Summary

Q8N0W5

Homolog: Q9D498.
Function: IQ domain-containing protein F3.

Statistics

Total GO Annotation: 6
Unique PROST Go: 6
Unique BLAST Go: 0

Total Homologs: 3
Unique PROST Homologs: 2
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was Q9D498 (IQ domain-containing protein F3) with a FATCAT P-Value: 0.0174 and RMSD of 5.56 angstrom. The sequence alignment identity is 19.9%.
Structural alignment shown in left. Query protein Q8N0W5 colored as red in alignment, homolog Q9D498 colored as blue. Query protein Q8N0W5 is also shown in right top, homolog Q9D498 showed in right bottom. They are colored based on secondary structures. 

  Q8N0W5 MAAPRQIPSHIVRLKPSCSTDSSFTRTPVPTVSLASRELPVSSWQ---VT----EPSSKNLWEQICKEYEAEQPPFPEGYKVKQEPVITVAPVEEMLFHG 93
  Q9D498 -----------MEL----DQDKK-KETPEETENV--NEVQLEKQNQDEETEAEAEEADKAILER-SDSVKTECPPQAE--KQNQDEE-TEAEAEE----- 73

  Q8N0W5 FSAEHYFPVSHFTMISRTPCPQDKSETINPKT-CSPKEYLETFIFPVLLPGMASLLHQAKKEKCFERKRTKFIACDFLTEWLYNQNPKRAGEPFTEFFSI 192
  Q9D498 --ADK-------AIL-------ERSDSV--KTECPPQA--E---------------KQIQEEKC----ETQ--EAD-----------RSEG---TE---L 115

  Q8N0W5 PFVEERLKQHPRPPIPLSLLLTEEEAALYIQSFWRACVVRCDPEIQELRQW--QKKLREAK------HIHQQVKIFWAKQEQKVKCKMEDDAVPAAKMKI 284
  Q9D498 GKLHSQLDQ-----LPDNVML----AGVKIQAWWRGTLVRRTLLLAALNAWTIQCWWREAKARLQGRKLHEVMR-YRLRNLN-LK------SI--SKRKQ 196

  Q8N0W5 P--SS-- 287
  Q9D498 PNQSSFL 203

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0001669 acrosomal vesicle
2. P GO:0016592 mediator complex
2. P GO:0005516 calmodulin binding
2. P GO:0045944 positive regulation of transcription by RNA polymerase II
2. P GO:2000344 positive regulation of acrosome reaction
2. P GO:0003712 transcription coregulator activity

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q8N0W5 IQ domain-containing protein K 0 1.26e-138 0.0
2. P Q9D498 IQ domain-containing protein F3 1.74e-02 9.94e-03 NA
2. P A0JLT2 Mediator of RNA polymerase II transcription subunit 19 2.88e-01 2.53e-02 NA