Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 2. P was
P0DMW3
(Small integral membrane protein 10-like protein 1) with a FATCAT P-Value: 0.00413 and RMSD of 1.99 angstrom. The sequence alignment identity is 15.7%.
Structural alignment shown in left. Query protein Q6W349 colored as red in alignment, homolog P0DMW3 colored as blue.
Query protein Q6W349 is also shown in right top, homolog P0DMW3 showed in right bottom. They are colored based on secondary structures.
Q6W349 MPTSETSWWPGACLCSSCAWTSDSRFFNLWTLGLAPAASQGFSGLKPQTDDCT-VSFPGFEAFGLG---LSHY---WHL--SFPACRQSIMGLCLVIVLA 91 P0DMW3 ---------------------------------MAPAAAPSSLAVRASSPAATPTSY-GVFCKGLSRTLLAFFELAWQLRMNFP--YFYVAG---SVIL- 60 Q6W349 NSS----- 94 P0DMW3 NIRLQVHI 68
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source | GO | Description |
---|---|---|
2. P | GO:0035023 | regulation of Rho protein signal transduction |
2. P | GO:0045664 | regulation of neuron differentiation |
2. P | GO:0009966 | regulation of signal transduction |
2. P | GO:0005634 | nucleus |
2. P | GO:0031103 | axon regeneration |
2. P | GO:0005938 | cell cortex |
2. P | GO:0031267 | small GTPase binding |
2. P | GO:0017015 | regulation of transforming growth factor beta receptor signaling pathway |
2. P | GO:0005856 | cytoskeleton |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
---|---|---|---|---|---|
1. PB | Q6W349 | Putative uncharacterized protein encoded by LINC00575 | 0 | 2.25e-141 | 3.61e-64 |
2. P | P47066 | Putative uncharacterized protein YJL009W | 1.65e-01 | 5.52e-03 | NA |
2. P | P68620 | Protein A54 | NA | 5.50e-04 | NA |
2. P | Q8WZB0 | Putative uncharacterized protein encoded by LINC00476 | 7.04e-01 | 1.98e-02 | NA |
2. P | P10435 | Uncharacterized immunity region protein 12 | NA | 1.43e-03 | NA |
2. P | P92548 | Uncharacterized mitochondrial protein AtMg01180 | 3.97e-01 | 2.15e-02 | NA |
2. P | Q96M85 | Putative uncharacterized protein FLJ32756 | 3.37e-01 | 4.82e-02 | NA |
2. P | Q9VNE7 | CDC42 small effector protein homolog | 2.06e-01 | 1.89e-02 | NA |
2. P | P34238 | Putative uncharacterized protein YKL177W | 8.13e-03 | 3.28e-03 | NA |
2. P | P25640 | Putative uncharacterized protein YCR064C | 2.64e-01 | 3.07e-03 | NA |
2. P | Q9ULZ0 | TP53-target gene 3 protein | 7.27e-01 | 1.55e-04 | NA |
2. P | P68621 | Protein A54 | NA | 5.50e-04 | NA |
2. P | Q04923 | Putative uncharacterized protein YDR220C | 7.94e-01 | 9.73e-03 | NA |
2. P | Q90667 | Neuronal regeneration-related protein | 7.30e-01 | 2.84e-02 | NA |
2. P | P0DMW3 | Small integral membrane protein 10-like protein 1 | 4.13e-03 | 2.28e-07 | NA |
2. P | P61580 | Endogenous retrovirus group K member 10 Np9 protein | 5.43e-01 | 3.30e-02 | NA |