Summary

Q8WYQ4

Homolog: P0CH07.
Function: Ubiquitin-60S ribosomal protein L40.

Statistics

Total GO Annotation: 47
Unique PROST Go: 47
Unique BLAST Go: 0

Total Homologs: 71
Unique PROST Homologs: 67
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was P0CH07 (Ubiquitin-60S ribosomal protein L40) with a FATCAT P-Value: 0.00249 and RMSD of 2.62 angstrom. The sequence alignment identity is 24.4%.
Structural alignment shown in left. Query protein Q8WYQ4 colored as red in alignment, homolog P0CH07 colored as blue. Query protein Q8WYQ4 is also shown in right top, homolog P0CH07 showed in right bottom. They are colored based on secondary structures. 

  Q8WYQ4 M--FIKVMFGAGCSVLVNTSCRLVNLTAHLRQKAGLPPDATIALLAEDG-NLVSLEEDLKEGASRAQTMGN-SLLKERAIYVLVRIIKGEDMASTRYESL 96
  P0CH07 MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIFA--GKQL----ED---G--R--TLSDYNIQKESTLHLVLR-LRGGIIEPS----- 81

  Q8WYQ4 LENLDDHYPELAEEL-RR-LSGLSSVGHNWRKRMGTRRGRHEQSPTS--RPRKGPD 148
  P0CH07 LKALASKY-NCEKQICRKCYARLPPRATNCRKK---KCG-H----TNQLRPKKKLK 128

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0051087 chaperone binding
2. P GO:0038183 bile acid signaling pathway
2. P GO:0005047 signal recognition particle binding
2. P GO:0070449 elongin complex
2. P GO:0031466 Cul5-RING ubiquitin ligase complex
2. P GO:0022627 cytosolic small ribosomal subunit
2. P GO:0071816 tail-anchored membrane protein insertion into ER membrane
2. P GO:0005667 transcription regulator complex
2. P GO:0006368 transcription elongation from RNA polymerase II promoter
2. P GO:0031625 ubiquitin protein ligase binding
2. P GO:0005786 signal recognition particle, endoplasmic reticulum targeting
2. P GO:0010942 positive regulation of cell death
2. P GO:0003713 transcription coactivator activity
2. P GO:0008312 7S RNA binding
2. P GO:0003735 structural constituent of ribosome
2. P GO:0031386 protein tag
2. P GO:0005840 ribosome
2. P GO:0042981 regulation of apoptotic process
2. P GO:0006614 SRP-dependent cotranslational protein targeting to membrane
2. P GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane
2. P GO:1903955 positive regulation of protein targeting to mitochondrion
2. P GO:0043657 host cell
2. P GO:0022626 cytosolic ribosome
2. P GO:0016567 protein ubiquitination
2. P GO:0005783 endoplasmic reticulum
2. P GO:0045900 negative regulation of translational elongation
2. P GO:0006915 apoptotic process
2. P GO:0030666 endocytic vesicle membrane
2. P GO:0090200 positive regulation of release of cytochrome c from mitochondria
2. P GO:0019787 ubiquitin-like protein transferase activity
2. P GO:0097202 activation of cysteine-type endopeptidase activity
2. P GO:0005829 cytosol
2. P GO:0005811 lipid droplet
2. P GO:0019941 modification-dependent protein catabolic process
2. P GO:0034389 lipid droplet organization
2. P GO:0005634 nucleus
2. P GO:0030891 VCB complex
2. P GO:0006464 cellular protein modification process
2. P GO:0097194 execution phase of apoptosis
2. P GO:0071818 BAT3 complex
2. P GO:0005785 signal recognition particle receptor complex
2. P GO:0022625 cytosolic large ribosomal subunit
2. P GO:0006412 translation
2. P GO:0031462 Cul2-RING ubiquitin ligase complex
2. P GO:0017085 response to insecticide
2. P GO:0002181 cytoplasmic translation
2. P GO:0005654 nucleoplasm

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB A6NEN9 Uncharacterized protein CXorf65 4.89e-09 1.39e-05 0.002
1. PB Q32LJ3 Uncharacterized protein CXorf65 homolog 6.93e-09 8.53e-17 3.87e-04
1. PB Q8WYQ4 Uncharacterized protein C22orf15 0 5.94e-118 4.30e-107
1. PB Q3V2K1 Uncharacterized protein CXorf65 homolog 2.66e-08 1.33e-13 0.001
2. P P0CH07 Ubiquitin-60S ribosomal protein L40 2.49e-03 1.05e-02 NA
2. P Q7ZWB2 Ubiquitin-like protein 4A 5.29e-03 3.27e-02 NA
2. P P40909 Ubiquitin-60S ribosomal protein L40 2.66e-03 9.81e-03 NA
2. P P0C276 Ubiquitin-60S ribosomal protein L40 2.86e-03 2.56e-02 NA
2. P Q0WPX7 BAG family molecular chaperone regulator 2 5.67e-02 1.11e-03 NA
2. P O04438 Signal recognition particle 9 kDa protein 1.25e-01 3.38e-04 NA
2. P Q15370 Elongin-B 1.21e-01 2.16e-03 NA
2. P P69201 Ubiquitin-60S ribosomal protein L40 3.10e-03 3.59e-02 NA
2. P P33190 Ubiquitin-60S ribosomal protein L40 3.03e-03 2.19e-02 NA
2. P P63053 Ubiquitin-60S ribosomal protein L40 2.78e-03 2.56e-02 NA
2. P B0KWT6 Ubiquitin-like protein 4A 2.70e-02 1.67e-02 NA
2. P Q0D261 Ubiquitin-like protein 4A 4.40e-03 1.21e-03 NA
2. P Q9SMU7 Signal recognition particle 9 kDa protein 7.84e-02 3.22e-04 NA
2. P P46575 Ubiquitin-60S ribosomal protein L40 2.72e-03 5.67e-03 NA
2. P B5X9S9 Ubiquitin-like protein 4A-B 3.15e-03 7.43e-04 NA
2. P A0A3B7TNW2 Crinkler effector protein BLC01 4.71e-02 3.86e-06 NA
2. P Q3T191 Cell death activator CIDE-B 4.79e-02 5.08e-06 NA
2. P B2GV38 Ubiquitin-like protein 4A 4.14e-03 1.30e-02 NA
2. P F1MN90 Cell death activator CIDE-3 1.53e-02 4.13e-04 NA
2. P P49458 Signal recognition particle 9 kDa protein 9.43e-02 1.50e-03 NA
2. P C1BHN7 Ubiquitin-like protein 4A-B 4.04e-03 4.38e-03 NA
2. P C1BXU5 Ubiquitin-like protein 4A 3.81e-03 5.89e-05 NA
2. P Q19KS6 Ubiquitin-like protein 4B 7.42e-03 1.63e-04 NA
2. P P0C275 Ubiquitin-60S ribosomal protein L40 2.87e-03 2.56e-02 NA
2. P P49633 Ubiquitin-60S ribosomal protein L40 2.91e-03 4.79e-03 NA
2. P Q5R4T1 Ubiquitin-like protein 4A 2.73e-02 2.93e-02 NA
2. P C1BGZ8 Ubiquitin-like protein 4A-A 4.17e-03 1.29e-04 NA
2. P Q9SW27 Membrane-anchored ubiquitin-fold protein 3 1.80e-01 1.61e-03 NA
2. P A4QND0 Ubiquitin-like protein 4A 5.37e-03 1.72e-03 NA
2. P P0CH10 Ubiquitin-60S ribosomal protein L40 3.00e-03 3.84e-02 NA
2. P P14794 Ubiquitin-60S ribosomal protein L40 1.02e-02 2.31e-02 NA
2. P B9DHA6 Ubiquitin-60S ribosomal protein L40-1 3.99e-03 4.53e-02 NA
2. P P69200 Ubiquitin-60S ribosomal protein L40 2.72e-03 6.26e-03 NA
2. P Q42202 Ubiquitin-60S ribosomal protein L40-2 3.64e-03 4.53e-02 NA
2. P P62869 Elongin-B 1.29e-02 2.50e-03 NA
2. P P62870 Elongin-B 1.59e-02 2.50e-03 NA
2. P B1MTV8 Ubiquitin-like protein 4A 6.65e-03 1.02e-02 NA
2. P P0DJ25 Ubiquitin-60S ribosomal protein L40 2.83e-03 2.19e-02 NA
2. P F4JDJ0 Heavy metal-associated isoprenylated plant protein 47 1.65e-01 4.03e-02 NA
2. P P0CH11 Ubiquitin-60S ribosomal protein L40 3.46e-03 3.84e-02 NA
2. P P68205 Ubiquitin-60S ribosomal protein L40 2.63e-03 2.56e-02 NA
2. P Q8N7F7 Ubiquitin-like protein 4B 1.03e-02 4.43e-06 NA
2. P B5XFI8 Ubiquitin-like protein 4A-A 4.49e-03 2.63e-04 NA
2. P P0C224 Ubiquitin-60S ribosomal protein L40 2.90e-03 4.93e-02 NA
2. P P11441 Ubiquitin-like protein 4A 2.75e-02 4.66e-03 NA
2. P P21126 Ubiquitin-like protein 4A 4.05e-03 9.15e-03 NA
2. P P62984 Ubiquitin-60S ribosomal protein L40 2.78e-03 2.56e-02 NA
2. P P51423 Ubiquitin-60S ribosomal protein L40 2.94e-03 4.57e-02 NA
2. P P63052 Ubiquitin-60S ribosomal protein L40 2.49e-03 2.56e-02 NA
2. P C3KHF2 Ubiquitin-like protein 4A 3.62e-03 9.90e-03 NA
2. P P0C273 Ubiquitin-60S ribosomal protein L40 2.78e-03 2.56e-02 NA
2. P P63050 Ubiquitin-60S ribosomal protein L40 2.81e-03 2.56e-02 NA
2. P P0CH06 Ubiquitin-60S ribosomal protein L40 3.04e-03 1.05e-02 NA
2. P B7NZQ9 Ubiquitin-like protein 4A 3.13e-03 1.01e-02 NA
2. P O70303 Cell death activator CIDE-B 5.60e-02 2.70e-05 NA
2. P Q4R6I6 Signal recognition particle 9 kDa protein 1.22e-01 2.79e-03 NA
2. P P18101 Ubiquitin-60S ribosomal protein L40 3.01e-03 9.15e-03 NA
2. P P21262 Signal recognition particle 9 kDa protein 1.22e-01 3.22e-03 NA
2. P P63048 Ubiquitin-60S ribosomal protein L40 2.86e-03 2.56e-02 NA
2. P P56198 Cell death activator CIDE-3 3.16e-02 1.34e-05 NA
2. P P62987 Ubiquitin-60S ribosomal protein L40 2.79e-03 2.56e-02 NA
2. P P62986 Ubiquitin-60S ribosomal protein L40 2.84e-03 2.56e-02 NA
2. P Q5XI33 Cell death activator CIDE-3 3.80e-02 1.90e-03 NA
2. P Q9UHD4 Cell death activator CIDE-B 7.16e-02 6.39e-04 NA
2. P Q9CQ84 Ubiquitin-like protein 4B 9.82e-03 9.81e-03 NA
2. P Q2T9Q2 Ubiquitin-like protein 4B 2.67e-03 5.11e-05 NA
2. P P87068 Autophagy-related protein 8 3.81e-02 6.51e-04 NA