Summary

O95567

Homolog: Q9HB09.
Function: Bcl-2-like protein 12.

Statistics

Total GO Annotation: 12
Unique PROST Go: 12
Unique BLAST Go: 0

Total Homologs: 5
Unique PROST Homologs: 4
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was Q9HB09 (Bcl-2-like protein 12) with a FATCAT P-Value: 0.0143 and RMSD of 3.41 angstrom. The sequence alignment identity is 20.4%.
Structural alignment shown in left. Query protein O95567 colored as red in alignment, homolog Q9HB09 colored as blue. Query protein O95567 is also shown in right top, homolog Q9HB09 showed in right bottom. They are colored based on secondary structures. 

  O95567 M-HPINVRRDPSI-PIYGLRQSILLNTRLQDCYVDSPALTNIWMARTCAKQNI-NAPA--PATTSSWEVVR-NPL-IASSFSLVKLV-L--RR-QL---K 86
  Q9HB09 MGRPAGLF--PPLCPFLGFRP--------EAC----------W-ER---HMQIERAPSVPPFL--RWAGYRPGPVRRRGKVELIKFVRVQWRRPQVEWRR 74

  O95567 NKCCPPPCKFG---EGKLSKRLKHKDDSVMKATQQARKR-----NFISSKSKQPAGH---------RR--PA--G-GIRESKESSKEKKLTVR--QDLE- 161
  Q9HB09 RRWGPGP---GASMAG--SEELGLREDTL-RVLAAFLRRGEAAGSPVPTPPRSPAQEEPTDFLSRLRRCLPCSLGRGAAPS-ESPRPCSLPIRPCYGLEP 167

  O95567 -----DRYAEHVAATQALPQDSGTAAWKGRVLLPETQKRQQLSEDTLTIHGLP-TEGYQALYH---AVV--EPMLWNP--SGTPK-RYSL-ELGKAIKQK 246
  Q9HB09 GPATPDFYA--LVA-QRLEQ-----------LVQEQLKSPP-SPE---LQGPPSTE-KEAILRRLVALLEEEAEVINQKLASDPALRSKLVRLSSDSFAR 248

  O95567 LWEALCSQGAISEGAQRDRF-PGRKQPGVHEEPV--LKKWPKLKSKK--------------------------------------------- 290
  Q9HB09 LVELFCSR---DDSSRPSRACPGPPPPS--PEPLARLALAMEL-SRRVAGLGGTLAGLSVEHVHSFTPWIQAHGGWEGILAVSPVDLNLPLD 334

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0035486 cytosine/cytosine mispair binding
2. P GO:0006915 apoptotic process
2. P GO:0035488 cytosine/thymine mispair binding
2. P GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process
2. P GO:2001236 regulation of extrinsic apoptotic signaling pathway
2. P GO:0032141 single cytosine insertion binding
2. P GO:0005739 mitochondrion
2. P GO:0032136 adenine/cytosine mispair binding
2. P GO:0003684 damaged DNA binding
2. P GO:0030983 mismatched DNA binding
2. P GO:0035487 thymine/thymine mispair binding
2. P GO:0008301 DNA binding, bending

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB O95567 Uncharacterized protein C22orf31 0 4.79e-145 0.0
2. P B6HDT2 Required for respiratory growth protein 9, mitochondrial 5.20e-02 4.60e-03 NA
2. P Q9HB09 Bcl-2-like protein 12 1.43e-02 4.38e-03 NA
2. P Q10241 Mismatch-binding protein cmb1 9.90e-02 2.06e-04 NA
2. P Q8IWP9 Coiled-coil domain-containing protein 28A 3.20e-02 9.09e-03 NA