Summary

Q5T4H9

Homolog: P59021.
Function: Down syndrome critical region protein 9.

Statistics

Total GO Annotation: 7
Unique PROST Go: 3
Unique BLAST Go: 4

Total Homologs: 14
Unique PROST Homologs: 12
Unique BLAST Homologs: 1

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was P59021 (Down syndrome critical region protein 9) with a FATCAT P-Value: 0.0398 and RMSD of 3.13 angstrom. The sequence alignment identity is 26.1%.
Structural alignment shown in left. Query protein Q5T4H9 colored as red in alignment, homolog P59021 colored as blue. Query protein Q5T4H9 is also shown in right top, homolog P59021 showed in right bottom. They are colored based on secondary structures. 

  Q5T4H9 MQSREPSGWRTAE-RRRGWRCRGVP-TPSGD-------RG---------PGAARPAA--RG-----GA---GETT--GQ----QRPLQV---PGASAAAA 63
  P59021 ------MG-RICPVNSRARRLRARPGRPSGDSLPYHQLQGGAPRLWSPDPG--RPAAYRRAHVCDVTAPRWGSTSRQGEGAVLQRMLRRRAPPSWSRDHA 91

  Q5T4H9 RTRLLR-WHH-RVPSPRATRSPGSIRRTSPCSGGPDRPERPECADACCYLLDP-FTLPLI----QDFFRGCAASDFDRRD 136
  P59021 YSR--RGWENVALFLNRKRKQEGT-ENTSICC-------RPESALACGGNLSPQFLKKVIQIQTQELW------------ 149

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0000122 negative regulation of transcription by RNA polymerase II
2. P GO:0006470 protein dephosphorylation
2. P GO:0097677 STAT family protein binding
3. B GO:0015920 lipopolysaccharide transport
3. B GO:0043165 Gram-negative-bacterium-type cell outer membrane assembly
3. B GO:0009279 cell outer membrane
3. B GO:0010033 response to organic substance

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q5T4H9 Putative uncharacterized protein encoded by MIR1915-HG 0 2.21e-164 2.06e-92
2. P P0DP75 Putative uncharacterized protein MED14OS 5.10e-02 1.93e-04 NA
2. P Q8N7S6 Uncharacterized protein ARIH2OS 6.44e-02 1.37e-02 NA
2. P Q6XXX2 Putative uncharacterized protein encoded by LINC00114 6.61e-01 1.41e-02 NA
2. P P21601 Uncharacterized protein IRL14 NA 2.63e-02 NA
2. P P59021 Down syndrome critical region protein 9 3.98e-02 1.97e-03 NA
2. P Q8N9T2 Putative uncharacterized protein CXorf42 1.36e-01 3.98e-03 NA
2. P P34245 Uncharacterized protein YKL097C 7.14e-01 3.65e-02 NA
2. P Q569G3 Uncharacterized protein C5orf47 6.34e-02 3.84e-02 NA
2. P B1ANY3 Putative protein FAM220BP 2.71e-01 4.32e-04 NA
2. P Q01480 Putative uncharacterized protein M2 (Fragment) NA 4.95e-02 NA
2. P P03164 Putative uncharacterized 15.3 kDa protein NA 2.13e-02 NA
2. P P0C879 Putative uncharacterized protein FLJ43185 4.32e-02 6.36e-05 NA
3. B A5VXJ8 LPS-assembly protein LptD 9.14e-01 NA 0.018