Summary

Q7L0X2

Homolog: Q5XI56.
Function: Glutamate-rich protein 6.

Statistics

Total GO Annotation: 19
Unique PROST Go: 18
Unique BLAST Go: 1

Total Homologs: 9
Unique PROST Homologs: 3
Unique BLAST Homologs: 2

Structures and Sequence Alignment

The best structural homolog that predicted by 1. PB was Q5XI56 (Glutamate-rich protein 6) with a FATCAT P-Value: 2.97e-08 and RMSD of 5.34 angstrom. The sequence alignment identity is 56.2%.
Structural alignment shown in left. Query protein Q7L0X2 colored as red in alignment, homolog Q5XI56 colored as blue. Query protein Q7L0X2 is also shown in right top, homolog Q5XI56 showed in right bottom. They are colored based on secondary structures. 

  Q7L0X2 MAHLRSPSGFGDPGKKDQKESEEELEEEEEEEEVEEEEEEVEEEEEEVEEEEEEVVEEELVGEEQELEAPETFSEEYLWKVTDI-GDYDDDFPDVRPRLA 99
  Q5XI56 -------------------------------------------------------------------------MEDDIWKAVDLSGVFDEDSVELRPRLT 27

  Q7L0X2 SIVSPSLTSTFVPSQ-SATS-TE----TP--SASPPSSTSSHKSFPKIFQTFRKDMSEMSIDRNIHRNLSPGIPVSVQTEE-SWLQDLSDKVQSRKKASK 190
  Q5XI56 SVSSPSLSSTPPPSPLSSPSWSEEELPAPRSDGSPASSISAHKSYPKIFQTFKKDLSEVTVDRLMYPSFYERVQISIQTEDQSWLQ----RISARKRIKR 123

  Q7L0X2 ----EKAE-P-ECLASKLREKWVINPEESKLNILYELEFKEDFITLFEPSLRTLPSIGPPSILAYKEESSNLGINFKDEEE--ETSPKCEFCGSDLRAFF 282
  Q5XI56 IPSIEITEAPQENLASKLRENWVINPEEPKLSILCEMEFNEDFVNFFETSLRTLPSIGPPTILSYRKEYSCMDVILKDEQELGAT---CEFCGSDLQSLF 220

  Q7L0X2 SNVDVSSE---PKG--HASCCIAFQNLIDYIYEEQIKTKPPKAELIAIDPHAAHGSEVDRLKAKEKALQRKQEQRMARHFAIISREQTHF-SEDDSKRLK 376
  Q5XI56 FNMDTSLDDAGTKGKSHRSCCLQFQNLLDYITEERLTTKSPEMELISISPHAAHGSDADRLKAKEKAMQRKQERQMARHFTIIP-EQSPVGTEEDTKHLK 319

  Q7L0X2 TISYQLSVD-IPEKQI-IDDIVFDFQLRNSNMSIICCDS-RIACGKVVRNELLEKHYKHGSKFLTSFPDGTTQIFYPSGNLAIIRVPNKVNGFTCIVQED 473
  Q5XI56 TISYQLSGDYL--QNVRTEEV--DLQI--TNISITCCDSWKI-CGKVMGNELLEKDYKHGSKFLTSFPDGTIQIFYPSGNLAIIRVPNKTDGFICIIQED 412

  Q7L0X2 MPTNPAILAVLDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRAWNWSNSITS-SP-FVSFKPVFLALNRYIGVRILEQDKISITFLAMGQQARISV 571
  Q5XI56 TATSPAILALFDSSGRSSCYHPNGNVWVYINILGGQYSDQAGNRIRTWNWSS--TKPTPAFVSFKPVLLALNRYIGIRILEQDKVSIHFLAMGQQATICL 510

  Q7L0X2 GTKVKLPNPEEIPILRYVSGDDLLLLASLIKIRRLFHKLEGCVNFPSSQVWEKLKQPSYLSSLSLKLIALCHSSGIKQDIMKTIRNII--NEEI 663
  Q5XI56 GTKVVLQDPEEVPTLRFLSGDDLLLLASLIKIRRLFSKMEGCVNFPVSKAWERLKQPSYLSSLSLKLLALCQNSGIQQNIMETITELIKENE-- 602

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0005543 phospholipid binding
2. P GO:0098978 glutamatergic synapse
2. P GO:0031578 mitotic spindle orientation checkpoint signaling
2. P GO:0005096 GTPase activator activity
2. P GO:0098794 postsynapse
2. P GO:0030425 dendrite
2. P GO:0005816 spindle pole body
2. P GO:0032012 regulation of ARF protein signal transduction
2. P GO:0001100 negative regulation of exit from mitosis
2. P GO:0005085 guanyl-nucleotide exchange factor activity
2. P GO:0046578 regulation of Ras protein signal transduction
2. P GO:1990334 Bfa1-Bub2 complex
2. P GO:0000922 spindle pole
2. P GO:0043025 neuronal cell body
2. P GO:0044732 mitotic spindle pole body
2. P GO:0032154 cleavage furrow
2. P GO:0005092 GDP-dissociation inhibitor activity
2. P GO:0032587 ruffle membrane
3. B GO:0016021 integral component of membrane

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q5W0A0 Glutamate-rich protein 6B 7.13e-03 5.31e-18 7.70e-20
1. PB Q5XI56 Glutamate-rich protein 6 2.97e-08 1.98e-37 0.0
1. PB Q7L0X2 Glutamate-rich protein 6 0 1.97e-166 0.0
1. PB D3Z6S9 Glutamate-rich protein 6 3.12e-05 1.24e-47 0.0
2. P P47113 Mitotic check point protein BFA1 4.79e-01 1.95e-02 NA
2. P P34423 Uncharacterized protein F44B9.2 1.03e-01 1.58e-02 NA
2. P Q9BQI7 PH and SEC7 domain-containing protein 2 3.34e-01 3.15e-02 NA
3. B Q8ND61 Uncharacterized protein C3orf20 3.96e-02 NA 6.48e-12
3. B Q8CDN1 Uncharacterized protein C3orf20 homolog 3.45e-02 NA 1.27e-13