Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PB was
A1L443
(NUT family member 2F) with a FATCAT P-Value: 1.09e-05 and RMSD of 13.18 angstrom. The sequence alignment identity is 97.2%.
Structural alignment shown in left. Query protein Q5VZR2 colored as red in alignment, homolog A1L443 colored as blue.
Query protein Q5VZR2 is also shown in right top, homolog A1L443 showed in right bottom. They are colored based on secondary structures.
Q5VZR2 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPSPGPTHRPPLVTAVVPPAGPLVLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTL 100 A1L443 MASNGAYPVLGPGVTVNPGTSLSVFTALPFATPAPGPAHRPPLVTAVVPPAGPLVLSAFPSTPLVAGQDGRGPSGAGASNVFVQMRTEVGPVKPPQAQTL 100 Q5VZR2 ILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNAGPWPQGAHGEGSLAPSQAKARPDDS 200 A1L443 ILTQAPLVWQAPGTLCGGVMCPPPLLLAAAPGVPVTSAQVVGGTQACEGGWSHGLPLPPPPPAAQVAPIVSPGNARPWPQGAHGEGSLAPSQAKARPDDS 200 Q5VZR2 CKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRMIFYEMAAKFLEFEAEEEMQIQKSQWMK 300 A1L443 CKPKSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWQAMREWQHTSNFDRMIFYEMAEKFLEFEAEEEMQIQKSQWMK 300 Q5VZR2 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRP--P-------------RPAETKVPEEIPPEVVQEYVD 385 A1L443 GPQSLPPPAPPRLEPRGPPAPEVVKQPVYLPSKDGPKAPTACLPPPRPQRPAETKAHLPPPRPQRPAETNAHLPPPRPQRPAETKVPEEIPPEVVQEYVD 400 Q5VZR2 IMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGMTSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKR 485 A1L443 IMEELLGSHPGDTGEPEGQREKGKVEQPQEEDGITSDPGLLSYIDKLCSQEDFVTKVEAVIHPRFLEELLSPDPQMDFLALSQELEQEEGLTLAQLVEKR 500 Q5VZR2 LLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHR 585 A1L443 LLSLKEKGCGRAAPRHGTARLDSSPSEFAAGQEAAREVPDPQQRVSVETSPPQTAAQDPQGQGRVRTGMARSEDPAVLLGCQDSPRLKAVRPTSPPQDHR 600 Q5VZR2 PTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPVPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRP 685 A1L443 PTCPGLGTKDALGLPGESPVKESHGLAKGSSEETELPGMVYVVGSHHRLRPWRLSQSPVPSSGLLSPGGRGPQGALQSPSAQKRGLSPSPSPASKSKKRP 700 Q5VZR2 LFGSPSPAEKTPHPGPGLRVSGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ 741 A1L443 LFGSPSPAEKTPHPGPGLRVSGEQSLAWGLGGPSQSQKRKGDPLASRRKKKRHCSQ 756
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
| Source | GO | Description |
|---|---|---|
| 1. PB | GO:0005634 | nucleus |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
| Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
|---|---|---|---|---|---|
| 1. PB | Q86Y26 | NUT family member 1 | 7.71e-02 | 3.18e-07 | 1.27e-128 |
| 1. PB | Q5VZR2 | NUT family member 2G | 0 | 1.51e-139 | 0.0 |
| 1. PB | Q8BHP2 | NUT family member 1 | 1.30e-03 | 3.84e-05 | 3.48e-116 |
| 1. PB | Q3V0C3 | NUT family member 2 | 4.90e-04 | 1.75e-34 | 6.24e-140 |
| 1. PB | Q5VT03 | NUT family member 2D | 3.26e-03 | 1.43e-55 | 0.0 |
| 1. PB | A1L443 | NUT family member 2F | 1.09e-05 | 1.14e-88 | 0.0 |
| 1. PB | Q8IVF1 | NUT family member 2A | 5.96e-05 | 3.97e-23 | 0.0 |
| 1. PB | A6NNL0 | NUT family member 2B | 2.15e-04 | 1.44e-23 | 0.0 |
| 1. PB | B1AL46 | NUT family member 2E | 4.95e-04 | 4.90e-24 | 0.0 |