Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PB was
Q8BRE0
(Protein RD3) with a FATCAT P-Value: 2.65e-07 and RMSD of 2.51 angstrom. The sequence alignment identity is 33.2%.
Structural alignment shown in left. Query protein P0DJH9 colored as red in alignment, homolog Q8BRE0 colored as blue.
Query protein P0DJH9 is also shown in right top, homolog Q8BRE0 showed in right bottom. They are colored based on secondary structures.
P0DJH9 MPLFGWMKWPKNDSYKP---THYPGSDIVTKTLLRELKWHLKERERLIQEIENEQKVKK--TGVDYNWLRNYQNPHTTIPVT--EQRQLEVLCSQVQP-- 91 Q8BRE0 MSLIPWLRW--NDT-PPRLSARTP-AEMVLETLMMELAGQMREVER--QQRERRSAVRKICTGVDYSWLAN--TPRPTYDISPGERLQLEDVCAKIHPSY 92 P0DJH9 CQTG-TILSRFREVLAENDVLP--WEIVYIFKQVLKDFLSSSDRGSEQEDLEDSGSMDCSA-PSVIQGD-SS-K-RAD----KDEIPTISSYVDKNTKDR 180 Q8BRE0 C--GPAIL-RFRQLLAERE--PEVQEVARLFRSVLQEAL---EK-MKQEEEAHKLTRQWSLRP---RGSLSSFKTRARIAPFASDIRTISEDVE---RDA 177 P0DJH9 FPVFSHRIWNLPYYH-PSS- 198 Q8BRE0 PP--PPRTWSMPEFRAPQAD 195
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source | GO | Description |
---|---|---|
1. PB | GO:0048471 | perinuclear region of cytoplasm |
1. PB | GO:0005768 | endosome |
1. PB | GO:0120200 | rod photoreceptor outer segment |
1. PB | GO:0120199 | cone photoreceptor outer segment |
1. PB | GO:0007601 | visual perception |
1. PB | GO:0015031 | protein transport |
1. PB | GO:0001917 | photoreceptor inner segment |
1. PB | GO:0031283 | negative regulation of guanylate cyclase activity |
1. PB | GO:0001750 | photoreceptor outer segment |
1. PB | GO:0050896 | response to stimulus |
1. PB | GO:0060041 | retina development in camera-type eye |
2. P | GO:0007049 | cell cycle |
2. P | GO:0000187 | obsolete activation of MAPK activity |
2. P | GO:0009968 | negative regulation of signal transduction |
2. P | GO:0005634 | nucleus |
2. P | GO:0043410 | positive regulation of MAPK cascade |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
---|---|---|---|---|---|
1. PB | Q8BRE0 | Protein RD3 | 2.65e-07 | 4.11e-05 | 1.41e-16 |
1. PB | Q7Z3Z2 | Protein RD3 | 1.53e-06 | 3.23e-03 | 3.33e-16 |
1. PB | P0DJH9 | Protein RD3-like | 0 | 1.50e-142 | 2.94e-148 |
2. P | Q8VDA6 | Arginine vasopressin-induced protein 1 | 1.97e-01 | 1.50e-02 | NA |
2. P | Q4V9P3 | Regulator of G-protein signaling 7-binding protein B | 3.29e-03 | 1.93e-02 | NA |
2. P | Q9D7H4 | Arginine vasopressin-induced protein 1 | 2.52e-01 | 6.96e-04 | NA |
2. P | B0BK70 | Orofacial cleft 1 candidate gene 1 protein homolog | 1.38e-01 | 4.81e-02 | NA |