Summary

Q969H9

Homolog: Q3T020.
Function: Transcription elongation factor A protein-like 8.

Statistics

Total GO Annotation: 16
Unique PROST Go: 16
Unique BLAST Go: 0

Total Homologs: 14
Unique PROST Homologs: 13
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was Q3T020 (Transcription elongation factor A protein-like 8) with a FATCAT P-Value: 0.00201 and RMSD of 2.27 angstrom. The sequence alignment identity is 19.4%.
Structural alignment shown in left. Query protein Q969H9 colored as red in alignment, homolog Q3T020 colored as blue. Query protein Q969H9 is also shown in right top, homolog Q3T020 showed in right bottom. They are colored based on secondary structures. 

  Q969H9 --------------MPEAHM-QPAKLQTSLPTTDHGSKKP----VSC----YL-PPLSNAHPMCIEVQNAQNCSSAAATLEP-SIISDTCFYKPITKDQL 75
  Q3T020 MQKSCGENERKPQNMPKAEEDRP--LE-AVPQEAEGNPQPSEEGVSQEAEGNLRGGLTQ--P-----GQGYKEDSPVRHLDPEEMIRGA--------DEL 82

  Q969H9 SS-RSELNTVRLKCLNSLRGWKILNQLSLT--------- 104
  Q3T020 ERLREEIRRVRNKFV--MMHWK--QRHSRSRPYPVCFRP 117

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0042025 host cell nucleus
2. P GO:0031423 hexon binding
2. P GO:0039526 modulation by virus of host apoptotic process
2. P GO:0046718 viral entry into host cell
2. P GO:0098021 viral capsid, decoration
2. P GO:0044192 host cell mitochondrial inner membrane
2. P GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process
2. P GO:0005102 signaling receptor binding
2. P GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors
2. P GO:0044164 host cell cytosol
2. P GO:0005163 nerve growth factor receptor binding
2. P GO:0050699 WW domain binding
2. P GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process
2. P GO:0007165 signal transduction
2. P GO:0039545 suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity
2. P GO:0007275 multicellular organism development

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q969H9 Disrupted in renal carcinoma protein 1 0 2.30e-135 5.36e-73
2. P Q00994 Protein BEX3 6.82e-03 1.86e-02 NA
2. P P03414 Putative uncharacterized protein PXBL-III (Fragment) NA 2.73e-02 NA
2. P Q6ZUT4 Putative uncharacterized protein FLJ43343 3.07e-01 4.52e-02 NA
2. P Q86SY8 Putative uncharacterized protein KTN1-AS1 2.02e-01 6.42e-05 NA
2. P Q9GZL8 Putative BPES syndrome breakpoint region protein 1.70e-01 5.29e-03 NA
2. P Q5H9J7 Protein BEX5 3.00e-02 3.39e-04 NA
2. P Q3T020 Transcription elongation factor A protein-like 8 2.01e-03 2.55e-03 NA
2. P Q9UH64 Putative protein CDKN2A-DT 5.52e-02 1.76e-02 NA
2. P Q55G14 Putative uncharacterized protein DDB_G0268370 5.20e-01 3.10e-02 NA
2. P P32539 Hexon-interlacing protein NA 1.12e-02 NA
2. P Q8T2Q8 Uncharacterized protein DDB_G0275137 1.62e-02 2.08e-02 NA
2. P Q0A428 Protein PB1-F2 NA 4.65e-02 NA
2. P A6NJI1 Uncharacterized protein C11orf86 4.80e-03 2.06e-02 NA