Summary

Q8WW14

Homolog: Q9DAS2.
Function: Protein FAM166C.

Statistics

Total GO Annotation: 13
Unique PROST Go: 13
Unique BLAST Go: 0

Total Homologs: 12
Unique PROST Homologs: 9
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was Q9DAS2 (Protein FAM166C) with a FATCAT P-Value: 0.0417 and RMSD of 1.81 angstrom. The sequence alignment identity is 24.7%.
Structural alignment shown in left. Query protein Q8WW14 colored as red in alignment, homolog Q9DAS2 colored as blue. Query protein Q8WW14 is also shown in right top, homolog Q9DAS2 showed in right bottom. They are colored based on secondary structures. 

  Q8WW14 M--EPSKTFMR--N---LP--ITPGYSGFVP-FLSCQGMSKEDDMNHCVKTFQE--KT---QRYKEQLRELC--CAVATAPKL-KPVNSEETVLQALHQY 82
  Q9DAS2 MAFRSAGTLMTEFNAAFVPPALMPGYKGHVPGVASSFGSSY---GNTTFKYFQDLRNTGLEKSY--AL--LSGGC----FPTIFSP-NS----------- 77

  Q8WW14 NLQYHPLILECKYVKKPLQEPPIPGWAGYL--P---RAKVTEFGCGTRYTVMAKNCYKDFLEITERAKKAHLKPYEEIYGVSSTKTSAPSPKVLQHEE-- 175
  Q9DAS2 -----PLV---------LTDNS-QNWDRWLHQPTYSRSN-QDNGRTTELT----NFYK-----TVQQQR---KYYQD-------KTG-----ILSRVPYF 137

  Q8WW14 LLP-KYPD-FSIP-DGSCPALGRPLREDPKTPLTCGCAQR--P-------SIPCSGKMYLEPLSSAK------YAEG-- 234
  Q9DAS2 VLPVKEPDRYPLPTD--LP----PLSEKSKWNLL-----RLSPDYKRTYQTFP-SGKR----VSSQERQRRDLYFEFRA 200

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0008017 microtubule binding
2. P GO:0005875 microtubule associated complex
2. P GO:0005819 spindle
2. P GO:0051168 nuclear export
2. P GO:0015631 tubulin binding
2. P GO:0031116 positive regulation of microtubule polymerization
2. P GO:0045746 negative regulation of Notch signaling pathway
2. P GO:0007219 Notch signaling pathway
2. P GO:0005829 cytosol
2. P GO:0005634 nucleus
2. P GO:0005874 microtubule
2. P GO:0005200 structural constituent of cytoskeleton
2. P GO:0022008 neurogenesis

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q8WW14 Uncharacterized protein C10orf82 0 5.55e-160 1.17e-174
1. PB A6QPC0 Uncharacterized protein C10orf82 homolog 2.10e-04 9.17e-64 3.31e-118
1. PB Q9CQT6 Uncharacterized protein C10orf82 homolog 1.26e-04 3.62e-55 1.03e-93
2. P Q9DAG4 Testis-expressed sequence 37 protein 7.10e-01 2.32e-02 NA
2. P Q96LM6 Testis-expressed sequence 37 protein 3.97e-01 1.06e-02 NA
2. P A6NJV1 Protein FAM166C 2.07e-01 1.47e-07 NA
2. P A5PJD8 Testis-expressed sequence 37 protein 5.17e-01 4.12e-02 NA
2. P P0CJ62 RBPJ-interacting and tubulin-associated protein 1 4.55e-01 2.73e-03 NA
2. P Q9DAS2 Protein FAM166C 4.17e-02 6.19e-05 NA
2. P P0C875 Protein FAM228B 9.76e-02 1.25e-02 NA
2. P B4QU20 Microtubule-associated protein Jupiter 5.84e-01 1.06e-02 NA
2. P Q5SPV6 Uncharacterized protein C2orf73 homolog 4.57e-01 3.40e-03 NA