Summary

Q49AS3

Homolog: B2VJD3.
Function: Flagellar transcriptional regulator FlhD.

Statistics

Total GO Annotation: 36
Unique PROST Go: 35
Unique BLAST Go: 1

Total Homologs: 50
Unique PROST Homologs: 45
Unique BLAST Homologs: 4

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was B2VJD3 (Flagellar transcriptional regulator FlhD) with a FATCAT P-Value: 0.00024 and RMSD of 1.71 angstrom. The sequence alignment identity is 20.7%.
Structural alignment shown in left. Query protein Q49AS3 colored as red in alignment, homolog B2VJD3 colored as blue. Query protein Q49AS3 is also shown in right top, homolog B2VJD3 showed in right bottom. They are colored based on secondary structures. 

  Q49AS3 ---MNRN-ILEEM----LQYLLI-DWIVGDQ-----FEIQLNQ----QLWSL-IP-------NNDV---RRLVSHVIRTLKTDCT-ETHLQ-LACAKLIS 69
  B2VJD3 MEKMGTSELLKHIYDINLSYLLLAQRIINQEKVSAMFRLGIDEAMADALASLTLPEMVKLAETNQLVCQFRFNDH--QSI-TRLTQESRVEDL--QQI-- 93

  Q49AS3 RTGLLM--KLLSE-QQELRTVSMTAWKPRMNRKSRSRMRS 106
  B2VJD3 HTGILLSSRLLRDVSQENKT-------PK--KRAVS---- 120

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0090698 post-embryonic plant morphogenesis
2. P GO:0046718 viral entry into host cell
2. P GO:0009399 nitrogen fixation
2. P GO:0035458 cellular response to interferon-beta
2. P GO:0075732 viral penetration into host nucleus
2. P GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors
2. P GO:0005080 protein kinase C binding
2. P GO:0019051 induction by virus of host apoptotic process
2. P GO:0005758 mitochondrial intermembrane space
2. P GO:0039592 suppression by virus of G2/M transition of host mitotic cell cycle
2. P GO:0044780 bacterial-type flagellum assembly
2. P GO:0019058 viral life cycle
2. P GO:0097169 AIM2 inflammasome complex
2. P GO:0046325 negative regulation of glucose import
2. P GO:0042025 host cell nucleus
2. P GO:0039503 suppression by virus of host innate immune response
2. P GO:0005875 microtubule associated complex
2. P GO:0006915 apoptotic process
2. P GO:0039524 suppression by virus of host mRNA processing
2. P GO:0098586 cellular response to virus
2. P GO:0030153 bacteriocin immunity
2. P GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
2. P GO:0002218 activation of innate immune response
2. P GO:0030683 mitigation of host immune response by virus
2. P GO:0009299 mRNA transcription
2. P GO:1902208 regulation of bacterial-type flagellum assembly
2. P GO:0000165 MAPK cascade
2. P GO:0008643 carbohydrate transport
2. P GO:0043278 response to morphine
2. P GO:0007049 cell cycle
2. P GO:0043655 host extracellular space
2. P GO:0031333 negative regulation of protein-containing complex assembly
2. P GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
2. P GO:0009416 response to light stimulus
2. P GO:0005654 nucleoplasm
3. B GO:0016021 integral component of membrane

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q49AS3 Putative protein LRRC37A5P 0 2.75e-122 3.01e-73
2. P Q48864 Sakacin-A immunity factor 1.20e-02 2.11e-02 NA
2. P W6CW81 Pyrin domain-containing protein 5 2.22e-03 1.07e-02 NA
2. P Q5R529 Astrocytic phosphoprotein PEA-15 1.19e-02 4.35e-04 NA
2. P Q2G2A2 UPF0223 protein SAOUHSC_01044 3.41e-04 1.31e-02 NA
2. P Q2FHY3 UPF0223 protein SAUSA300_0997 3.38e-04 1.31e-02 NA
2. P O83065 Uncharacterized protein TP_0021 1.29e-02 1.86e-02 NA
2. P P67360 UPF0223 protein MW0980 3.49e-04 1.31e-02 NA
2. P Q15121 Astrocytic phosphoprotein PEA-15 9.82e-03 4.35e-04 NA
2. P Q039F0 UPF0346 protein LSEI_1394 2.46e-02 7.00e-04 NA
2. P A8Z1N7 UPF0223 protein USA300HOU_1040 3.42e-04 1.31e-02 NA
2. P A6U0R5 UPF0223 protein SaurJH1_1179 3.34e-04 1.31e-02 NA
2. P P27984 Protein Vpx NA 1.38e-03 NA
2. P Q13N12 Nitrogenase-stabilizing/protective protein NifW 2.36e-02 2.36e-04 NA
2. P Q5NLF0 Nitrogenase-stabilizing/protective protein NifW 7.63e-03 1.48e-02 NA
2. P P05930 Protein Vpr NA 3.93e-02 NA
2. P P26481 Nitrogenase-stabilizing/protective protein NifW 1.22e-02 6.35e-04 NA
2. P B3WE94 UPF0346 protein LCABL_16140 1.78e-02 7.00e-04 NA
2. P P05918 Protein Vpx NA 8.01e-06 NA
2. P Q969E8 Pre-rRNA-processing protein TSR2 homolog 4.99e-03 3.27e-03 NA
2. P Q02842 Protein Vpx NA 7.17e-03 NA
2. P P67359 UPF0223 protein SA0947 3.40e-04 1.31e-02 NA
2. P A5IRY4 UPF0223 protein SaurJH9_1157 3.53e-04 1.31e-02 NA
2. P Q5U318 Astrocytic phosphoprotein PEA-15 1.03e-02 4.35e-04 NA
2. P P67358 UPF0223 protein SAV1097 3.86e-04 1.31e-02 NA
2. P Q9Z297 Astrocytic phosphoprotein PEA-15 8.09e-03 4.35e-04 NA
2. P Q66633 Uncharacterized gene 30 protein NA 2.83e-02 NA
2. P B5RTE0 Cx9C motif-containing protein 4, mitochondrial 1.84e-02 2.76e-02 NA
2. P B3DZB3 Nitrogenase-stabilizing/protective protein NifW 2.09e-02 1.57e-04 NA
2. P Q6CS47 Cytochrome c oxidase assembly protein COX19 1.44e-01 6.73e-03 NA
2. P A6QFV3 UPF0223 protein NWMN_0963 3.34e-04 1.31e-02 NA
2. P A1VPP2 Nitrogenase-stabilizing/protective protein NifW 2.93e-02 4.23e-03 NA
2. P Q79668 Protein Vpr NA 1.35e-03 NA
2. P O05234 Uncharacterized protein YugE 5.91e-04 4.51e-03 NA
2. P P18046 Protein Vpr NA 1.68e-03 NA
2. P Q62048 Astrocytic phosphoprotein PEA-15 1.18e-02 5.39e-04 NA
2. P P11130 Protein P13 NA 2.76e-02 NA
2. P P27976 Protein Vpx NA 1.29e-05 NA
2. P A7X0Z9 UPF0223 protein SAHV_1089 3.49e-04 1.31e-02 NA
2. P P05958 Protein Vpr NA 5.87e-03 NA
2. P Q5HGY7 UPF0223 protein SACOL1106 3.43e-04 1.31e-02 NA
2. P Q9FZ51 Protein LIGHT-DEPENDENT SHORT HYPOCOTYLS 8 7.49e-03 1.93e-02 NA
2. P Q84056 Non-structural protein 1 (Fragment) NA 2.12e-02 NA
2. P Q6GAB7 UPF0223 protein SAS1032 3.87e-04 1.31e-02 NA
2. P Q2YX76 UPF0223 protein SAB0963 3.85e-04 1.24e-02 NA
2. P B2VJD3 Flagellar transcriptional regulator FlhD 2.40e-04 4.28e-02 NA
3. B Q96QE4 Leucine-rich repeat-containing protein 37B 4.70e-02 NA 7.57e-26
3. B A6NMS7 Leucine-rich repeat-containing protein 37A 2.49e-01 NA 4.87e-27
3. B O60309 Leucine-rich repeat-containing protein 37A3 2.43e-01 NA 1.82e-26
3. B A6NM11 Leucine-rich repeat-containing protein 37A2 3.61e-01 NA 4.87e-27