Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 3. B was
Q8BPW0
(IQ domain-containing protein J) with a FATCAT P-Value: 0.0224 and RMSD of 4.13 angstrom. The sequence alignment identity is 57.5%.
Structural alignment shown in left. Query protein Q1A5X6 colored as red in alignment, homolog Q8BPW0 colored as blue.
Query protein Q1A5X6 is also shown in right top, homolog Q8BPW0 showed in right bottom. They are colored based on secondary structures.
Q1A5X6 MRLEELKRLQNPLEQVNDGKYSFENHQLAMDAENNIEKYPLNLQPLESKVKIIQRAWREYLQRQEPLGKRSPSPPSVSSEKLSSSVSMNTFSDSSTPFAR 100 Q8BPW0 MRLEELKRLQNPLEQVDDGKYLLENHQLAMDVENNIENYPLSLQPLESKVKIIQRAWREYLQRQDPLEKRSPSPPSVSSDKLSSSVSMNTFSDSSTPVS- 99 Q1A5X6 APVGKIHPYISWR-LQSPGDKLPGGRKVILLYLDQLARPTGFIHTLKEPQIERLGFLTLQ 159 Q8BPW0 --VSR--P-LAWTVLH-------------------------------------------- 110
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
| Source | GO | Description |
|---|---|---|
| 3. B | GO:0043194 | axon initial segment |
| 3. B | GO:0033268 | node of Ranvier |
| 3. B | GO:0044325 | transmembrane transporter binding |
| 3. B | GO:0051494 | negative regulation of cytoskeleton organization |
| 3. B | GO:0030054 | cell junction |
| 3. B | GO:0005516 | calmodulin binding |
| 3. B | GO:0035332 | positive regulation of hippo signaling |
| 3. B | GO:0008366 | axon ensheathment |
| 3. B | GO:0030506 | ankyrin binding |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
| Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
|---|---|---|---|---|---|
| 1. PB | Q1A5X6 | IQ domain-containing protein J | 0 | 3.86e-139 | 1.29e-114 |
| 3. B | B3KU38 | IQCJ-SCHIP1 readthrough transcript protein | 6.77e-01 | NA | 1.62e-60 |
| 3. B | A0A088MLT8 | IQCJ-SCHIP1 readthrough transcript protein | 5.12e-01 | NA | 2.97e-40 |
| 3. B | Q8BPW0 | IQ domain-containing protein J | 2.24e-02 | NA | 1.95e-44 |