Summary

Q5SNV9

Homolog: Q95KD7.
Function: Coiled-coil domain-containing protein 191.

Statistics

Total GO Annotation: 10
Unique PROST Go: 10
Unique BLAST Go: 0

Total Homologs: 5
Unique PROST Homologs: 3
Unique BLAST Homologs: 1

Structures and Sequence Alignment

The best structural homolog that predicted by 3. B was Q95KD7 (Coiled-coil domain-containing protein 191) with a FATCAT P-Value: 0.00276 and RMSD of 14.96 angstrom. The sequence alignment identity is 17.9%.
Structural alignment shown in left. Query protein Q5SNV9 colored as red in alignment, homolog Q95KD7 colored as blue. Query protein Q5SNV9 is also shown in right top, homolog Q95KD7 showed in right bottom. They are colored based on secondary structures. 

  Q5SNV9 MTRMSCPWGSYQWEPGACPAAPRGIGGGDMAGGIPDVRGLQEAALGAGRSQEEARLVEEAQTPVML--PQDSGQRVEEVPGDLMAKRMSLILHVQKLPWD 98
  Q95KD7 ----------------------------------------------------------------MLMAPQ--G-R------SSSKKRMGL----NR--WK 21

  Q5SNV9 HVPCLRRTRQNLYQDVGGHAHG-SGL-GGAKR--GAARSAL------R-RPLPPATCR-PAGIVSG--PSPRLDSNPTGAH--LIKQTRPLTVEWTKDTP 182
  Q95KD7 -----RFTRKPSPQ----HAFGPDNVEHWIKRVEKASEFAVSNAFFTRNSDLP----RSPWGQITDWKTSEQIED-----HDEIYAEAQELVNDWL-DSK 102

  Q5SNV9 VPEPMELRSD--ASHKENVSPKPAALPKPGKRLKQRRFRRSLGIGLSGRHDQWVPGCQVERGGPAATPSPGAVLDQEPCRVQTNLASPGPRLGLALKDTT 280
  Q95KD7 LKQ--ELASDEEGDAKNTVS-SVSLVPEANDHLKYDKF-----------DD--L--C----G----------YLEEE--EESTTVQKFIDHL-LH-K--- 163

  Q5SNV9 GQLVNSSFWQQSNLQSLARR-RQGKAREFAIQQSNLSINETSSPHLCPEPGGSSGPHK-LPWGPLLSQEPLA--RPSSCLRQSGLPAPGTPSGDFRPTEA 376
  Q95KD7 -NVVDSAV-----MEDLGRKENQDKK-----QQ--------KDPRLTME-----MRHKQVKENRLRREKELEYQRIQKTLKKS----------------A 223

  Q5SNV9 FAPLDGHTQPGLRSWGGLGSWRSRLVGEPLTLEDLAVPSQNQTQAPSRAAVHQLLASVHCLAQEAARLRCQAPQEPPAWGVSPKQKGEEGA--PRERVHR 474
  Q95KD7 F--LEAQC---L-----VQEEKKR-----KALE--AKKEEEEIQ---REMVK--------LRREIIERR-RTVKE--AWKI-EKKRQEENSQNSSEKLMF 291

  Q5SNV9 EEERTAFH-LSDTVPASSASKNKAQNI---TAPESEAICWQLLSRCFRSWRHLVKRQREPAAAAVALGR------WQLLRKCLQALWLREAQLEAAWGQY 564
  Q95KD7 --QST--HILLDEEKMAKERKRKLKELLIQIFKENQQ-C-Q--KRYFSAWHKLILDHR------IKLGKAGTLSDWKIQLKVLRA-W-RD---------Y 366

  Q5SNV9 TKVLLVRSFREVSGLQVGPGGRVKQC-PGSLREEEIAQRLLSHPRQRTDSRHERVQILQALQLAVFFLWCQQK--KRA--------RQERETLRKAT--- 650
  Q95KD7 T-----RSQK----LQ-----RETQALENDLREE---NR-----KQQLAAEHNRKQVLRHC-FTEWQHWCGAELLKRELALTKEENRKKMDALLKAASLG 443

  Q5SNV9 --RATQRTG-SFPQAWHSTAAGVAWVAPLSPQHQRAWLCRCFG---A----WQQFVQRGSRYRD-HLA---DRRTGTLRKCLEQWVRMKQLRESDGAK-- 734
  Q95KD7 KLSASESSGISLPE--EATAV----VGP--PVRN--------GQVTAVPPLWEK-PPLGS--SDCMLSPPLGRTTGNLQGSLQN-V---PLS-APGNKQH 519

  Q5SNV9 VTQLSL-CRQKAG-REAVYT----AGPGACGLGAV-GQAQGQQ---EQGRGSLQDACWTLALCWALLLWK-MRLFQRQWA---NSFFQGLQQRMLQRSLR 820
  Q95KD7 KT-LGVEPPQLPGSNETLRTTSQKAEP-LC-LGHFHSRHVFQQQLIEKQKKKLQEQQKTI-----LELKKNQRLAEAQWAAEHASAVTDTQSHLLSKP-R 610

  Q5SNV9 WWHLRALGPDATSSC---TKTPSALEPLSSSTLQDS---LEKVPRAP-TL--PDTLQGSLLWAAGQRQQGQCLL-----------LWQARAQQFQGTAR- 899
  Q95KD7 -------GEEEPRTCQMLVNSPVA-SPGTEGSRSDSRNCLSGRKRKPKQLMTPHPILKAMEERAIQRAERRRILAEKKKKQEEEKLAQLKAQEEERQKRE 702

  Q5SNV9 ------WYQHTR-QRRIF----LSWSRWATAQWAWRELAS-HRAWDRTCRAVL----GL--WRQRLL--QSRL-VEWWAQERGW--RLARDALCHWHSCW 976
  Q95KD7 AEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEH--YE----GVLLRKKGLEPW--KILRMQSKQNVQ-VAEEH-YCLFLQRKYLLTWFQC- 791

  Q5SNV9 QGQQFLHEK-CQTWVQVHLQGLQKVVFRSW-Q-----QAAAHQRCTVTRPEQLLLQSYFQAWCEVVR----DT-G--VLRAQHQAFQDGLRRRALGAVFA 1062
  Q95KD7 -SQESLARKMAQA-DQFYSQILLKRVIRSWLQYMTDLQEEVRKFC--VR---FLQKKIFRAWFNMVREVKIDSRGKHEIAAEH---SD---RRILWITFR 878

  Q5SNV9 TWREAQEVAAGAQEQRVAQASLARWRSCGQQGQEDGQQKKARAPQAFPAWPVAPGMHHEAQQQAGESAGAQAAQCWTWCWA----LWVHESCRGQVSRAH 1158
  Q95KD7 TWKKFVKF---MKEERVKE---ER-R---QQ-----LRRKVV--EILPDFQV-PGSDHELYQQSD-----------TWSLSKTSLL-------------- 935

  Q5SNV9 ASWKPRAWVLEASVQSAVRGGVQRAILTQLRPAELRRFLRTVQLRVRLGLPGAGKTRSCWTQATELVPPAPSLQCSLGGRRKPRGTAWAQRCREHSLCPA 1258
  Q95KD7 ---------------------------------------------------------------------------------------------------- 935

  Q5SNV9 FQLWPQWPGQSSWVPGLPLWTRDQGPRAHSSPEPRACKAQSKAHKRRLRILEKQAQAHGSALLLALKGHDALGHQEEVPAAPVPRGTASRAAGFPAGQVP 1358
  Q95KD7 ---------------------------------------------------------------------------------------------------- 935

  Q5SNV9 GSGMAALGGCPRGRAAGADPAQGVAPEMGLADVVAADPATASGSAVTAAGRWAFKKWHQRLAARSPRRGAASSPRPWSKPGPKGPESGQEAARAPRGWGL 1458
  Q95KD7 ---------------------------------------------------------------------------------------------------- 935

  Q5SNV9 GAEHGAQLQL 1468
  Q95KD7 ---------- 935

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:1903087 mitotic spindle pole body duplication
2. P GO:0000086 G2/M transition of mitotic cell cycle
2. P GO:0030474 spindle pole body duplication
2. P GO:0000922 spindle pole
2. P GO:0051301 cell division
2. P GO:0061496 half bridge of mitotic spindle pole body
2. P GO:0035974 meiotic spindle pole body
2. P GO:0044732 mitotic spindle pole body
2. P GO:0051225 spindle assembly
2. P GO:0005825 half bridge of spindle pole body

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q5SNV9 Uncharacterized protein C1orf167 0 2.00e-143 0.0
2. P O13652 Protein sfi1 2.91e-03 2.09e-07 NA
2. P Q3UI66 Coiled-coil domain-containing protein 34 1.90e-01 5.40e-03 NA
2. P Q12369 Protein SFI1 1.66e-02 1.56e-03 NA
3. B Q95KD7 Coiled-coil domain-containing protein 191 2.76e-03 NA 0.004