Summary

Q63HN1

Homolog: Q6ZU69.
Function: Protein FAM205A.

Statistics

Total GO Annotation: 15
Unique PROST Go: 8
Unique BLAST Go: 7

Total Homologs: 16
Unique PROST Homologs: 2
Unique BLAST Homologs: 13

Structures and Sequence Alignment

The best structural homolog that predicted by 3. B was Q6ZU69 (Protein FAM205A) with a FATCAT P-Value: 0.00168 and RMSD of 9.50 angstrom. The sequence alignment identity is 41.1%.
Structural alignment shown in left. Query protein Q63HN1 colored as red in alignment, homolog Q6ZU69 colored as blue. Query protein Q63HN1 is also shown in right top, homolog Q6ZU69 showed in right bottom. They are colored based on secondary structures.

  Q63HN1 ---------------------------------------------------------------------------------------------------- 0
  Q6ZU69 MLSPTFVLWEVGYPLYIYGSIFIVIVIIWQVKRSHHELSSEPKRSCCRCHQKVRQRARDAASTARRRSREEAEKPQKLLSIIKSQGWLPLERSVRRILCA 100

  Q63HN1 ---------------------------------------------------------------------------------------------------- 0
  Q6ZU69 DPCCQICNSVALEIQQLLVGENNQISLTLSGPLQGSSCLEMLSTSSMSLDQSLEFHSWHTRELSLSSVTPTLSQLTDQKSLTQSAAQSTYADGIQDYWAD 200

  Q63HN1 ----------------------------------------------------------------------MHPMALHMVLPAHLPFLSPEVLRLLEVHVK 30
  Q6ZU69 HLQLGQEFQVPDVLRGPNTIASSRIEKPRAPLNQEEMTQSNPSLVQGNQGQHHLNSQVSLLSLNPETLNRMHPMALHMVLPAHLPFLSPEVLRLLEVHVK 300

  Q63HN1 KWMHFQRWGLPRRVEESLRQLMPNPPLYYQPGNDQPVSFNLNNTSQVSLHRSETISLQTWCSCVAGQPIQTFWVSEWSTMNPEQRHHCQQTPNPMALALP 130
  Q6ZU69 KWMHFQRWGLPRRVEESLRQLMPNPPLYYQPGNDQPVSFNLKNTPQVSLHRFETISLQTWCSCVAGQPIQTFWVSEWSTMNPEQRHHCQQTPNPMALALP 400

  Q63HN1 SPALKALSGPHPQSGGQDNDSGSDLQQKYSQLFCGLPSLHSESLVATFMGSQGLPKIENVPKPPLKDPFLFNDLSFPQLLPKTSPQSAPPSSPLSPNWVS 230
  Q6ZU69 SPALKALSGPHPQSGGQDNDSGSDLQQKYSQLFCGLPSLHSESLVATFMGSQGLPKIENVPKPPLKDPFLFNELSFPQLLPKTSPQSAPPSSPLSPNWMS 500

  Q63HN1 PSDHQRAQINVPFLTLAEYEALEWHLLQRQLQLQWGWPAALQRSQHTQCLMQHEPCGKAQSPETTTASQTGKSISVLTRELLFFPEHARKLLEFHIQKQS 330
  Q6ZU69 PSDHQRAQINVPFLTLAEYEALEWHLLQRQLQLQWGWPAALQRSQHTQCLMQHEPCGKAQSPETTTASQTGKSISVLTRELLFFPEHARKLLEFHIQKQL 600

  Q63HN1 IRHRWGLPQKIQQSIQLLLTSTDQQTVSSSSTALANVSIPQPVALEANGACDVLSPIAAPVSIPRPHLLTQVKAILQSHIDSKCGQIHQGKIPACVHRSW 430
  Q6ZU69 IRHRWGLPQKIQQSIQLLLTSTDQQTVSSSSTALANVSIPQPVALEANGACDVLSPIAAPVSIPRPHLLTQVKAILQSHIDSKCGQIHQGKIPACVHRSW 700

  Q63HN1 DCRISGVLAVAPFPCIPESQFLVLQTASDPDLHHKVMPWMPTALDQQQQALPGTVTEHPKLLRVLSVEAIEKLETTLRHKHLAFLSGLPALYYVALPRAL 530
  Q6ZU69 DCRISGVLAVAPFPCIPESQFLELQTASDPDLHHKVMPWMPTALDQQQQALPGTVTEHPKLLRVLSVEAIEKLETTLRHKHLAFLSGLPALYYVALPRAL 800

  Q63HN1 APAVTSQSVITEMEPSPVEIPAEPLI-------------------------------------------------------------------------- 556
  Q6ZU69 APAVTSQSVITEMEPSPVEIPAEPLIQMVSFEEQCISLGPCPQGNNESCTDVAKEFQPAVPVKGTMETLPLESQTHPTSPHSLQTHILTKLNFHLRKKVL 900

  Q63HN1 ---------------------------------------------------------------------------------------------------- 556
  Q6ZU69 EIQWGIPIRARKSREQTVAAPENISTQKSLESLNHQGETLLQELPIPPDTLPAPNPEGVHLKEQLANDLKAVQQNQKQSNSKAVPQGSAHSVSKISQPSG 1000

  Q63HN1 ---------------------------------------------------------------------------------------------------- 556
  Q6ZU69 DMTEAHMPCVQVEANVNKPSLEEPCGPEPQSPSKSKDPAHVPMLAGNREDPEETKAARDHREGDAGFGRSSTREERRPAEDQRPAGMLPNKTPRGSWRWS 1100

  Q63HN1 ---------------------------------------------------------------------------------------------------- 556
  Q6ZU69 RSFHLADPCQHSPQHHPQLKLPQLPPRVPGEKESEKDLQDSQTKLTVILEPATIPENAQTVLPQASQGQPFLSQPTQAKPLQGQTLQGQVLHGLVMPVHA 1200

  Q63HN1 ---------------------------------------------------------------------------------------------------- 556
  Q6ZU69 QKKPSLTESSFRNKIKCFLQHINPKTKGKGHEDSMFSAAAKVAKTRKENVAKSLAPAKSPVGRSKTEKPTGCSKAQSRPAQKLVGPAFLDGPQSLDDKLR 1300

  Q63HN1 ----------------------------------- 556
  Q6ZU69 LHSRQPGSASALGYPRHCPRHCPREACANKPGHPT 1335

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0036126 sperm flagellum
2. P GO:0008017 microtubule binding
2. P GO:0034453 microtubule anchoring
2. P GO:0030246 carbohydrate binding
2. P GO:0005879 axonemal microtubule
2. P GO:0005814 centriole
2. P GO:0036064 ciliary basal body
2. P GO:0005856 cytoskeleton
3. B GO:0001669 acrosomal vesicle
3. B GO:0030154 cell differentiation
3. B GO:0016021 integral component of membrane
3. B GO:0003779 actin binding
3. B GO:0043160 acrosomal lumen
3. B GO:0002080 acrosomal membrane
3. B GO:0007283 spermatogenesis

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q63HN1 Putative protein FAM205B 0 3.04e-159 0.0
2. P Q9FNM2 Jacalin-related lectin 45 9.72e-01 4.26e-02 NA
2. P Q8BQB6 Stabilizer of axonemal microtubules 2 3.27e-01 1.16e-02 NA
3. B Q6ZU69 Protein FAM205A 1.68e-03 NA 0.0
3. B P0C874 Spermatogenesis-associated protein 31D3 8.51e-02 NA 3.68e-12
3. B E9QAF0 Spermatogenesis-associated protein 31 7.28e-01 NA 4.64e-08
3. B C0HKD1 Protein FAM205A-2 4.14e-01 NA 1.18e-163
3. B Q5TZJ5 Spermatogenesis-associated protein 31A1 7.52e-01 NA 1.73e-05
3. B Q5VYP0 Spermatogenesis-associated protein 31A3 3.78e-01 NA 2.08e-05
3. B C0HKD3 Protein FAM205A-4 1.99e-01 NA 1.18e-163
3. B Q5VVP1 Spermatogenesis-associated protein 31A6 5.02e-01 NA 3.38e-06
3. B Q6ZQQ2 Spermatogenesis-associated protein 31D1 3.66e-01 NA 7.65e-13
3. B Q5VYM1 Uncharacterized protein C9orf131 7.64e-01 NA 0.004
3. B C0HKD2 Protein FAM205A-3 3.37e-01 NA 1.18e-163
3. B B6VQA5 Spermatogenesis-associated protein 31 6.49e-01 NA 2.24e-04
3. B Q6ZUB0 Spermatogenesis-associated protein 31D4 5.13e-01 NA 3.68e-12