84 | 0.0 |
1. PB | A6NEW6 | Putative protein FAM90A16P/FAM90A17P | 1.63e-05 | 8.36e-84 | 0.0 |
1. PB | A6NJQ4 | Putative protein FAM90A8P | 1.63e-05 | 2.02e-82 | 0.0 |
1. PB | D6RGX4 | Putative protein FAM90A26 | 0 | 5.90e-146 | 0.0 |
1. PB | A8MWA6 | Putative protein FAM90A22P | 2.06e-05 | 1.04e-85 | 0.0 |
1. PB | A8MXZ1 | Putative protein FAM90A23P | 6.69e-06 | 3.99e-88 | 0.0 |
1. PB | P0C7X0 | Putative protein FAM90A24P | 1.24e-04 | 9.61e-91 | 0.0 |
1. PB | Q658T7 | Putative protein FAM90A2P | 5.34e-05 | 1.83e-61 | 0.0 |
1. PB | A8MX19 | Putative protein FAM90A12P | 3.11e-03 | 4.47e-94 | 0.0 |
1. PB | A6NNH2 | Protein FAM90A27P | 1.46e-02 | 2.02e-33 | 1.73e-39 |
1. PB | A6NDY2 | Putative protein FAM90A10P | 2.49e-05 | 3.17e-81 | 0.0 |
1. PB | A6NKC0 | Putative protein FAM90A7P | 6.52e-04 | 1.06e-82 | 0.0 |
2. P | Q3ZBG8 | MRN complex-interacting protein | 3.22e-01 | 1.25e-02 | NA |
2. P | P15370 | Protein embryonic gonad | 3.68e-01 | 3.95e-02 | NA |
2. P | Q8BXQ8 | Protein FAM53C | 3.86e-01 | 1.07e-02 | NA |
2. P | Q5ZK13 | Centrosomal protein kizuna | 1.80e-01 | 1.40e-04 | NA |
2. P | Q2M2Z5 | Centrosomal protein kizuna | 4.25e-01 | 1.05e-02 | NA |
2. P | Q6NZF1 | Zinc finger CCCH domain-containing protein 11A | 2.75e-01 | 5.40e-03 | NA |
2. P | D3YT16 | Enlarged germline granules protein 1 | 5.30e-01 | 2.54e-02 | NA |
2. P | O75152 | Zinc finger CCCH domain-containing protein 11A | 3.87e-01 | 2.96e-03 | NA |
2. P | Q8IMP6 | Protein SPT2 homolog | 1.19e-01 | 5.14e-03 | NA |
2. P | Q5REG6 | Zinc finger CCCH domain-containing protein 11A | 2.24e-01 | 2.85e-03 | NA |
2. P | Q9D1F5 | MRN complex-interacting protein | 1.83e-01 | 1.53e-02 | NA |
2. P | A0A1B0GTU1 | Zinc finger CCCH domain-containing protein 11B | 3.51e-01 | 1.75e-03 | NA |
2. P | Q5ZJJ1 | Zinc finger CCCH domain-containing protein 11A | 1.68e-01 | 1.34e-03 | NA |
2. P | Q6NTE8 | MRN complex-interacting protein | 2.79e-01 | 3.53e-04 | NA |