Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PB was
Q5VT03
(NUT family member 2D) with a FATCAT P-Value: 2.45e-05 and RMSD of 15.75 angstrom. The sequence alignment identity is 89.8%.
Structural alignment shown in left. Query protein Q8IVF1 colored as red in alignment, homolog Q5VT03 colored as blue.
Query protein Q8IVF1 is also shown in right top, homolog Q5VT03 showed in right bottom. They are colored based on secondary structures.
Q8IVF1 MEVKGPSGRSFCCESEGQFKSCLKRHTPSLLLPSSWKGNSGSCLMAKALHRMSPTPNSCPLPLPLCRMSGVLCSRNLFT----FKFSLFQLDSGASGEPG 96 Q5VT03 ----------------------------------------------------------------------------MFQEPVYFQIFLFQLDSGASGEPG 24 Q8IVF1 HSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSTLPSTPLVTEQDGCGPS 196 Q5VT03 HSLGLTLGFSHCGNCQTAVVSAQPEGMASNGAYPALGPGVTANPGTSLSVFTALPFTTPAPGPAHGPLLVTAGAPPGGPLVLSNFPSTPLVTEQDGCGPS 124 Q8IVF1 GAGASNVFVQMRTEVGPVKAAQAQTLVLTQAPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQG 296 Q5VT03 GAGASNVFVQMRTEVGPVKAAQAQTLVLTQTPLVWQAPGALCGGVVCPPPLLLAAAPVVPVMAAQVVGGTQACEGGWSQGLPLPPPPPPAAQLPPIVSQG 224 Q8IVF1 NAGPWPQGAHGEGSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRM 396 Q5VT03 NAGPWPQGAHGEGSLASSQAKAPPDDSCNPRSVYENFRLWQHYKPLARRHLPQSPDTEALSCFLIPVLRSLARRKPTMTLEEGLWRAMREWQHTSNFDRM 324 Q8IVF1 IFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLP 496 Q5VT03 IFYEMAEKFLEFEAEEEMQIQKSQWMKGPQCLPPPATPRLEPRGPPAPEVVKQPVYLPSKAGPKAPTACLPPPRPQRPVTKARRPPPRPHRRAETKARLP 424 Q8IVF1 PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDP 596 Q5VT03 PPRPQRPAETKVPEEIPPEVVQEYVDIMEELLGPSLGATGEPEKQREEGEVKQPQEEDWTPPDPGLLSYTDKLCSQKDFVTKVEAVIHPQFLEELLSPDP 524 Q8IVF1 QMDFLALSQELEQEEGLTLAQLVEKRLLPLKEKQHARAAPSRGTARLDSSSSKFAAGQGAERDVPVPQQGVGMETCPPQTTARDSQGRGRAHTGMARSKD 696 Q5VT03 QMDFLALSQELEQEEGLTLAQLVEKRLLPLKEKQHARAAPSRGTARLDSSSSKFAAGQGAERDVPDPQQGVGMETCPPQTTARDSQGRGRAHTGMARSKD 624 Q8IVF1 SVVLLGCQDSPGLRAARPTSPPQDHRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPVPASGLLSPEKWGPQG 796 Q5VT03 SVVLLGCQDSPGLRAARPTSPPQDHRPTCPGVGTKDALDLPGGSPVRESHGLAQGSSEEEELPSLAFLLGSQHKLLPWWLPQSPVPASGLLSPEKWGPQG 724 Q8IVF1 THQFPSAERRGLNLAPSPANKAKKRPLFGSLSPAEKTPHPGPGLRVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQRCSQ 878 Q5VT03 THQSPSAERRGLNLAPSPANKAKKRPLFGSLSPAEKTPHPGPGLRVSGEQSLTWGLGGPSQSQKRKGDPLVSRKEKKQRCSQ 806
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
| Source | GO | Description |
|---|---|---|
| 3. B | GO:0005634 | nucleus |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
| Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
|---|---|---|---|---|---|
| 1. PB | Q5VZR2 | NUT family member 2G | 5.96e-05 | 1.91e-24 | 0.0 |
| 1. PB | Q3V0C3 | NUT family member 2 | 6.83e-03 | 2.93e-18 | 5.74e-138 |
| 1. PB | Q5VT03 | NUT family member 2D | 2.45e-05 | 3.22e-42 | 0.0 |
| 1. PB | A1L443 | NUT family member 2F | 9.66e-05 | 3.74e-28 | 0.0 |
| 1. PB | Q8IVF1 | NUT family member 2A | 0 | 9.63e-149 | 0.0 |
| 1. PB | A6NNL0 | NUT family member 2B | 4.39e-04 | 2.34e-119 | 0.0 |
| 1. PB | B1AL46 | NUT family member 2E | 6.82e-04 | 4.82e-117 | 0.0 |
| 3. B | Q86Y26 | NUT family member 1 | 1.21e-02 | NA | 7.20e-122 |
| 3. B | Q8BHP2 | NUT family member 1 | 6.26e-03 | NA | 6.34e-106 |