Summary

P0C875

Homolog: Q497Q6.
Function: Protein FAM228B.

Statistics

Total GO Annotation: 6
Unique PROST Go: 6
Unique BLAST Go: 0

Total Homologs: 10
Unique PROST Homologs: 3
Unique BLAST Homologs: 5

Structures and Sequence Alignment

The best structural homolog that predicted by 3. B was Q497Q6 (Protein FAM228B) with a FATCAT P-Value: 2.07e-12 and RMSD of 2.27 angstrom. The sequence alignment identity is 55.4%.
Structural alignment shown in left. Query protein P0C875 colored as red in alignment, homolog Q497Q6 colored as blue. Query protein P0C875 is also shown in right top, homolog Q497Q6 showed in right bottom. They are colored based on secondary structures. 

  P0C875 ---MKNVDSDDLVTGTLPKLKSSKEWLEPKPLCFMEVLAKEDTEAAIQSILYKENSVIKELDKYLQHHAFLNARRKEMLYKRWVDCVADPLQKKIIEKVC 97
  Q497Q6 MTTMKNRSQDDMVTGTLPKLKSSKEWLEPQSLSFMEALAKEDTDAAVQSILYRENYIMKELDKYLHHQDFLNTRRKEMLYKKWVERVADPLQKKIIEKVH 100

  P0C875 SHKKIKKRRQGELDGFLKHVNKKGNAFIEHYDPKEYDPFYMSKKDPNFLKVTIPPFHDPLKKAQYDKDNEKRTLLQCETGKIYSIKEFKEVEKVQLHSRF 197
  Q497Q6 SHKNIKKRRRQELDNFLKHSNKKGNAFIEHYDPKEYDPFYMSKEDPNFLKVIMPPFRDPLKKAQYDQDDEKRTLLQCETGKIYTMKEFKEIEKAQLHSRF 200

  P0C875 PQISNSRHFITPNEWLKLPTRYIESEFCRRRRLKVKVNFNDCSFDLKPLARAPYLLESQEEEKTVIYKNKGSSFLEREPLCYQEGNNPSAKEAISEGYFS 297
  Q497Q6 PSISNSRQSMTPNGWLKVPMSYIESEFCKKSR-------------------------------------------------------------------- 232

  P0C875 SLSLSQEREEDQDGSPSPRLGLLKLEL 324
  Q497Q6 --------------------------- 232

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0043014 alpha-tubulin binding
2. P GO:0008285 negative regulation of cell population proliferation
2. P GO:0030154 cell differentiation
2. P GO:0048487 beta-tubulin binding
2. P GO:0002357 defense response to tumor cell
2. P GO:0007283 spermatogenesis

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB P0C875 Protein FAM228B 0 9.33e-152 0.0
1. PB A6QQ68 Protein FAM228B 1.33e-07 4.53e-05 3.54e-145
2. P Q68FQ8 Deleted in lung and esophageal cancer protein 1 homolog 1.50e-02 2.29e-02 NA
2. P Q8WW14 Uncharacterized protein C10orf82 9.92e-02 4.94e-02 NA
2. P Q5ZIH9 Coiled-coil domain-containing protein 174 4.59e-02 2.48e-02 NA
3. B Q5XIN5 Protein FAM228A 7.02e-03 NA 2.35e-27
3. B Q86W67 Protein FAM228A 9.41e-02 NA 2.54e-17
3. B Q32KQ1 Protein FAM228A 1.47e-04 NA 2.33e-52
3. B Q8CDW1 Protein FAM228A 5.01e-03 NA 5.51e-22
3. B Q497Q6 Protein FAM228B 2.07e-12 NA 1.35e-134