Summary

Q6ZRG5

Homolog: P10164.
Function: Acidic proline-rich protein PRP25 (Fragment).

Statistics

Total GO Annotation: 58
Unique PROST Go: 55
Unique BLAST Go: 3

Total Homologs: 90
Unique PROST Homologs: 84
Unique BLAST Homologs: 5

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was P10164 (Acidic proline-rich protein PRP25 (Fragment)) with a FATCAT P-Value: 0.0108 and RMSD of 4.99 angstrom. The sequence alignment identity is 22.4%.
Structural alignment shown in left. Query protein Q6ZRG5 colored as red in alignment, homolog P10164 colored as blue. Query protein Q6ZRG5 is also shown in right top, homolog P10164 showed in right bottom. They are colored based on secondary structures. 

  Q6ZRG5 MMRWNFSPEDLSSIFRNNSTLPKITVKNVDIEFT--IPTAVTIEVEP-SPVQ-QDNPPISSEQADFSLAQPDSPSLPLESPEESESSAQQEATAQTPNPP 96
  P10164 ---------------------------MLVVLFTAVLLT-LSYAQEPGDELQILDQTP---NQ------KPPPPGFP---PRPPANGSQQ-------GPP 53

  Q6ZRG5 KEVEP--SPVQQEFPAEPTEPAKEVEPSATQQEASGHPLKSTKEVNPPP---KQEIPAQPSEP--------PEKVELSPVLQQAPTQLLEPLKKVECSPV 183
  P10164 PQGGPQQSPLQ---PGKPQDP----PPQGSPQQ---KPPQPGKPQGPPPPGGPQKKPPQPGKPQGPPPPGGPQKKPPQPGKPQGPTPPGGPQQK----PP 139

  Q6ZRG5 QQAVPAQSSEP---SIVVEPSPVQQIAHLCLQSSLRKWNPL 221
  P10164 QAGKP-QGPPPPGGPQQKPPQPGNQ------QGPPPPGGP- 172

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0005509 calcium ion binding
2. P GO:0045735 nutrient reservoir activity
2. P GO:0035686 sperm fibrous sheath
2. P GO:0018149 peptide cross-linking
2. P GO:0050901 leukocyte tethering or rolling
2. P GO:0044853 plasma membrane raft
2. P GO:0008191 metalloendopeptidase inhibitor activity
2. P GO:0001515 opioid peptide activity
2. P GO:0005199 structural constituent of cell wall
2. P GO:0046848 hydroxyapatite binding
2. P GO:0030154 cell differentiation
2. P GO:0030216 keratinocyte differentiation
2. P GO:0030430 host cell cytoplasm
2. P GO:0017069 snRNA binding
2. P GO:0043159 acrosomal matrix
2. P GO:0005200 structural constituent of cytoskeleton
2. P GO:0045095 keratin filament
2. P GO:0033234 negative regulation of protein sumoylation
2. P GO:0030097 hemopoiesis
2. P GO:0005201 extracellular matrix structural constituent
2. P GO:0043036 starch grain
2. P GO:0005689 U12-type spliceosomal complex
2. P GO:0007283 spermatogenesis
2. P GO:0031424 keratinization
2. P GO:0009664 plant-type cell wall organization
2. P GO:0045987 positive regulation of smooth muscle contraction
2. P GO:0052576 carbohydrate storage
2. P GO:2001070 starch binding
2. P GO:0031514 motile cilium
2. P GO:0030317 flagellated sperm motility
2. P GO:0007218 neuropeptide signaling pathway
2. P GO:0039503 suppression by virus of host innate immune response
2. P GO:0007288 sperm axoneme assembly
2. P GO:0034237 protein kinase A regulatory subunit binding
2. P GO:0097228 sperm principal piece
2. P GO:0005829 cytosol
2. P GO:0033150 cytoskeletal calyx
2. P GO:0005576 extracellular region
2. P GO:0009530 primary cell wall
2. P GO:0010224 response to UV-B
2. P GO:0005882 intermediate filament
2. P GO:0050902 leukocyte adhesive activation
2. P GO:0001931 uropod
2. P GO:0071933 Arp2/3 complex binding
2. P GO:0005856 cytoskeleton
2. P GO:0043662 peribacteroid fluid
2. P GO:0006952 defense response
2. P GO:0042311 vasodilation
2. P GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation
2. P GO:0050900 leukocyte migration
2. P GO:0005938 cell cortex
2. P GO:0031214 biomineral tissue development
2. P GO:0009877 nodulation
2. P GO:0003785 actin monomer binding
2. P GO:0001533 cornified envelope
3. B GO:0004222 metalloendopeptidase activity
3. B GO:0016021 integral component of membrane
3. B GO:0005618 cell wall

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q6ZRG5 Putative uncharacterized protein FLJ43944 0 3.24e-162 5.66e-150
2. P J9VL95 Copper metallothionein 2 9.85e-01 1.62e-03 NA
2. P P87269 Putative uncharacterized protein YDR433W 7.84e-01 1.13e-02 NA
2. P Q9Y0X6 BmK-YA precursor 9.11e-01 8.96e-03 NA
2. P Q08696 Axoneme-associated protein mst101(2) 9.86e-01 2.52e-03 NA
2. P Q4ZJZ1 Protease inhibitor Egf1.5b NA 1.45e-03 NA
2. P H0YM25 Golgin subfamily A member 6-like protein 22 9.87e-01 2.11e-03 NA
2. P Q09550 Uncharacterized protein F26C11.3 8.80e-01 4.69e-05 NA
2. P Q62170 P-selectin glycoprotein ligand 1 3.18e-01 5.40e-03 NA
2. P P08416 Zein-alpha GZ19AB11 5.36e-01 2.14e-02 NA
2. P P24450 Zein-alpha PMS2 6.80e-01 1.09e-02 NA
2. P P21850 [D-Ala2]-deltorphins 4.25e-02 1.15e-05 NA
2. P P08462 Submandibular gland secretory Glx-rich protein CB 5.53e-02 1.01e-03 NA
2. P P10165 Proline-rich proteoglycan 2 1.36e-01 4.31e-03 NA
2. P P35663 Cylicin-1 4.70e-01 2.50e-04 NA
2. P P08489 Glutenin, high molecular weight subunit PW212 7.03e-01 9.33e-04 NA
2. P Q90WZ1 Kininogen-1b 9.35e-01 6.47e-03 NA
2. P P60369 Keratin-associated protein 10-3 5.35e-01 3.03e-03 NA
2. P Q5XPK0 Scar-like domain-containing protein WAVE 5 9.51e-01 4.60e-02 NA
2. P P56164 Major pollen allergen Pha a 5.1 8.48e-01 2.18e-06 NA
2. P Q9SJM4 GLABROUS1 enhancer-binding protein-like 3 3.76e-01 7.34e-03 NA
2. P A0A0J9YWL9 Putative testis-expressed protein 13C 7.45e-01 2.28e-04 NA
2. P Q2T9N0 Fibrous sheath CABYR-binding protein 7.29e-01 2.29e-02 NA
2. P Q6R648 Keratin-associated protein 11-1 6.36e-01 2.70e-02 NA
2. P Q4ZJZ3 Protease inhibitor Egf1.5a NA 1.94e-03 NA
2. P Q8N7X1 RNA-binding motif protein, X-linked-like-3 7.03e-01 5.75e-03 NA
2. P P08568 Submandibular gland secretory Glx-rich protein CA 3.30e-02 2.74e-03 NA
2. P Q02752 Acidic phosphoprotein 3.23e-01 1.19e-02 NA
2. P Q7T1M3 Bradykinin-potentiating and C-type natriuretic peptides isoform 2 (Fragment) 2.89e-01 1.48e-04 NA
2. P P0DJ89 Secreted effector protein EspF(U) 2.66e-01 1.85e-04 NA
2. P P06676 Zein-alpha 19C1 7.29e-01 2.73e-02 NA
2. P P21733 Uncharacterized 29.1 kDa protein in cryB1 5'region 9.89e-01 1.39e-03 NA
2. P Q8NC38 Putative uncharacterized protein ZNF436-AS1 3.51e-02 3.61e-04 NA
2. P Q9UHL3 Protein FAM153A 3.71e-01 2.07e-03 NA
2. P P14606 Cyclic AMP-inducible protein BP74 9.79e-01 9.03e-05 NA
2. P P06679 22 kDa alpha-zein 8b (Fragment) 8.19e-01 3.30e-02 NA
2. P P60014 Keratin-associated protein 10-10 3.36e-01 1.52e-02 NA
2. P A1EGX6 Fibrous sheath CABYR-binding protein 8.02e-01 2.05e-02 NA
2. P P24709 Involucrin 1.73e-01 4.37e-02 NA
2. P Q08DY0 Glutamate-rich protein 5 1.70e-01 5.40e-03 NA
2. P Q28092 Cylicin-2 4.30e-01 3.74e-04 NA
2. P Q6GZS6 Uncharacterized protein 050L NA 1.00e-05 NA
2. P Q8N660 Neuroblastoma breakpoint family member 15 1.28e-01 6.55e-05 NA
2. P Q01030 Uncharacterized gene 45 protein NA 3.41e-03 NA
2. P P04699 22 kDa alpha-zein 8 6.45e-01 4.64e-02 NA
2. P Q0II65 Coiled-coil domain-containing protein 70 4.56e-01 3.02e-02 NA
2. P P10388 Glutenin, high molecular weight subunit DX5 5.63e-01 4.46e-03 NA
2. P P06674 Zein-alpha 19A2 (Fragment) 6.47e-01 2.05e-02 NA
2. P P0DJ88 Secreted effector protein EspF(U) 3.55e-01 1.85e-04 NA
2. P P10322 Nodulin-25 1.52e-01 4.39e-06 NA
2. P O17389 Thymosin beta 4.99e-01 1.95e-02 NA
2. P P24449 Zein-alpha PMS1 6.70e-01 4.80e-04 NA
2. P P04474 Acidic proline-rich protein PRP33 1.11e-02 6.33e-09 NA
2. P Q6IC83 Uncharacterized protein C22orf42 1.22e-01 6.30e-04 NA
2. P Q68FX6 Calcium-binding and spermatid-specific protein 1 1.81e-01 1.65e-02 NA
2. P A0A0J9YY54 Testis-expressed protein 13D 4.37e-01 8.50e-03 NA
2. P F8W0I5 Nuclear pore complex-interacting protein family member B12 7.63e-01 4.46e-03 NA
2. P Q5TI25 Neuroblastoma breakpoint family member 14 4.07e-01 7.21e-05 NA
2. P P06678 Zein-alpha 19D1 7.19e-01 1.72e-02 NA
2. P P35662 Cylicin-1 5.61e-01 3.47e-02 NA
2. P Q8X482 Secreted effector protein EspF(U) NA 2.25e-04 NA
2. P Q14093 Cylicin-2 1.85e-01 7.05e-04 NA
2. P P04702 Zein-alpha M6 4.53e-01 1.44e-03 NA
2. P P60410 Keratin-associated protein 10-8 3.22e-01 3.33e-03 NA
2. P P10164 Acidic proline-rich protein PRP25 (Fragment) 1.08e-02 6.89e-03 NA
2. P P06675 Zein-alpha 19B1 7.71e-01 4.42e-02 NA
2. P P21138 Serine-rich 25 kDa antigen protein 3.87e-02 8.53e-04 NA
2. P P02859 Zein-alpha A30 7.73e-01 2.28e-03 NA
2. P Q28658 Small proline-rich protein 3 7.05e-01 2.41e-03 NA
2. P Q49537 Variant surface antigen E 2.54e-01 5.69e-03 NA
2. P Q25434 Adhesive plaque matrix protein 5.23e-01 1.75e-06 NA
2. P P60368 Keratin-associated protein 10-2 4.93e-01 3.88e-02 NA
2. P Q8IUC1 Keratin-associated protein 11-1 3.89e-01 1.77e-05 NA
2. P K7TUP3 22 kDa alpha-zein 8 6.26e-01 2.05e-02 NA
2. P P04705 Zein-alpha PZ19.1 (Fragment) 5.92e-01 2.96e-02 NA
2. P Q41896 Protein FLOURY 2 1.91e-01 1.54e-02 NA
2. P P60413 Keratin-associated protein 10-12 4.11e-01 9.65e-04 NA
2. P P05422 Dermorphin-1 5.07e-02 1.68e-03 NA
2. P Q09239 Uncharacterized protein C28F5.1 2.00e-01 1.77e-03 NA
2. P Q6PEX3 Keratin-associated protein 26-1 4.89e-02 2.39e-04 NA
2. P C6UYI3 Secreted effector protein EspF(U) 2.59e-01 1.85e-04 NA
2. P E2RYF7 Protein PBMUCL2 6.97e-01 1.21e-04 NA
2. P P06599 Extensin 2.96e-02 1.02e-02 NA
2. P Q5UPC9 Uncharacterized protein L53 NA 3.11e-02 NA
2. P A0A1B0GUY1 MARCO-like protein 9.73e-02 6.96e-05 NA
3. B Q8DQN5 Zinc metalloprotease ZmpB 9.81e-01 NA 1.93e-04
3. B A6NM11 Leucine-rich repeat-containing protein 37A2 9.42e-01 NA 1.38e-06
3. B A6NMS7 Leucine-rich repeat-containing protein 37A 9.00e-01 NA 1.33e-06
3. B Q96QE4 Leucine-rich repeat-containing protein 37B 5.83e-01 NA 0.017
3. B O60309 Leucine-rich repeat-containing protein 37A3 8.73e-01 NA 8.63e-04