Summary

O60756

Homolog: Q9HBF5.
Function: Suppressor of tumorigenicity 20 protein.

Statistics

Total GO Annotation: 8
Unique PROST Go: 8
Unique BLAST Go: 0

Total Homologs: 8
Unique PROST Homologs: 7
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was Q9HBF5 (Suppressor of tumorigenicity 20 protein) with a FATCAT P-Value: 0.0268 and RMSD of 2.41 angstrom. The sequence alignment identity is 22.4%.
Structural alignment shown in left. Query protein O60756 colored as red in alignment, homolog Q9HBF5 colored as blue. Query protein O60756 is also shown in right top, homolog Q9HBF5 showed in right bottom. They are colored based on secondary structures. 

  O60756 MGRTP-TAVQVKSFTKQGQQRRVCRDLPLKNTKNG----LS-PGMRTC-FLYLRFFPC----LSWMSLKWTQAVHCARNIVLSFMLLL-LLLN-YNM- 84
  Q9HBF5 MARSRLTATSVSQVQENGFVKKL--E-P----KSGWMTFLEVTG-KICEMLF-----CPEAIL--LTRKDTP--YCETGLI--FLTLTKTIANTYFYF 79

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
2. P GO:0030331 estrogen receptor binding
2. P GO:1902512 positive regulation of apoptotic DNA fragmentation
2. P GO:0071494 cellular response to UV-C
2. P GO:0097190 apoptotic signaling pathway
2. P GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
2. P GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway
2. P GO:0030308 negative regulation of cell growth

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB O60756 Putative protein BCE-1 0 6.92e-131 1.18e-57
2. P G2TRK6 Putative uncharacterized protein C9G1.14 1.97e-04 4.21e-02 NA
2. P Q8NEQ6 Steroid receptor-associated and regulated protein 1.88e-01 1.53e-03 NA
2. P P53105 Putative uncharacterized protein YGL177W 4.37e-02 1.01e-02 NA
2. P P20562 Uncharacterized 9.9 kDa protein NA 1.71e-02 NA
2. P P20566 Uncharacterized 8.4 kDa protein NA 6.17e-03 NA
2. P P0C5M7 Putative uncharacterized protein YEL050W-A 2.37e-04 8.04e-03 NA
2. P Q9HBF5 Suppressor of tumorigenicity 20 protein 2.68e-02 1.02e-04 NA