Summary

Q75MW2

Homolog: Q5M853.
Function: KxDL motif-containing protein 1.

Statistics

Total GO Annotation: 120
Unique PROST Go: 104
Unique BLAST Go: 15

Total Homologs: 105
Unique PROST Homologs: 96
Unique BLAST Homologs: 7

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was Q5M853 (KxDL motif-containing protein 1) with a FATCAT P-Value: 2.88e-07 and RMSD of 3.26 angstrom. The sequence alignment identity is 19.2%.
Structural alignment shown in left. Query protein Q75MW2 colored as red in alignment, homolog Q5M853 colored as blue. Query protein Q75MW2 is also shown in right top, homolog Q5M853 showed in right bottom. They are colored based on secondary structures. 

  Q75MW2 MEEAAAAPISPWTMAATIQAMERKIESQAAHL-----LSLEGQTG------MAEKKLAD-CEKT---AVEFGNQLEGKWAV-L-----------GTLL-- 71
  Q5M853 --------------------MDTP-DS-ASRVFCGRFLSMV-NTDDVNAIILAQKNMLDRFEKTNEMLLNF-NNLS---SVRLQQMSERFMHHTRTLVDM 73

  Q75MW2 -QEYGLLQRRLENVENLL---HNRNFWILRLPPGS----KGESP-----KTTPSPSPRSSPRLNKGR---SPATGAALTPRFQMFLWTP--VQMQKLRPS 153
  Q5M853 KRDLDSIFRRIRTLKGKLARQHPEAF--SHIPEGSLLEDEDEDPVPPSITTTIATSEQST-----GSCDTSPDTA---SPSF-----SPGFEDLSHIRPG 158

  Q75MW2 RD----------------- 155
  Q5M853 SPAINGHSQTDDEEETREE 177

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
1. PB GO:0005634 nucleus
2. P GO:0045666 positive regulation of neuron differentiation
2. P GO:0043968 histone H2A acetylation
2. P GO:0051010 microtubule plus-end binding
2. P GO:0034993 meiotic nuclear membrane microtubule tethering complex
2. P GO:0008057 eye pigment granule organization
2. P GO:0008608 attachment of spindle microtubules to kinetochore
2. P GO:0045141 meiotic telomere clustering
2. P GO:0051028 mRNA transport
2. P GO:0007080 mitotic metaphase plate congression
2. P GO:0032922 circadian regulation of gene expression
2. P GO:0031083 BLOC-1 complex
2. P GO:0099078 BORC complex
2. P GO:0005874 microtubule
2. P GO:0007100 mitotic centrosome separation
2. P GO:0051898 negative regulation of protein kinase B signaling
2. P GO:0005080 protein kinase C binding
2. P GO:0047496 vesicle transport along microtubule
2. P GO:0009904 chloroplast accumulation movement
2. P GO:0007399 nervous system development
2. P GO:0048511 rhythmic process
2. P GO:0007249 I-kappaB kinase/NF-kappaB signaling
2. P GO:0000187 obsolete activation of MAPK activity
2. P GO:1990467 NuA3a histone acetyltransferase complex
2. P GO:0035267 NuA4 histone acetyltransferase complex
2. P GO:0016573 histone acetylation
2. P GO:0070776 MOZ/MORF histone acetyltransferase complex
2. P GO:0072686 mitotic spindle
2. P GO:0021522 spinal cord motor neuron differentiation
2. P GO:0010520 regulation of reciprocal meiotic recombination
2. P GO:0003714 transcription corepressor activity
2. P GO:0048665 neuron fate specification
2. P GO:0016192 vesicle-mediated transport
2. P GO:0140444 cytoskeleton-nuclear membrane anchor activity
2. P GO:0009903 chloroplast avoidance movement
2. P GO:0070374 positive regulation of ERK1 and ERK2 cascade
2. P GO:0043189 H4/H2A histone acetyltransferase complex
2. P GO:0000212 meiotic spindle organization
2. P GO:1901003 negative regulation of fermentation
2. P GO:0030473 nuclear migration along microtubule
2. P GO:0007020 microtubule nucleation
2. P GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore
2. P GO:0007049 cell cycle
2. P GO:0005789 endoplasmic reticulum membrane
2. P GO:0051311 meiotic metaphase plate congression
2. P GO:0007405 neuroblast proliferation
2. P GO:0042110 T cell activation
2. P GO:0005901 caveola
2. P GO:0005765 lysosomal membrane
2. P GO:0007059 chromosome segregation
2. P GO:0007019 microtubule depolymerization
2. P GO:0046966 thyroid hormone receptor binding
2. P GO:0045132 meiotic chromosome segregation
2. P GO:0051303 establishment of chromosome localization
2. P GO:0005815 microtubule organizing center
2. P GO:1990468 NuA3b histone acetyltransferase complex
2. P GO:0036410 Mst2 histone acetyltransferase complex
2. P GO:0051301 cell division
2. P GO:0043983 histone H4-K12 acetylation
2. P GO:0051642 centrosome localization
2. P GO:0043981 histone H4-K5 acetylation
2. P GO:0097028 dendritic cell differentiation
2. P GO:0031616 spindle pole centrosome
2. P GO:0051315 attachment of mitotic spindle microtubules to kinetochore
2. P GO:0005814 centriole
2. P GO:0042599 lamellar body
2. P GO:0030308 negative regulation of cell growth
2. P GO:0051455 monopolar spindle attachment to meiosis I kinetochore
2. P GO:0031023 microtubule organizing center organization
2. P GO:0044154 histone H3-K14 acetylation
2. P GO:0009648 photoperiodism
2. P GO:0005640 nuclear outer membrane
2. P GO:2000574 obsolete regulation of microtubule motor activity
2. P GO:1990758 mitotic sister chromatid biorientation
2. P GO:0010090 trichome morphogenesis
2. P GO:0070682 proteasome regulatory particle assembly
2. P GO:0070097 delta-catenin binding
2. P GO:1990537 mitotic spindle polar microtubule
2. P GO:0009649 entrainment of circadian clock
2. P GO:0000278 mitotic cell cycle
2. P GO:0055028 cortical microtubule
2. P GO:0048309 endoplasmic reticulum inheritance
2. P GO:0044565 dendritic cell proliferation
2. P GO:0042729 DASH complex
2. P GO:0030866 cortical actin cytoskeleton organization
2. P GO:0032418 lysosome localization
2. P GO:0031262 Ndc80 complex
2. P GO:0005813 centrosome
2. P GO:0032991 protein-containing complex
2. P GO:0043982 histone H4-K8 acetylation
2. P GO:0015630 microtubule cytoskeleton
2. P GO:0043972 histone H3-K23 acetylation
2. P GO:0045098 type III intermediate filament
2. P GO:0045599 negative regulation of fat cell differentiation
2. P GO:0007528 neuromuscular junction development
2. P GO:0051298 centrosome duplication
2. P GO:0005856 cytoskeleton
2. P GO:1904750 negative regulation of protein localization to nucleolus
2. P GO:0045334 clathrin-coated endocytic vesicle
2. P GO:0005912 adherens junction
2. P GO:0000776 kinetochore
2. P GO:0045211 postsynaptic membrane
2. P GO:1990942 mitotic metaphase chromosome recapture
2. P GO:0042753 positive regulation of circadian rhythm
2. P GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter
3. B GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
3. B GO:0003700 DNA-binding transcription factor activity
3. B GO:0000976 transcription cis-regulatory region binding
3. B GO:1901216 positive regulation of neuron death
3. B GO:0000122 negative regulation of transcription by RNA polymerase II
3. B GO:0006357 regulation of transcription by RNA polymerase II
3. B GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
3. B GO:0045892 negative regulation of transcription, DNA-templated
3. B GO:0006355 regulation of transcription, DNA-templated
3. B GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
3. B GO:0031625 ubiquitin protein ligase binding
3. B GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
3. B GO:0045944 positive regulation of transcription by RNA polymerase II
3. B GO:0042802 identical protein binding
3. B GO:0005654 nucleoplasm

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q6ZMS7 Protein ZNF783 1.71e-04 8.58e-04 1.62e-53
1. PB Q75MW2 Protein ZNF767 0 1.64e-150 1.66e-111
2. P Q6QZQ4 Vimentin-type intermediate filament-associated coiled-coil protein 1.61e-05 5.63e-06 NA
2. P Q29RU3 Coiled-coil domain-containing protein 54 1.75e-04 1.51e-04 NA
2. P A4FV37 Caveolae-associated protein 3 2.12e-05 3.37e-02 NA
2. P Q06568 Nuclear distribution protein nudE homolog 1 1.23e-05 4.97e-11 NA
2. P F4I0N3 WEB family protein At1g75720 6.03e-04 6.46e-04 NA
2. P Q9VTC2 Biogenesis of lysosome-related organelles complex 1 subunit 4 9.22e-06 9.02e-04 NA
2. P O83819 Uncharacterized protein TP_0847 NA 2.63e-03 NA
2. P O48822 WEB family protein At2g17940 1.14e-04 4.04e-04 NA
2. P B8AN27 Guanine nucleotide-binding protein subunit gamma 1 3.03e-03 1.05e-03 NA
2. P C7GY13 SWI5-dependent HO expression protein 3 5.43e-04 3.96e-02 NA
2. P Q9BW66 Cyclin-dependent kinase 2-interacting protein 1.56e-04 1.03e-04 NA
2. P Q75ED7 DASH complex subunit DUO1 3.05e-06 1.53e-03 NA
2. P Q6FJ46 Chromatin modification-related protein EAF6 6.69e-03 7.21e-06 NA
2. P Q80HV0 17 kDa A-type inclusion protein NA 8.10e-03 NA
2. P Q08955 Chromosome segregation in meiosis protein 4 1.91e-06 2.76e-05 NA
2. P Q32P96 Spermatogenesis-associated protein 45 1.10e-01 9.66e-05 NA
2. P Q91VJ2 Caveolae-associated protein 3 4.65e-04 6.17e-05 NA
2. P Q5JMF2 Probable protein ABIL5 4.02e-04 3.55e-05 NA
2. P C5DLA5 SWI5-dependent HO expression protein 3 6.55e-04 6.14e-04 NA
2. P Q2TA00 Coiled-coil domain-containing protein 83 4.37e-03 3.15e-05 NA
2. P A6H7E2 Cyclin-dependent kinase 2-interacting protein 7.65e-04 4.57e-02 NA
2. P Q5NB83 Probable protein ABIL3 4.82e-04 6.80e-04 NA
2. P Q8NEL0 Coiled-coil domain-containing protein 54 1.58e-04 7.13e-06 NA
2. P Q8IR45 BLOC-1-related complex subunit 8 homolog 2.25e-05 2.94e-06 NA
2. P Q8BGD0 Uncharacterized protein C3orf14 homolog 1.20e-06 6.76e-03 NA
2. P Q6R7B4 Uncharacterized protein ORF3 NA 1.86e-02 NA
2. P Q5T686 Arginine vasopressin-induced protein 1 8.00e-02 1.18e-02 NA
2. P B3LW62 Kinetochore protein Spc25 9.70e-04 5.44e-06 NA
2. P Q7T3I0 Zinc finger C4H2 domain-containing protein 5.00e-04 1.73e-02 NA
2. P Q6NMC6 Protein ABIL3 8.63e-04 3.72e-02 NA
2. P Q9AXA6 Probable protein ABIL1 4.12e-04 1.84e-05 NA
2. P Q5M853 KxDL motif-containing protein 1 2.88e-07 4.80e-07 NA
2. P Q8TDR4 T-complex protein 10A homolog 1 4.53e-04 3.82e-08 NA
2. P A2CEM9 Coiled-coil domain-containing protein 85B 3.80e-05 2.51e-04 NA
2. P P50084 Protein BNS1 1.98e-03 3.28e-02 NA
2. P Q0VC19 Coiled-coil domain-containing protein 184 9.08e-06 3.75e-05 NA
2. P Q5T0J7 Testis-expressed protein 35 2.32e-05 1.82e-05 NA
2. P Q8S8F5 Protein ELF4-LIKE 3 9.82e-05 3.23e-03 NA
2. P Q6DBR9 KxDL motif-containing protein 1 1.52e-06 1.77e-06 NA
2. P Q6PDY0 Coiled-coil domain-containing protein 85B 4.15e-05 1.67e-03 NA
2. P Q0V9C8 KxDL motif-containing protein 1 6.71e-06 7.80e-07 NA
2. P P0C7N2 Glutamate-rich protein 4 4.18e-04 1.07e-02 NA
2. P Q6I588 Probable protein ABIL4 4.52e-04 5.90e-04 NA
2. P Q8S8M5 Protein ABIL1 1.85e-04 4.29e-02 NA
2. P A7YWC8 Vimentin-type intermediate filament-associated coiled-coil protein 5.13e-05 1.93e-02 NA
2. P Q95K40 Coiled-coil domain-containing protein 83 2.50e-03 7.32e-05 NA
2. P Q4V8F1 Coiled-coil domain-containing protein 184 1.11e-05 6.65e-05 NA
2. P Q6CUD4 DASH complex subunit DUO1 7.88e-04 2.13e-02 NA
2. P Q9HDZ6 DASH complex subunit dam1 1.63e-04 4.86e-07 NA
2. P Q3SZR0 Arginine vasopressin-induced protein 1 5.17e-01 9.96e-03 NA
2. P Q6GM07 Cyclin-dependent kinase 2-interacting protein 9.65e-04 4.34e-04 NA
2. P P0C7M3 Surfactant-associated protein 3 2.24e-02 5.70e-03 NA
2. P Q9QYP6 5-azacytidine-induced protein 2 2.09e-03 8.90e-03 NA
2. P Q3SYW5 5-azacytidine-induced protein 2 2.29e-03 1.65e-02 NA
2. P Q6CQV5 Biogenesis of lysosome-related organelles complex 1 subunit VAB2 1.28e-05 1.26e-02 NA
2. P Q75AC2 Biogenesis of lysosome-related organelles complex 1 subunit VAB2 2.02e-04 2.40e-02 NA
2. P Q3KPT0 Coiled-coil domain-containing protein 169 9.61e-05 1.97e-05 NA
2. P Q12513 Translation machinery-associated protein 17 5.96e-05 1.32e-03 NA
2. P A6ZL74 SWI5-dependent HO expression protein 3 2.75e-03 3.96e-02 NA
2. P Q969G5 Caveolae-associated protein 3 2.97e-05 7.08e-04 NA
2. P Q9BQD3 KxDL motif-containing protein 1 2.85e-06 1.37e-06 NA
2. P Q64EW0 Kinetochore protein Spc25 4.18e-05 5.33e-03 NA
2. P Q6FTI5 DASH complex subunit DAD2 3.72e-06 5.38e-04 NA
2. P Q52MB2 Coiled-coil domain-containing protein 184 2.66e-05 4.56e-05 NA
2. P Q4KMA0 5-azacytidine-induced protein 2 6.41e-03 4.84e-03 NA
2. P Q8BP01 Vimentin-type intermediate filament-associated coiled-coil protein 2.23e-05 1.37e-06 NA
2. P F4IMQ0 Protein FLC EXPRESSOR 2.12e-03 6.33e-03 NA
2. P Q9SD24 WEB family protein At3g51220 9.98e-04 7.64e-05 NA
2. P Q8IWF9 Coiled-coil domain-containing protein 83 9.61e-05 1.93e-02 NA
2. P Q75WU1 Guanine nucleotide-binding protein subunit gamma 1 2.25e-03 1.05e-03 NA
2. P Q9FHY1 Protein ABIL4 3.54e-04 4.81e-05 NA
2. P Q3SZV2 KxDL motif-containing protein 1 4.70e-06 9.13e-06 NA
2. P Q8NBT2 Kinetochore protein Spc24 2.58e-04 1.53e-02 NA
2. P Q14BK3 Testis-expressed protein 35 1.21e-04 1.65e-05 NA
2. P O14240 Chromatin modification-related protein eaf6 6.75e-04 1.19e-02 NA
2. P Q64EV9 Kinetochore protein Spc25 6.65e-05 1.83e-02 NA
2. P Q5R8D4 Arginine vasopressin-induced protein 1 7.62e-02 2.53e-03 NA
2. P Q68US1 T-complex protein 10A homolog 1 2.60e-04 8.27e-07 NA
2. P A7TJJ7 SWI5-dependent HO expression protein 3 2.51e-02 4.80e-03 NA
2. P Q15834 Coiled-coil domain-containing protein 85B 2.41e-06 8.73e-03 NA
2. P Q570U6 Protein ELF4-LIKE 4 6.19e-06 1.84e-04 NA
2. P Q9CZA6 Nuclear distribution protein nudE homolog 1 3.74e-04 2.81e-02 NA
2. P Q6DDT0 KxDL motif-containing protein 1 1.12e-05 1.71e-08 NA
2. P Q2YDE5 Putative coiled-coil domain-containing protein 196 2.52e-04 1.07e-06 NA
2. P Q94BS8 Protein ELF4-LIKE 2 1.93e-05 1.81e-02 NA
2. P Q2YDF2 Mediator of RNA polymerase II transcription subunit 30 1.27e-03 5.41e-08 NA
2. P Q2NL98 Vimentin-type intermediate filament-associated coiled-coil protein 4.40e-05 4.53e-02 NA
2. P Q9Z1H9 Caveolae-associated protein 3 2.61e-04 4.53e-03 NA
2. P A1L168 Uncharacterized protein C20orf202 8.38e-03 4.66e-03 NA
2. P Q9H6S1 5-azacytidine-induced protein 2 3.18e-03 4.74e-02 NA
2. P Q9DAL3 Coiled-coil domain-containing protein 54 2.71e-04 1.76e-02 NA
2. P Q80XH1 KxDL motif-containing protein 1 1.40e-06 9.43e-09 NA
2. P Q9NQZ6 Zinc finger C4H2 domain-containing protein 2.28e-04 1.16e-02 NA
2. P Q8BMK5 Coiled-coil domain-containing protein 184 3.84e-05 5.03e-05 NA
2. P Q68FG0 Zinc finger C4H2 domain-containing protein 6.83e-06 1.16e-02 NA
2. P Q9D083 Kinetochore protein Spc24 9.91e-06 1.12e-03 NA
3. B Q3B7M4 Zinc finger protein 746 3.74e-03 NA 1.24e-63
3. B Q8TD17 Zinc finger protein 398 2.13e-02 NA 5.71e-46
3. B Q6NUN9 Zinc finger protein 746 2.91e-03 NA 3.29e-63
3. B Q9UDV6 Zinc finger protein 212 1.09e-03 NA 1.91e-53
3. B Q9UDV7 Zinc finger protein 282 1.32e-04 NA 5.42e-50
3. B Q9ULD5 Zinc finger protein 777 2.36e-02 NA 7.84e-44
3. B Q3U133 Zinc finger protein 746 3.57e-03 NA 3.60e-62