Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 2. P was
P0DKH9
(Auxin-responsive endogenous peptide 1) with a FATCAT P-Value: 0.0112 and RMSD of 1.06 angstrom. The sequence alignment identity is 20.4%.
Structural alignment shown in left. Query protein Q6NUR6 colored as red in alignment, homolog P0DKH9 colored as blue.
Query protein Q6NUR6 is also shown in right top, homolog P0DKH9 showed in right bottom. They are colored based on secondary structures.
Q6NUR6 MEEGNNNEEVIH-LNNFHCHRGQDFVI----FFW-KTQIIQREKTESL- 42 P0DKH9 M--G-LSDCLIYRL-VVRCF--LDYSICAPFYFYHKFML---SASEPVF 40
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
| Source | GO | Description |
|---|---|---|
| 2. P | GO:0010930 | negative regulation of auxin mediated signaling pathway |
| 2. P | GO:0048364 | root development |
| 2. P | GO:0009507 | chloroplast |
| 2. P | GO:0009734 | auxin-activated signaling pathway |
| 3. B | GO:0099546 | protein catabolic process, modulating synaptic transmission |
| 3. B | GO:0098978 | glutamatergic synapse |
| 3. B | GO:0098685 | Schaffer collateral - CA1 synapse |
| 3. B | GO:0006915 | apoptotic process |
| 3. B | GO:0032480 | negative regulation of type I interferon production |
| 3. B | GO:0061630 | ubiquitin protein ligase activity |
| 3. B | GO:0050691 | regulation of defense response to virus by host |
| 3. B | GO:0070936 | protein K48-linked ubiquitination |
| 3. B | GO:0032648 | regulation of interferon-beta production |
| 3. B | GO:0043161 | proteasome-mediated ubiquitin-dependent protein catabolic process |
| 3. B | GO:0098843 | postsynaptic endocytic zone |
| 3. B | GO:0005654 | nucleoplasm |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
| Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
|---|---|---|---|---|---|
| 1. PB | Q6NUR6 | Putative protein RNF216-like | 0 | 5.77e-134 | 7.70e-25 |
| 2. P | Q96KT6 | Putative uncharacterized protein encoded by LINC00208 | 5.06e-01 | 2.90e-02 | NA |
| 2. P | P10428 | Uncharacterized immunity region protein 4 | NA | 9.65e-03 | NA |
| 2. P | P0DKH9 | Auxin-responsive endogenous peptide 1 | 1.12e-02 | 2.36e-03 | NA |
| 2. P | Q9MUM6 | Uncharacterized 7.4 kDa protein in ndhF-psbD intergenic region | 9.83e-02 | 3.36e-03 | NA |
| 2. P | P49828 | Uncharacterized 5.5 kDa protein in ccsA-rps6 intergenic region | 1.62e-03 | 1.89e-02 | NA |
| 2. P | Q83JS7 | Uncharacterized protein YqgB | 3.02e-02 | 3.29e-03 | NA |
| 2. P | O34405 | Uncharacterized protein YkzD | 6.69e-01 | 1.39e-03 | NA |
| 2. P | Q0T0V2 | Uncharacterized protein YqgB | 1.41e-02 | 3.29e-03 | NA |
| 3. B | P58283 | E3 ubiquitin-protein ligase RNF216 | 8.91e-01 | NA | 1.14e-06 |
| 3. B | Q9NWF9 | E3 ubiquitin-protein ligase RNF216 | 8.96e-01 | NA | 3.02e-10 |