Summary

Q96BT1

Homolog: Q6CVS3.
Function: Transcriptional regulatory protein LGE1.

Statistics

Total GO Annotation: 97
Unique PROST Go: 90
Unique BLAST Go: 6

Total Homologs: 60
Unique PROST Homologs: 58
Unique BLAST Homologs: 1

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was Q6CVS3 (Transcriptional regulatory protein LGE1) with a FATCAT P-Value: 0.000255 and RMSD of 3.43 angstrom. The sequence alignment identity is 20.9%.
Structural alignment shown in left. Query protein Q96BT1 colored as red in alignment, homolog Q6CVS3 colored as blue. Query protein Q96BT1 is also shown in right top, homolog Q6CVS3 showed in right bottom. They are colored based on secondary structures.

  Q96BT1 MAQPQLYLPEPFKIAYRKVGQCRRFQQLKKKNGSFKRKGIERWHRAVSTNLLKQNVLVPKEESS--SD----SDMGFHESQQNQKSNLKTKVKTAFG--R 92
  Q6CVS3 MSEPN----EG-GSSYRSGGN---Y------NG-YKPSG-NRY----QPN--SNNRGPPRYRSNHRQDGGYYNNGGYHQ-QQGYGYGQPTH---AHGVQR 74

  Q96BT1 MLSYK---YRSKPACASQEG--STDHKEALLSNTQSLLPRIVKEFSSPKLFTAKMRKLSENATIQLDVVEAETEEITQGNTLLRARRTTKRLSVTSLPSG 187
  Q6CVS3 Q-TYRGGSYHPYQHSDSRYGSNSTYRRP---YGQQSVPP-------APPPSTA--SSVSSSS------------AYSRGSNVLPVSR-------NSYPS- 141

  Q96BT1 LQKGP-Y-SPKKRPHFPALKKKKRGMEN----ILRKSDLT-VGKLQ--MQVDDLIETVTDKSMKL-LAQRHAEL----QQCEFLGDEI-LQSSKQFQRIS 272
  Q6CVS3 ----PKYEQPKKK--F-TIPKD----ENPFIYMMSNDDHSRTSKLKEVYKENDQIDNKLEE-LKLKIFKDELELGLMSTQCE--KDALNVQLTQ--EKLD 225

  Q96BT1 KRTMRKYKLKNMTTKGPGDS 292
  Q6CVS3 SLLMN--------------- 230

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
1. PB GO:0007165 signal transduction
2. P GO:0009556 microsporogenesis
2. P GO:0005096 GTPase activator activity
2. P GO:0090141 positive regulation of mitochondrial fission
2. P GO:0019904 protein domain specific binding
2. P GO:0030374 nuclear receptor coactivator activity
2. P GO:0019031 viral envelope
2. P GO:0051020 GTPase binding
2. P GO:0046601 positive regulation of centriole replication
2. P GO:0090314 positive regulation of protein targeting to membrane
2. P GO:0030430 host cell cytoplasm
2. P GO:0034501 protein localization to kinetochore
2. P GO:0071469 cellular response to alkaline pH
2. P GO:0034080 CENP-A containing chromatin assembly
2. P GO:0051285 cell cortex of cell tip
2. P GO:0009909 regulation of flower development
2. P GO:0038202 TORC1 signaling
2. P GO:0003713 transcription coactivator activity
2. P GO:0006626 protein targeting to mitochondrion
2. P GO:0043966 histone H3 acetylation
2. P GO:0034451 centriolar satellite
2. P GO:0072686 mitotic spindle
2. P GO:0030991 intraciliary transport particle A
2. P GO:0051321 meiotic cell cycle
2. P GO:0000779 condensed chromosome, centromeric region
2. P GO:0007142 male meiosis II
2. P GO:0032467 positive regulation of cytokinesis
2. P GO:0051123 RNA polymerase II preinitiation complex assembly
2. P GO:0000791 euchromatin
2. P GO:0071894 histone H2B conserved C-terminal lysine ubiquitination
2. P GO:0005634 nucleus
2. P GO:0032120 ascospore-type prospore membrane formation
2. P GO:1900244 positive regulation of synaptic vesicle endocytosis
2. P GO:0031031 positive regulation of septation initiation signaling
2. P GO:0019033 viral tegument
2. P GO:0008053 mitochondrial fusion
2. P GO:0031647 regulation of protein stability
2. P GO:0030435 sporulation resulting in formation of a cellular spore
2. P GO:0000306 extrinsic component of vacuolar membrane
2. P GO:0016922 nuclear receptor binding
2. P GO:0030914
2. P GO:0000070 mitotic sister chromatid segregation
2. P GO:0043009 chordate embryonic development
2. P GO:0033276 transcription factor TFTC complex
2. P GO:0071472 cellular response to salt stress
2. P GO:1905758 positive regulation of primary cell septum biogenesis
2. P GO:0005628 prospore membrane
2. P GO:0000818 nuclear MIS12/MIND complex
2. P GO:0006357 regulation of transcription by RNA polymerase II
2. P GO:0046628 positive regulation of insulin receptor signaling pathway
2. P GO:0031097 medial cortex
2. P GO:0070584 mitochondrion morphogenesis
2. P GO:0051455 monopolar spindle attachment to meiosis I kinetochore
2. P GO:0000235 astral microtubule
2. P GO:0033503 HULC complex
2. P GO:0042763 intracellular immature spore
2. P GO:0045104 intermediate filament cytoskeleton organization
2. P GO:0005794 Golgi apparatus
2. P GO:0035721 intraciliary retrograde transport
2. P GO:0007124 pseudohyphal growth
2. P GO:0001932 regulation of protein phosphorylation
2. P GO:0000278 mitotic cell cycle
2. P GO:0032153 cell division site
2. P GO:0000124 SAGA complex
2. P GO:0031929 TOR signaling
2. P GO:0043967 histone H4 acetylation
2. P GO:0070847 core mediator complex
2. P GO:0010628 positive regulation of gene expression
2. P GO:1902426 deactivation of mitotic spindle assembly checkpoint
2. P GO:0003712 transcription coregulator activity
2. P GO:0031931 TORC1 complex
2. P GO:0042254 ribosome biogenesis
2. P GO:0003968 RNA-directed 5'-3' RNA polymerase activity
2. P GO:0005816 spindle pole body
2. P GO:0031105 septin complex
2. P GO:0031617 NMS complex
2. P GO:0090043 regulation of tubulin deacetylation
2. P GO:0031063 regulation of histone deacetylation
2. P GO:0016592 mediator complex
2. P GO:0000939 inner kinetochore
2. P GO:0000164 protein phosphatase type 1 complex
2. P GO:0000776 kinetochore
2. P GO:0010666 positive regulation of cardiac muscle cell apoptotic process
2. P GO:0005671 obsolete Ada2/Gcn5/Ada3 transcription activator complex
2. P GO:0045724 positive regulation of cilium assembly
2. P GO:0045893 positive regulation of transcription, DNA-templated
2. P GO:0030520 intracellular estrogen receptor signaling pathway
2. P GO:1902412 regulation of mitotic cytokinesis
2. P GO:0044204 host cell nuclear matrix
2. P GO:0005654 nucleoplasm
2. P GO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter
3. B GO:0035556 intracellular signal transduction
3. B GO:0007168 receptor guanylyl cyclase signaling pathway
3. B GO:0004672 protein kinase activity
3. B GO:0004383 guanylate cyclase activity
3. B GO:0006182 cGMP biosynthetic process
3. B GO:0001653 peptide receptor activity

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q96BT1 Putative uncharacterized protein C3orf49 0 1.91e-133 0.0
2. P O75528 Transcriptional adapter 3 1.40e-02 3.10e-02 NA
2. P Q5XIG5 G kinase-anchoring protein 1 2.27e-01 4.85e-02 NA
2. P Q197A4 Uncharacterized protein 056L NA 3.54e-02 NA
2. P Q5M8L3 G kinase-anchoring protein 1 3.22e-02 6.93e-03 NA
2. P Q6GQV1 INSYN2B protein 6.58e-02 1.35e-02 NA
2. P Q8B9Q8 Phosphoprotein NA 3.04e-02 NA
2. P P38280 Spore-specific protein YSW1 9.68e-02 3.04e-02 NA
2. P Q12493 Inner kinetochore subunit NKP1 3.81e-02 2.74e-03 NA
2. P D3YPD5 Virion protein US10 NA 1.31e-02 NA
2. P B8AE37 Protein HEADING DATE REPRESSOR 1 2.02e-03 1.65e-03 NA
2. P Q9UUI2 Small histone ubiquitination factor 1 1.22e-03 3.54e-04 NA
2. P Q6PCP5 Mitochondrial fission factor 1.01e-02 3.58e-02 NA
2. P Q13352 Centromere protein R 2.20e-03 8.77e-03 NA
2. P P39650 Prespore-specific transcriptional regulator RsfA 3.02e-02 2.47e-02 NA
2. P Q9UTR4 Septation protein etd1 1.75e-02 8.03e-05 NA
2. P B1JR11 Der GTPase-activating protein YihI 1.33e-01 1.58e-02 NA
2. P P07242 Late transcription elongation factor H5 NA 2.46e-03 NA
2. P Q32LE2 G kinase-anchoring protein 1 6.17e-02 3.61e-02 NA
2. P Q03898 Filament protein FIN1 2.06e-01 6.63e-05 NA
2. P Q96QU4 Protein FRG2-like-1 5.07e-03 1.74e-02 NA
2. P P0CO77 Mediator of RNA polymerase II transcription subunit 7 8.78e-03 2.13e-02 NA
2. P Q5VSY0 G kinase-anchoring protein 1 2.90e-01 3.98e-02 NA
2. P A1XIQ0 Uncharacterized protein ORF1 NA 4.59e-02 NA
2. P P33062 Late transcription elongation factor H5 NA 9.63e-03 NA
2. P Q12507 Superficial pseudohyphal growth protein 1 1.68e-01 1.86e-02 NA
2. P Q6K678 Protein HEADING DATE REPRESSOR 1 5.19e-03 1.65e-03 NA
2. P Q8C4M7 Centromere protein U 5.04e-02 1.14e-02 NA
2. P Q9UUB5 Kinetochore protein mis13 7.42e-02 1.98e-02 NA
2. P Q8IQQ4 RAB6-interacting golgin 3.12e-03 2.10e-03 NA
2. P Q8R0L9 Transcriptional adapter 3 1.72e-02 2.09e-02 NA
2. P Q4V8G7 Centromere protein U 2.05e-03 2.27e-04 NA
2. P Q4V8F5 Transcriptional adapter 3 2.58e-02 2.09e-02 NA
2. P Q8BP99 UPF0500 protein C1orf216 homolog 1.08e-04 5.41e-03 NA
2. P O55722 Uncharacterized protein 101L NA 1.16e-02 NA
2. P A6NGY1 Protein FRG2-like-2 8.69e-04 6.30e-03 NA
2. P Q99332 Protein HPH1 2.02e-02 2.68e-02 NA
2. P P89468 Tegument protein VP22 NA 2.21e-02 NA
2. P Q66JG5 Transcriptional adapter 3 1.50e-01 4.16e-02 NA
2. P Q71F23 Centromere protein U 2.22e-03 1.20e-04 NA
2. P P32788 Uncharacterized protein YBL010C 1.25e-02 2.63e-02 NA
2. P A6VLB1 Der GTPase-activating protein YihI 3.66e-01 1.38e-02 NA
2. P Q5MKM7 Phosphoprotein NA 6.37e-07 NA
2. P Q5EAE2 Transcriptional adapter 3 1.56e-02 3.10e-02 NA
2. P Q08921 Target of rapamycin complex 1 subunit TCO89 2.35e-01 5.52e-03 NA
2. P Q2TBN9 Intraflagellar transport protein 43 homolog 1.71e-01 1.37e-02 NA
2. P P33308 Mediator of RNA polymerase II transcription subunit 9 2.92e-02 4.30e-04 NA
2. P Q9LM24 Protein FLOURY 1-like 1.36e-02 6.24e-03 NA
2. P O74428 Target of rapamycin complex 1 subunit tco89 1.21e-02 2.73e-04 NA
2. P P0CO76 Mediator of RNA polymerase II transcription subunit 7 5.35e-03 2.13e-02 NA
2. P O60104 Mediator of RNA polymerase II transcription subunit 7 5.12e-02 9.45e-03 NA
2. P F4IDQ5 Protein JASON 8.71e-02 3.33e-02 NA
2. P Q6BHS5 Protein ATC1/LIC4 1.29e-02 6.92e-04 NA
2. P Q6GP48 Mitochondrial fission regulator 1-like-A 3.63e-01 4.05e-02 NA
2. P P20538 Late transcription elongation factor H5 NA 1.60e-03 NA
2. P Q6CVS3 Transcriptional regulatory protein LGE1 2.55e-04 3.58e-02 NA
2. P Q65W23 Der GTPase-activating protein YihI 3.65e-01 5.36e-03 NA
2. P Q6CN40 Topoisomerase I damage affected protein 11 6.39e-03 4.47e-03 NA
2. P Q04839 mRNA transport factor GFD1 9.10e-03 1.05e-02 NA
3. B P55205 Guanylate cyclase 2G 6.53e-01 NA 0.048