Summary

Q8WUB2

Homolog: Q5U1Y9.
Function: Protein FAM216A.

Statistics

Total GO Annotation: 9
Unique PROST Go: 9
Unique BLAST Go: 0

Total Homologs: 10
Unique PROST Homologs: 4
Unique BLAST Homologs: 2

Structures and Sequence Alignment

The best structural homolog that predicted by 1. PB was Q5U1Y9 (Protein FAM216A) with a FATCAT P-Value: 4.01e-06 and RMSD of 3.29 angstrom. The sequence alignment identity is 58.9%.
Structural alignment shown in left. Query protein Q8WUB2 colored as red in alignment, homolog Q5U1Y9 colored as blue. Query protein Q8WUB2 is also shown in right top, homolog Q5U1Y9 showed in right bottom. They are colored based on secondary structures. 

  Q8WUB2 MLGQLLPHTARGLGAAEMPGQGPGSDWTERSSSAEPPAVAGTEGGGGGSAGYSCYQNSKGS------DRIKDGYKVNSHIAKLQELWKTPQNQTIHLSKS 94
  Q5U1Y9 -----------------MPSRCPG--------VAGPPALARTE-GSEGSAGQSYHQNSKGTGEQHKAERIKEGHRMSSHTAKLQELWRTTQIQTIHIPKS 74

  Q8WUB2 MMEASFFKHPDLTTGQKRYLCSIAKIYNANYLKMLMKRQYMHVLQHSSQKPGVLTHHRSRLSSRYSQKQHYPCTTWRHQLEREDS-GSSDIAAASAPEML 193
  Q5U1Y9 MTDASFLKHPELTSGQKRYLCSIAKICNSSYLRTLMKRQYMHLFHHGLQKPGVLTHHRSHISSRYSQKQHSPCTTWRHHLEREDSLG---IAAE-APEMI 170

  Q8WUB2 IQHSLWRPVRNKEGIKTGYASKTRCKSLKIFRRPRKLFMQTVSSDDSESHMSEEKKEEDLLNNFMQSMSIEEQG-EHLMLT----------- 273
  Q5U1Y9 I-HALWRPLRHKEGLKIGYASKTRCKSLKIFRRPGRLFLLPVSSKDYQPCMNDETKEEDLLNECMQSMSIQEQGSSHASLTVSCPTPSSAIP 261

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage
2. P GO:1990904 ribonucleoprotein complex
2. P GO:0071207 histone pre-mRNA stem-loop binding
2. P GO:0045600 positive regulation of fat cell differentiation
2. P GO:0051028 mRNA transport
2. P GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity
2. P GO:0006623 protein targeting to vacuole
2. P GO:0071208 histone pre-mRNA DCP binding
2. P GO:0071204 histone pre-mRNA 3'end processing complex

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q3SZW6 Protein FAM216A 3.88e-04 5.17e-16 3.71e-135
1. PB Q8WUB2 Protein FAM216A 0 2.63e-140 0.0
1. PB Q9DB54 Protein FAM216A 1.76e-03 1.56e-13 1.57e-112
1. PB Q5U1Y9 Protein FAM216A 4.01e-06 2.03e-05 6.31e-111
2. P P38839 Putative cyclin-dependent kinase inhibitor SPL2 4.07e-02 1.16e-02 NA
2. P Q5VYS4 Mesenteric estrogen-dependent adipogenesis protein 4.49e-01 1.79e-04 NA
2. P Q14493 Histone RNA hairpin-binding protein 1.33e-01 3.00e-02 NA
2. P Q14BA6 Mesenteric estrogen-dependent adipogenesis protein 3.91e-01 1.53e-03 NA
3. B Q8N7L0 Protein FAM216B 1.18e-02 NA 7.55e-05
3. B Q17QP0 Protein FAM216B 1.53e-02 NA 0.004