Summary

Q6NVV0

Homolog: P10034.
Function: Gastrin.

Statistics

Total GO Annotation: 44
Unique PROST Go: 35
Unique BLAST Go: 9

Total Homologs: 39
Unique PROST Homologs: 32
Unique BLAST Homologs: 6

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was P10034 (Gastrin) with a FATCAT P-Value: 0.0484 and RMSD of 2.73 angstrom. The sequence alignment identity is 30.6%.
Structural alignment shown in left. Query protein Q6NVV0 colored as red in alignment, homolog P10034 colored as blue. Query protein Q6NVV0 is also shown in right top, homolog P10034 showed in right bottom. They are colored based on secondary structures. 

  Q6NVV0 MLLAAVGDDEL-TD-SEDESDLFHEELEDFYD-LDL 33
  P10034 -ELEPQGPPHLGTDLSKKQGP-WAEE-EAAYGWMDF 33

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0005509 calcium ion binding
2. P GO:0019076 viral release from host cell
2. P GO:0004563 beta-N-acetylhexosaminidase activity
2. P GO:0030500 regulation of bone mineralization
2. P GO:0032571 response to vitamin K
2. P GO:0046848 hydroxyapatite binding
2. P GO:0090729 toxin activity
2. P GO:0106329 L-phenylalaine oxidase activity
2. P GO:0044179 hemolysis in another organism
2. P GO:0032801 receptor catabolic process
2. P GO:0032094 response to food
2. P GO:0102148 N-acetyl-beta-D-galactosaminidase activity
2. P GO:0008284 positive regulation of cell population proliferation
2. P GO:1900076 regulation of cellular response to insulin stimulus
2. P GO:0008180 COP9 signalosome
2. P GO:0040029 regulation of gene expression, epigenetic
2. P GO:0034644 cellular response to UV
2. P GO:0008147 structural constituent of bone
2. P GO:0060348 bone development
2. P GO:0033644 host cell membrane
2. P GO:0005576 extracellular region
2. P GO:0005179 hormone activity
2. P GO:0001649 osteoblast differentiation
2. P GO:0009733 response to auxin
2. P GO:0008236 serine-type peptidase activity
2. P GO:0051220 cytoplasmic sequestering of protein
2. P GO:0005261 cation channel activity
2. P GO:0008810 cellulase activity
2. P GO:0042742 defense response to bacterium
2. P GO:2000435 negative regulation of protein neddylation
2. P GO:0042609 CD4 receptor binding
2. P GO:0000785 chromatin
2. P GO:0009734 auxin-activated signaling pathway
2. P GO:0031214 biomineral tissue development
2. P GO:0005654 nucleoplasm
3. B GO:0016567 protein ubiquitination
3. B GO:0003723 RNA binding
3. B GO:1990830 cellular response to leukemia inhibitory factor
3. B GO:0003682 chromatin binding
3. B GO:1990904 ribonucleoprotein complex
3. B GO:0061630 ubiquitin protein ligase activity
3. B GO:0046872 metal ion binding
3. B GO:0016740 transferase activity
3. B GO:0000209 protein polyubiquitination

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q6NVV0 Putative makorin-5 0 1.48e-163 2.29e-14
2. P Q6P6E6 COP9 signalosome complex subunit 9 1.38e-01 2.12e-05 NA
2. P P86315 Osteocalcin 2.90e-01 3.70e-02 NA
2. P P02819 Osteocalcin 2.67e-01 3.55e-02 NA
2. P Q8WXC6 COP9 signalosome complex subunit 9 2.16e-01 1.86e-06 NA
2. P P85512 Beta-hexosaminidase (Fragment) 4.35e-01 1.28e-03 NA
2. P P80936 Testis ecdysiotropin peptide 1 7.62e-01 1.81e-03 NA
2. P P86313 Osteocalcin 2.89e-01 3.70e-02 NA
2. P Q3U898 COP9 signalosome complex subunit 9 1.52e-01 5.15e-05 NA
2. P P0C8X1 Peptide 9797 (Fragment) 5.07e-01 1.60e-02 NA
2. P P0DMH5 Snake venom serine protease (Fragment) NA 6.47e-03 NA
2. P P08807 Protein Vpu (Fragment) NA 1.04e-02 NA
2. P P80349 Fuctinin-3 (Fragment) 1.45e-01 1.31e-02 NA
2. P P02821 Osteocalcin 2.32e-01 3.74e-02 NA
2. P P86531 Vipera russelli proteinase RVV-V homolog 2 (Fragment) NA 1.32e-02 NA
2. P P86535 L-amino-acid oxidase L1 (Fragment) 5.11e-01 9.45e-05 NA
2. P O29971 Uncharacterized protein AF_0268 5.61e-01 2.61e-02 NA
2. P Q6DDA3 COP9 signalosome complex subunit 9 3.80e-01 3.31e-05 NA
2. P P08808 Protein Vpu (Fragment) NA 1.02e-05 NA
2. P P80899 Protein C activator (Fragment) NA 1.32e-02 NA
2. P P0DJG5 Snake venom serine protease AHP-Ka (Fragment) NA 6.26e-03 NA
2. P P10034 Gastrin 4.84e-02 1.70e-02 NA
2. P P33714 Gastrin 4.09e-01 8.17e-05 NA
2. P C0HLV0 Endoglucanase gh5 (Fragment) 1.18e-01 4.08e-05 NA
2. P P83998 U14-ctenitoxin-Pn1a 8.46e-01 3.62e-02 NA
2. P A1L3P1 COP9 signalosome complex subunit 9 1.97e-01 8.90e-05 NA
2. P P08804 Protein Vpu (Fragment) NA 3.07e-05 NA
2. P P86314 Osteocalcin 2.90e-01 3.70e-02 NA
2. P Q32PD7 COP9 signalosome complex subunit 9 1.89e-01 1.86e-06 NA
2. P Q9T0H2 Small acidic protein 1 1.94e-01 2.72e-02 NA
2. P P0C2K6 Dermonecrotic toxin LgSicTox-beta-LOXN4 (Fragments) 4.99e-01 3.88e-03 NA
2. P K4JY29 Bottromycin D 1.75e-01 5.21e-03 NA
2. P P04564 Gastrin 1.33e-01 6.37e-04 NA
3. B Q5NU14 Probable E3 ubiquitin-protein ligase makorin-1 8.73e-01 NA 6.31e-07
3. B Q9QXP6 E3 ubiquitin-protein ligase makorin-1 9.19e-01 NA 2.18e-11
3. B Q9TT91 E3 ubiquitin-protein ligase makorin-1 9.34e-01 NA 4.29e-10
3. B Q4VBT5 Probable E3 ubiquitin-protein ligase makorin-1 8.20e-01 NA 2.77e-07
3. B Q13064 Probable E3 ubiquitin-protein ligase makorin-3 8.80e-01 NA 0.035
3. B Q9UHC7 E3 ubiquitin-protein ligase makorin-1 8.70e-01 NA 2.73e-11