Summary

H3BPM6

Homolog: Q9CQT7.
Function: Desumoylating isopeptidase 1.

Statistics

Total GO Annotation: 39
Unique PROST Go: 39
Unique BLAST Go: 0

Total Homologs: 36
Unique PROST Homologs: 35
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was Q9CQT7 (Desumoylating isopeptidase 1) with a FATCAT P-Value: 0.000622 and RMSD of 2.12 angstrom. The sequence alignment identity is 23.6%.
Structural alignment shown in left. Query protein H3BPM6 colored as red in alignment, homolog Q9CQT7 colored as blue. Query protein H3BPM6 is also shown in right top, homolog Q9CQT7 showed in right bottom. They are colored based on secondary structures. 

  H3BPM6 MHCAEAGKALIKFNHCEKYIYSFSVPQCCP--LCQQDL--G-SRKLEDAPVSIANPFTNG--HQEKCSFLLRPTQGTFLREYDGRSDLHVGITN-TNGVV 92
  Q9CQT7 ----------------------MEPPNLYPVKLYVYDLSKGLARRL--SPIMLGKQL-EGIWH---TSIVVHKDE--F---FFGSS----GISSCTPG-- 61

  H3BPM6 YNYSAHGVQRDGEGWEESISIPLLQPNMYGMMEQWDK-YLEDFSTSGAWLPHR---YEDN--HHNCYSYALTFINCVLMAEGRQQLDKGEFTEKYVVPRT 186
  Q9CQT7 ------GTLL---GPPDSV-VDV------GNTEVTEEIFLEYLSSLGESL-FRGEAY--NLFEHNCN----TFSNEV--A---QFL-TGRKIPSYI---T 129

  H3BPM6 RLASKFI-TLY-RAIREHGFYVTDCPQQQAQPPEGG---GLC---- 223
  Q9CQT7 DLPSEVLSTPFGQALRP---FL-D--SIQIQPP-GGNSVGRPNGQS 168

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0006776 vitamin A metabolic process
2. P GO:0048471 perinuclear region of cytoplasm
2. P GO:1990830 cellular response to leukemia inhibitory factor
2. P GO:0006611 protein export from nucleus
2. P GO:0009617 response to bacterium
2. P GO:0005771 multivesicular body
2. P GO:0050896 response to stimulus
2. P GO:0007601 visual perception
2. P GO:0016926 protein desumoylation
2. P GO:0010104 regulation of ethylene-activated signaling pathway
2. P GO:0070140 SUMO-specific isopeptidase activity
2. P GO:0047173 phosphatidylcholine-retinol O-acyltransferase activity
2. P GO:0009723 response to ethylene
2. P GO:0102279 lecithin:11-cis retinol acyltransferase activity
2. P GO:0019841 retinol binding
2. P GO:0005791 rough endoplasmic reticulum
2. P GO:0032370 positive regulation of lipid transport
2. P GO:0033189 response to vitamin A
2. P GO:0001523 retinoid metabolic process
2. P GO:0043231 intracellular membrane-bounded organelle
2. P GO:0070646 protein modification by small protein removal
2. P GO:0004197 cysteine-type endopeptidase activity
2. P GO:0042025 host cell nucleus
2. P GO:0000902 cell morphogenesis
2. P GO:0005783 endoplasmic reticulum
2. P GO:0032991 protein-containing complex
2. P GO:0008374 O-acyltransferase activity
2. P GO:0048870 cell motility
2. P GO:0042572 retinol metabolic process
2. P GO:0061676 importin-alpha family protein binding
2. P GO:0001972 retinoic acid binding
2. P GO:0016416 O-palmitoyltransferase activity
2. P GO:0005789 endoplasmic reticulum membrane
2. P GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process
2. P GO:0005615 extracellular space
2. P GO:0010105 negative regulation of ethylene-activated signaling pathway
2. P GO:0042802 identical protein binding
2. P GO:0006653 1,2-diacyl-sn-glycero-3-phosphocholine metabolic process
2. P GO:0032526 response to retinoic acid

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB H3BPM6 MKRN2 opposite strand protein 0 3.49e-139 9.16e-172
2. P Q9CQT7 Desumoylating isopeptidase 1 6.22e-04 1.38e-07 NA
2. P P21027 Uncharacterized protein G6 NA 6.41e-04 NA
2. P P0DOU3 Uncharacterized protein G6 NA 1.59e-03 NA
2. P O95237 Lecithin retinol acyltransferase 3.40e-02 8.88e-06 NA
2. P Q96KN1 Protein LRATD2 8.18e-02 2.75e-05 NA
2. P P68986 Protease NA 3.18e-03 NA
2. P P68985 Protease NA 3.18e-03 NA
2. P P10381 Protease NA 4.18e-03 NA
2. P Q9JI61 Lecithin retinol acyltransferase 2.46e-02 5.08e-04 NA
2. P P19151 Protease NA 3.19e-02 NA
2. P B4YNE9 Uncharacterized protein V9 NA 1.37e-06 NA
2. P P68984 Protease NA 3.18e-03 NA
2. P Q9JI60 Lecithin retinol acyltransferase 2.93e-02 5.20e-03 NA
2. P Q63K42 Effector protein BopA 3.23e-01 2.21e-02 NA
2. P Q8BVA2 Transmembrane protein 222 2.91e-03 6.35e-08 NA
2. P Q62B16 Effector protein BopA 3.98e-01 4.48e-02 NA
2. P Q6GLM5 Desumoylating isopeptidase 1 7.44e-04 2.37e-09 NA
2. P Q5UQV2 Uncharacterized protein R372 NA 4.38e-04 NA
2. P A2S1Q9 Effector protein BopA 3.29e-01 4.48e-02 NA
2. P Q80HW9 Uncharacterized protein G6 NA 5.95e-04 NA
2. P Q196X8 Uncharacterized protein 082L NA 1.46e-02 NA
2. P Q3ZCA1 Protein LRATD1 5.78e-02 5.17e-06 NA
2. P Q9BGL2 Lecithin retinol acyltransferase 2.92e-02 4.42e-05 NA
2. P Q4KM30 Desumoylating isopeptidase 1 6.28e-04 1.38e-07 NA
2. P F4ITL6 Protein REVERSION-TO-ETHYLENE SENSITIVITY1 7.12e-04 7.71e-10 NA
2. P P33546 Virulence protein IcsB 2.64e-01 1.74e-03 NA
2. P Q3JL32 Effector protein BopA 4.36e-01 2.21e-02 NA
2. P Q9H0R3 Transmembrane protein 222 3.52e-03 3.37e-07 NA
2. P P32167 Uncharacterized protein YiiX 5.66e-03 6.76e-04 NA
2. P A3MCH8 Effector protein BopA 3.36e-01 4.48e-02 NA
2. P P0DOU4 Uncharacterized protein G6 NA 1.59e-03 NA
2. P Q9D650 Protein LRATD1 5.00e-02 7.08e-05 NA
2. P Q2T703 Effector protein BopA 2.29e-01 7.67e-04 NA
2. P Q6ICB0 Desumoylating isopeptidase 1 2.89e-03 4.27e-07 NA
2. P Q96KN4 Protein LRATD1 4.47e-02 1.47e-04 NA