Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 3. B was
P0CF75
(Endogenous Bornavirus-like nucleoprotein 1) with a FATCAT P-Value: 1.76e-12 and RMSD of 1.87 angstrom. The sequence alignment identity is 39.5%.
Structural alignment shown in left. Query protein Q6P2I7 colored as red in alignment, homolog P0CF75 colored as blue.
Query protein Q6P2I7 is also shown in right top, homolog P0CF75 showed in right bottom. They are colored based on secondary structures.
Q6P2I7 MGYFLKLYAYVNSHSLFVWVCDRSYKRSFRPMILNKIKELSRNQFSTMSHLRKDSQPSSPGDDAMDRSGLPDLQGRFELSGKNRQYPLDALEPQPSIGDI 100 P0CF75 -----------------------------------------------MSRPRNNPQTSSPQDSTKDGSSFHYFQGRFELSGKSRQYPADALEPQPGIGDV 53 Q6P2I7 KDIKKAAKSMLDPAHKSHFHPVTPSLVFLCFIFDGLHQALLSVGVSKRSNTVVGNENEERGTPYASRFKD-MPNFIALEKSSVLRHCCDLLIGIAAGSSD 199 P0CF75 KVIEKATKSMLDPAQRSHFYLVTPSLVFLCFIFDGLHKALLSVGVSKRSNIVIGNENKETGTLYASKFEDVLPTFTALEMSSILRHCCD-LIGIAAGSSD 152 Q6P2I7 KICTSSLQVQRRFKAMMASIGR-LSHGESADLLISCNAESAIGWISSRPWVGELMFTLLFGDFESP----LHKLR----KSS------------------ 272 P0CF75 PICTNSLQVQRQFKAMMISIGRPL-HSESADLLISYNAGPAIDWINSRPWVGGLMFTFLFGEFESPACELLDQVKVVASKAQMMTYYTVRMFLDQCVDGS 251 Q6P2I7 ---------------------------------------------------------------------------------------------------- 272 P0CF75 TALPAVVLEIPVFEQKKPLAKKVLGDFFEFGGVLRHPVIGVLSPQMFPNLATAANYWAKRRNSTFSGFEALDIIPGSTITFPVLQMASAQKISRGSDMDP 351 Q6P2I7 --------------- 272 P0CF75 YTLNILRGYGISGFE 366
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source | GO | Description |
---|---|---|
2. P | GO:0009792 | embryo development ending in birth or egg hatching |
2. P | GO:0005131 | growth hormone receptor binding |
2. P | GO:0015031 | protein transport |
2. P | GO:0005504 | fatty acid binding |
2. P | GO:0007019 | microtubule depolymerization |
2. P | GO:0000212 | meiotic spindle organization |
2. P | GO:0071630 | nuclear protein quality control by the ubiquitin-proteasome system |
2. P | GO:0005634 | nucleus |
2. P | GO:0008352 | katanin complex |
2. P | GO:0030276 | clathrin binding |
2. P | GO:0003997 | acyl-CoA oxidase activity |
2. P | GO:0031144 | proteasome localization |
2. P | GO:0032588 | trans-Golgi network membrane |
2. P | GO:0034080 | CENP-A containing chromatin assembly |
2. P | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase |
2. P | GO:0046907 | intracellular transport |
2. P | GO:0055088 | lipid homeostasis |
2. P | GO:0000922 | spindle pole |
2. P | GO:0000794 | condensed nuclear chromosome |
2. P | GO:0051013 | microtubule severing |
2. P | GO:0030121 | AP-1 adaptor complex |
2. P | GO:0001940 | male pronucleus |
3. B | GO:0042025 | host cell nucleus |
3. B | GO:0019055 | modification by virus of host cell cycle regulation |
3. B | GO:0019029 | helical viral capsid |
3. B | GO:0046718 | viral entry into host cell |
3. B | GO:0039592 | suppression by virus of G2/M transition of host mitotic cell cycle |
3. B | GO:0039644 | suppression by virus of host NF-kappaB cascade |
3. B | GO:0030430 | host cell cytoplasm |
3. B | GO:0019013 | viral nucleocapsid |
3. B | GO:0075732 | viral penetration into host nucleus |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
---|---|---|---|---|---|
1. PB | Q6P2I7 | Endogenous Bornavirus-like nucleoprotein 2 | 0 | 2.24e-137 | 0.0 |
2. P | Q9DAQ9 | Spermatogenesis-associated protein 19, mitochondrial | 8.56e-02 | 2.36e-02 | NA |
2. P | Q2UGF7 | Tethering factor for nuclear proteasome sts1 | 7.79e-02 | 3.82e-02 | NA |
2. P | A6R7I3 | Tethering factor for nuclear proteasome STS1 | 1.05e-01 | 1.14e-02 | NA |
2. P | P34006 | Somatotropin | 3.46e-02 | 4.00e-02 | NA |
2. P | Q1T763 | Centromere protein R | 1.85e-01 | 1.27e-03 | NA |
2. P | Q6CH63 | Tethering factor for nuclear proteasome STS1 | 1.28e-01 | 1.70e-02 | NA |
2. P | C0SIQ6 | Tethering factor for nuclear proteasome STS1 | 8.47e-02 | 9.07e-03 | NA |
2. P | Q0CLE0 | Tethering factor for nuclear proteasome sts1 | 1.45e-01 | 2.76e-02 | NA |
2. P | P69614 | Protein I | NA | 5.23e-03 | NA |
2. P | B8N9X2 | Tethering factor for nuclear proteasome sts1 | 1.01e-01 | 3.82e-02 | NA |
2. P | C5GE44 | Tethering factor for nuclear proteasome STS1 | 9.45e-02 | 1.42e-02 | NA |
2. P | C5JJ91 | Tethering factor for nuclear proteasome STS1 | 9.30e-02 | 1.42e-02 | NA |
2. P | Q96F83 | Uncharacterized protein CLBA1 | 5.33e-01 | 1.04e-02 | NA |
2. P | C5P8M7 | Tethering factor for nuclear proteasome STS1 | 1.29e-01 | 1.38e-02 | NA |
2. P | C1GLQ3 | Tethering factor for nuclear proteasome STS1 | 8.54e-02 | 9.07e-03 | NA |
2. P | C4YCB9 | Tethering factor for nuclear proteasome STS1 | 1.15e-01 | 2.87e-03 | NA |
2. P | E9D0S5 | Tethering factor for nuclear proteasome STS1 | 7.45e-02 | 1.38e-02 | NA |
2. P | O44740 | Meiotic spindle formation protein 2 | 8.54e-02 | 3.20e-03 | NA |
2. P | P0CZ24 | Putative acyl-coenzyme A oxidase At3g06690 | 7.03e-02 | 2.96e-03 | NA |
2. P | A0A182BSR9 | Secreted RxLR effector protein 16 | 8.20e-02 | 1.86e-02 | NA |
3. B | P0CF75 | Endogenous Bornavirus-like nucleoprotein 1 | 1.76e-12 | NA | 1.69e-108 |
3. B | P0C797 | Nucleoprotein | NA | NA | 2.90e-45 |
3. B | P0C796 | Nucleoprotein | NA | NA | 2.55e-45 |