Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PB was
P0C7V4
(Putative protein FAM90A15P) with a FATCAT P-Value: 7.93e-12 and RMSD of 4.53 angstrom. The sequence alignment identity is 99.8%.
Structural alignment shown in left. Query protein P0C7W8 colored as red in alignment, homolog P0C7V4 colored as blue.
Query protein P0C7W8 is also shown in right top, homolog P0C7V4 showed in right bottom. They are colored based on secondary structures.
P0C7W8 MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRGEANPGPLNKDK 100 P0C7V4 MMARRDPTSWAKRLVRAQTLQKQRRAPVGPRAPPPDEEDPRLKCKNCGAFGHTARSTRCPMKCWKAALVPATLGKKEGKENLKPWKPRVEANPGPLNKDK 100 P0C7W8 GEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTEPSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPK 200 P0C7V4 GEKEERPRQQDPQRKALLHMFSGKPPEKPLPNGKGSTEPSDYLRVASGPMPVHTTSKRPRLDPVLADRSATEMSGRGSVLASLSPLRKASLSSSSSLGPK 200 P0C7W8 ERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQA 300 P0C7V4 ERQTGAAADMPQPAVRHQGREPLLVVKPTHSRPEGGCREVPQAASKTHGLLQAARPQAQDKRPAVTSQPCPPAATHSLGLGSNLSFGPGAKRPAQAPIQA 300 P0C7W8 CLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLE 400 P0C7V4 CLNFPKKPRLGPFQIPESAIQGGELGAPENLQPPPAATELGPSTSPQMGRRTPAQVPSVDRQPPHSRPCLPTAQACTMSHHPAASHDGAQPLRVLFRRLE 400 P0C7W8 NGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE 464 P0C7V4 NGRWSSSLLAAPSFHSPEKPGAFLAQSPHVSEKSEAPCVRVPPSVLYEDLQVSSSSEDSDSDLE 464
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source | GO | Description |
---|---|---|
2. P | GO:1905168 | positive regulation of double-strand break repair via homologous recombination |
2. P | GO:0003682 | chromatin binding |
2. P | GO:0016973 | poly(A)+ mRNA export from nucleus |
2. P | GO:0005813 | centrosome |
2. P | GO:0006334 | nucleosome assembly |
2. P | GO:0007051 | spindle organization |
2. P | GO:0006974 | cellular response to DNA damage stimulus |
2. P | GO:0010212 | response to ionizing radiation |
2. P | GO:0042995 | cell projection |
2. P | GO:0019901 | protein kinase binding |
2. P | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining |
2. P | GO:0010847 | regulation of chromatin assembly |
2. P | GO:0007095 | mitotic G2 DNA damage checkpoint signaling |
2. P | GO:0071168 | protein localization to chromatin |
2. P | GO:0042393 | histone binding |
2. P | GO:0043486 | histone exchange |
2. P | GO:0003729 | mRNA binding |
2. P | GO:0045860 | positive regulation of protein kinase activity |
2. P | GO:0005654 | nucleoplasm |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
---|---|---|---|---|---|
1. PB | A8MXJ8 | Putative protein FAM90A5P | 8.32e-06 | 1.00e-109 | 0.0 |
1. PB | P0C7W9 | Putative protein FAM90A14P | 4.14e-05 | 9.75e-127 | 0.0 |
1. PB | P0C7V4 | Putative protein FAM90A15P | 7.93e-12 | 5.34e-129 | 0.0 |
1. PB | P0C7W8 | Putative protein FAM90A13P | 0 | 1.53e-143 | 0.0 |
1. PB | A6NIJ5 | Putative protein FAM90A20P | 2.63e-06 | 7.03e-80 | 0.0 |
1. PB | A6NNJ1 | Putative protein FAM90A9P | 1.03e-06 | 7.80e-86 | 0.0 |
1. PB | A6NE21 | Putative protein FAM90A18P/FAM90A19P | 9.33e-09 | 2.00e-82 | 0.0 |
1. PB | Q86YD7 | Protein FAM90A1 | 7.10e-08 | 6.54e-78 | 0.0 |
1. PB | A6NEW6 | Putative protein FAM90A16P/FAM90A17P | 1.40e-05 | 8.82e-109 | 0.0 |
1. PB | A6NJQ4 | Putative protein FAM90A8P | 5.36e-08 | 1.18e-104 | 0.0 |
1. PB | D6RGX4 | Putative protein FAM90A26 | 5.29e-05 | 7.40e-89 | 0.0 |
1. PB | A8MWA6 | Putative protein FAM90A22P | 1.19e-08 | 3.48e-97 | 0.0 |
1. PB | A8MXZ1 | Putative protein FAM90A23P | 5.33e-08 | 1.95e-122 | 0.0 |
1. PB | P0C7X0 | Putative protein FAM90A24P | 2.21e-06 | 3.02e-125 | 0.0 |
1. PB | Q658T7 | Putative protein FAM90A2P | 9.23e-07 | 4.26e-56 | 0.0 |
1. PB | A8MX19 | Putative protein FAM90A12P | 4.20e-04 | 2.02e-108 | 0.0 |
1. PB | A6NNH2 | Protein FAM90A27P | 5.38e-03 | 5.51e-35 | 2.01e-42 |
1. PB | A6NDY2 | Putative protein FAM90A10P | 2.85e-07 | 1.12e-81 | 0.0 |
1. PB | A6NKC0 | Putative protein FAM90A7P | 1.95e-07 | 1.62e-92 | 0.0 |
2. P | Q3ZBG8 | MRN complex-interacting protein | 7.87e-02 | 4.26e-02 | NA |
2. P | Q5ZK13 | Centrosomal protein kizuna | 3.27e-01 | 5.71e-05 | NA |
2. P | Q2M2Z5 | Centrosomal protein kizuna | 1.94e-01 | 4.50e-02 | NA |
2. P | Q8TAL5 | Uncharacterized protein C9orf43 | 3.97e-01 | 5.05e-03 | NA |
2. P | Q6NZF1 | Zinc finger CCCH domain-containing protein 11A | 5.16e-01 | 7.91e-03 | NA |
2. P | O75152 | Zinc finger CCCH domain-containing protein 11A | 6.47e-01 | 7.76e-03 | NA |
2. P | Q8IMP6 | Protein SPT2 homolog | 3.29e-01 | 4.93e-04 | NA |
2. P | Q5REG6 | Zinc finger CCCH domain-containing protein 11A | 5.84e-01 | 2.55e-02 | NA |
2. P | A0A1B0GTU1 | Zinc finger CCCH domain-containing protein 11B | 3.97e-01 | 1.00e-03 | NA |
2. P | Q5ZJJ1 | Zinc finger CCCH domain-containing protein 11A | 2.15e-01 | 5.20e-04 | NA |
2. P | Q6NTE8 | MRN complex-interacting protein | 1.91e-01 | 6.24e-04 | NA |