Summary

Q8N128

Homolog: Q8BR63.
Function: Protein FAM177A1.

Statistics

Total GO Annotation: 10
Unique PROST Go: 10
Unique BLAST Go: 0

Total Homologs: 10
Unique PROST Homologs: 6
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 1. PB was Q8BR63 (Protein FAM177A1) with a FATCAT P-Value: 3.08e-14 and RMSD of 2.27 angstrom. The sequence alignment identity is 83.8%.
Structural alignment shown in left. Query protein Q8N128 colored as red in alignment, homolog Q8BR63 colored as blue. Query protein Q8N128 is also shown in right top, homolog Q8BR63 showed in right bottom. They are colored based on secondary structures. 

  Q8N128 MDQEPVGGVERGEAVAASG---AAAAAAFGESAGQMSNERGFENVELGVIGKKKKVPRRVIHFVSGETMEEYSTDEDEVDGLEKKDVLPTVDPTKLTWGP 97
  Q8BR63 MERE--SG------CAAAGETEAAAATAFRDATRQISNERGFENVELGVMGKKKKVPRRVIHFVSGETMEEYSTDEDEVDGLDKKDVLPTVDPTKLTWGP 92

  Q8N128 YLWFYMLRAATSTLSVCDFLGEKIASVLGISTPKYQYAIDEYYRMKKEEEEEEEENRMSEEAEKQYQQNKLQTDSIVQTDQPETVISSSFVNVNFEMEGD 197
  Q8BR63 YLWFYMLRAATSTLSVCDFLGEKIASVLGISTPKYQYAIDEYYRMKKEEEEEEEENRMSEEAERQYQQNKLQADSIVQTDQPETV-SSSFVNINFEMEED 191

  Q8N128 SEVIMESKQNPVSVPP 213
  Q8BR63 CEAIKENKQRPVSVPP 207

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0045040 protein insertion into mitochondrial outer membrane
2. P GO:0006626 protein targeting to mitochondrion
2. P GO:0008320 protein transmembrane transporter activity
2. P GO:0043065 positive regulation of apoptotic process
2. P GO:0005739 mitochondrion
2. P GO:0005741 mitochondrial outer membrane
2. P GO:0016021 integral component of membrane
2. P GO:0005742 mitochondrial outer membrane translocase complex
2. P GO:0030150 protein import into mitochondrial matrix
2. P GO:0051204 protein insertion into mitochondrial membrane

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB A6QLZ5 Protein FAM177A1 8.85e-10 1.08e-59 1.61e-123
1. PB Q8N128 Protein FAM177A1 0 2.98e-131 3.65e-157
1. PB Q8BR63 Protein FAM177A1 3.08e-14 1.59e-52 1.91e-117
1. PB A6PVY3 Protein FAM177B 1.78e-03 5.84e-13 4.94e-27
2. P Q9NS69 Mitochondrial import receptor subunit TOM22 homolog 1.14e-03 1.95e-02 NA
2. P A6QPI6 Mitochondrial import receptor subunit TOM22 homolog 1.36e-02 8.43e-03 NA
2. P Q9CPQ3 Mitochondrial import receptor subunit TOM22 homolog 4.38e-03 3.55e-02 NA
2. P Q75Q41 Mitochondrial import receptor subunit TOM22 homolog 2.56e-03 5.28e-03 NA
2. P O13813 Mitochondrial import receptor subunit tom22 5.47e-03 1.73e-02 NA
2. P Q4R3C7 Mitochondrial import receptor subunit TOM22 homolog 9.57e-03 1.95e-02 NA