Summary

Q5T1N1

Homolog: Q8WP21.
Function: Protein AKNAD1.

Statistics

Total GO Annotation: 65
Unique PROST Go: 55
Unique BLAST Go: 1

Total Homologs: 24
Unique PROST Homologs: 21
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 1. PB was Q8WP21 (Protein AKNAD1) with a FATCAT P-Value: 0.000233 and RMSD of 12.89 angstrom. The sequence alignment identity is 79.5%.
Structural alignment shown in left. Query protein Q5T1N1 colored as red in alignment, homolog Q8WP21 colored as blue. Query protein Q5T1N1 is also shown in right top, homolog Q8WP21 showed in right bottom. They are colored based on secondary structures. 

  Q5T1N1 MDEADFSEHTTYKQEDLPYDGDLSQIKIGNDYSFTSKKDGLEVLNQIIFIADDPQEKAMHSETCGNTAVTIPLGKITENAANKKDEKEKQCTAALHIPAN 100
  Q8WP21 MDEADFSEDTTYKQEDLPYDGDLSPIKICNDYSFTSKNDAFEVSSQIIFIADDPQEKAMHNETCGNTAMTMPLGKTTENAANKKDEKEKQCTAALHIPAN 100

  Q5T1N1 EGDASKSSISDILLHHLSKEPFLRGQGIDCETLPEISNADSFEEEAIIKSIISCYNKNSWPKEQTPELTDQLNPKRDGENSNKPGSATTTEENTSDLEGP 200
  Q8WP21 EGDASKSSISDILLHHLSKEPFLRGQGIDCETLPEISNADSFEEEAIIKSIISCCNKNSWPKEQTLELTDQLNPKKDGENSNKPGSPTMTEENTSDLEET 200

  Q5T1N1 VAAGDSSHQENVNVLTKTKGPGDKQKSYQGQSPQKQQTEKANSGNTFKYGQGQVHYQLPDFSKIAPKVKIPKNKIINKPLAIAKQASFSSKSRDKPTLVQ 300
  Q8WP21 VAAGDSSHQENVNILTKTKGPGDKQNSYQGQAPPKQHTEKASSGNRFKYGQGQVHYQLPDFSKIAPEVKNPKNNIINKPLAIAKQVSF-SKLREKPAVVQ 299

  Q5T1N1 DSLETTPESNCVEKQHQEQKGKITEPSQQIQMEPIVHIHQELLTGIESEASLSKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVQEFSK 400
  Q8WP21 DILETMPESNCVEKQHQEQKGEITEPSQQIQMEPTVHIHQELLTGIESEASISKLSPTSQKGTSSSSSYIFQKISQGKQMCQKLKEQTDQLKTKVREFSK 399

  Q5T1N1 RIKQDSPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHESTIVGDFDPERKVEGEIFKLEMLLEDVKEKMDESKYTSAPSLPVSSPVTLD 500
  Q8WP21 RIKQESPYHLQDKKLVLEKLQGHLELLEQNFLATKDKHLTLQQQVHKHESTIVSDFDPERKVEGEIFKLEMLLEDVKDKVDESKYTSAPSLPVSSPVTLD 499

  Q5T1N1 DLASTFSSLSNEIPKEHPGHPSGPRGSGGSEVTGTPQGGPQEAPNEELCELAPQTYLNGHYGDAAAQNKPDQVAMRLSSNSGEDPNGTPRRQDCAEMTAP 600
  Q8WP21 DLASTSSSLSNEVPEEHPGHPPGPRGSGGSEATGTPQGGPQEAPKEELCELTPQIYLNGHYGDATVQNQPDQVAMRLSSNSGEDPRCTPGRQDCAETTAP 599

  Q5T1N1 SPSCAFCRRLLEWKQNVEKKGHGRINCGRFSIVLHEKAPHSDSTPNSDTGHSFCSDSGTEMQSNKCQDCGTKIPTSRRACRKEPTKEFHYRYNTPGQNYS 700
  Q8WP21 SPSCAFCRRLLEWKPKVEKKGHRRIHCGRFS-TVHEKAPHSDSTPNSDTGHSFCSDSGTEMQGNKCQDCGTKIPTSRRACRKEPPKEFHYRHNTPGENYS 698

  Q5T1N1 NHSKRGAFVQPHSLDESKNSSPSFLKPKRICSQRVNSKSFKGEHEPTPGKKKLQAFMTYSSD--PATPSPHFYSCRISGSKSLCDFDSTEEIKSEILNSA 798
  Q8WP21 NHSKRGAFVRPHSLHESKNSSPSLASP--FC---------------CPG---L---M-YSPDTSKSSPTPGWQEAEL-G---L------ENMKSQ----- 759

  Q5T1N1 LDHALRTATILKETTDQMIKTIAEDLAKAQRWRNRLKY 836
  Q8WP21 -------------------------------------- 759

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
1. PB GO:0021849 neuroblast division in subventricular zone
1. PB GO:0060232 delamination
1. PB GO:0050727 regulation of inflammatory response
1. PB GO:0005813 centrosome
1. PB GO:0001837 epithelial to mesenchymal transition
1. PB GO:0001650 fibrillar center
1. PB GO:0005874 microtubule
1. PB GO:0005814 centriole
1. PB GO:0060234 neuroblast delamination
2. P GO:0007317 regulation of pole plasm oskar mRNA localization
2. P GO:0009826 unidimensional cell growth
2. P GO:0071539 protein localization to centrosome
2. P GO:0006906 vesicle fusion
2. P GO:0006903 vesicle targeting
2. P GO:0046599 regulation of centriole replication
2. P GO:0005819 spindle
2. P GO:0009909 regulation of flower development
2. P GO:0034451 centriolar satellite
2. P GO:2000028 regulation of photoperiodism, flowering
2. P GO:0051310 metaphase plate congression
2. P GO:0023052 signaling
2. P GO:0010119 regulation of stomatal movement
2. P GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway
2. P GO:0007338 single fertilization
2. P GO:0019094 pole plasm mRNA localization
2. P GO:0008017 microtubule binding
2. P GO:0007052 mitotic spindle organization
2. P GO:0051382 kinetochore assembly
2. P GO:0061493 central plaque of mitotic spindle pole body
2. P GO:0090307 mitotic spindle assembly
2. P GO:0006997 nucleus organization
2. P GO:0002376 immune system process
2. P GO:0035577 azurophil granule membrane
2. P GO:0044732 mitotic spindle pole body
2. P GO:1990498 mitotic spindle microtubule
2. P GO:0005815 microtubule organizing center
2. P GO:0051301 cell division
2. P GO:0051642 centrosome localization
2. P GO:0009585 red, far-red light phototransduction
2. P GO:0031616 spindle pole centrosome
2. P GO:0080025 phosphatidylinositol-3,5-bisphosphate binding
2. P GO:0009908 flower development
2. P GO:0007098 centrosome cycle
2. P GO:0007079 mitotic chromosome movement towards spindle pole
2. P GO:0007346 regulation of mitotic cell cycle
2. P GO:0000922 spindle pole
2. P GO:0045450 bicoid mRNA localization
2. P GO:0043325 phosphatidylinositol-3,4-bisphosphate binding
2. P GO:0021762 substantia nigra development
2. P GO:0008595 anterior/posterior axis specification, embryo
2. P GO:0070840 dynein complex binding
2. P GO:0048578 positive regulation of long-day photoperiodism, flowering
2. P GO:0140475 spindle pole body anchor activity
2. P GO:0005694 chromosome
2. P GO:0070652 HAUS complex
2. P GO:0045842 positive regulation of mitotic metaphase/anaphase transition
2. P GO:0048576 positive regulation of short-day photoperiodism, flowering
2. P GO:0009733 response to auxin
2. P GO:0048573 photoperiodism, flowering
2. P GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
2. P GO:0010031 circumnutation
2. P GO:0032266 phosphatidylinositol-3-phosphate binding
2. P GO:0051225 spindle assembly
2. P GO:0005635 nuclear envelope
3. B GO:0043231 intracellular membrane-bounded organelle

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q8WP21 Protein AKNAD1 2.33e-04 7.55e-49 0.0
1. PB Q5T1N1 Protein AKNAD1 0 3.60e-152 0.0
1. PB Q7Z591 Microtubule organization protein AKNA 1.89e-01 8.11e-10 2.65e-05
2. P Q15398 Disks large-associated protein 5 3.79e-02 8.37e-03 NA
2. P Q657D6 ELF3-like protein 2 1.28e-01 7.16e-04 NA
2. P Q8NE31 Protein FAM13C 1.01e-01 6.31e-03 NA
2. P Q66JV7 Uncharacterized protein C8orf58 homolog 4.28e-01 1.65e-02 NA
2. P Q9SNQ6 Protein HEADING DATE 3B 6.32e-02 2.64e-02 NA
2. P Q80VW7 Microtubule organization protein AKNA 1.34e-01 5.02e-08 NA
2. P Q9D786 HAUS augmin-like complex subunit 5 2.53e-01 2.30e-02 NA
2. P Q60664 Inositol 1,4,5-triphosphate receptor associated 2 3.59e-02 4.20e-09 NA
2. P Q8K2J4 Coiled-coil domain-containing protein 14 6.62e-01 5.45e-06 NA
2. P Q9U9I5 Protein swallow 1.98e-01 2.23e-02 NA
2. P Q12912 Inositol 1,4,5-triphosphate receptor associated 2 1.16e-01 8.16e-08 NA
2. P Q9H4M7 Pleckstrin homology domain-containing family A member 4 1.22e-01 7.12e-03 NA
2. P Q9DA21 Single-pass membrane and coiled-coil domain-containing protein 2 1.01e-01 4.90e-04 NA
2. P A6H5Y1 M-phase phosphoprotein 9 1.94e-01 1.69e-06 NA
2. P Q5REU9 Protein ITPRID2 1.30e-01 5.47e-03 NA
2. P Q5RKG1 Spindle and centriole-associated protein 1 1.58e-01 1.52e-02 NA
2. P O82804 Protein EARLY FLOWERING 3 2.85e-02 1.01e-02 NA
2. P Q49A88 Coiled-coil domain-containing protein 14 5.08e-01 1.09e-03 NA
2. P Q8C804 Spindle and centriole-associated protein 1 2.55e-01 4.15e-02 NA
2. P Q10218 Spindle pole body protein ppc89 6.79e-02 1.18e-02 NA
2. P P40688 Protein swallow 8.29e-02 5.83e-04 NA