Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 2. P was
Q6CVS3
(Transcriptional regulatory protein LGE1) with a FATCAT P-Value: 0.000255 and RMSD of 3.43 angstrom. The sequence alignment identity is 20.9%.
Structural alignment shown in left. Query protein Q96BT1 colored as red in alignment, homolog Q6CVS3 colored as blue.
Query protein Q96BT1 is also shown in right top, homolog Q6CVS3 showed in right bottom. They are colored based on secondary structures.
Q96BT1 MAQPQLYLPEPFKIAYRKVGQCRRFQQLKKKNGSFKRKGIERWHRAVSTNLLKQNVLVPKEESS--SD----SDMGFHESQQNQKSNLKTKVKTAFG--R 92 Q6CVS3 MSEPN----EG-GSSYRSGGN---Y------NG-YKPSG-NRY----QPN--SNNRGPPRYRSNHRQDGGYYNNGGYHQ-QQGYGYGQPTH---AHGVQR 74 Q96BT1 MLSYK---YRSKPACASQEG--STDHKEALLSNTQSLLPRIVKEFSSPKLFTAKMRKLSENATIQLDVVEAETEEITQGNTLLRARRTTKRLSVTSLPSG 187 Q6CVS3 Q-TYRGGSYHPYQHSDSRYGSNSTYRRP---YGQQSVPP-------APPPSTA--SSVSSSS------------AYSRGSNVLPVSR-------NSYPS- 141 Q96BT1 LQKGP-Y-SPKKRPHFPALKKKKRGMEN----ILRKSDLT-VGKLQ--MQVDDLIETVTDKSMKL-LAQRHAEL----QQCEFLGDEI-LQSSKQFQRIS 272 Q6CVS3 ----PKYEQPKKK--F-TIPKD----ENPFIYMMSNDDHSRTSKLKEVYKENDQIDNKLEE-LKLKIFKDELELGLMSTQCE--KDALNVQLTQ--EKLD 225 Q96BT1 KRTMRKYKLKNMTTKGPGDS 292 Q6CVS3 SLLMN--------------- 230
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source | GO | Description |
---|---|---|
1. PB | GO:0007165 | signal transduction |
2. P | GO:0009556 | microsporogenesis |
2. P | GO:0005096 | GTPase activator activity |
2. P | GO:0090141 | positive regulation of mitochondrial fission |
2. P | GO:0019904 | protein domain specific binding |
2. P | GO:0030374 | nuclear receptor coactivator activity |
2. P | GO:0019031 | viral envelope |
2. P | GO:0051020 | GTPase binding |
2. P | GO:0046601 | positive regulation of centriole replication |
2. P | GO:0090314 | positive regulation of protein targeting to membrane |
2. P | GO:0030430 | host cell cytoplasm |
2. P | GO:0034501 | protein localization to kinetochore |
2. P | GO:0071469 | cellular response to alkaline pH |
2. P | GO:0034080 | CENP-A containing chromatin assembly |
2. P | GO:0051285 | cell cortex of cell tip |
2. P | GO:0009909 | regulation of flower development |
2. P | GO:0038202 | TORC1 signaling |
2. P | GO:0003713 | transcription coactivator activity |
2. P | GO:0006626 | protein targeting to mitochondrion |
2. P | GO:0043966 | histone H3 acetylation |
2. P | GO:0034451 | centriolar satellite |
2. P | GO:0072686 | mitotic spindle |
2. P | GO:0030991 | intraciliary transport particle A |
2. P | GO:0051321 | meiotic cell cycle |
2. P | GO:0000779 | condensed chromosome, centromeric region |
2. P | GO:0007142 | male meiosis II |
2. P | GO:0032467 | positive regulation of cytokinesis |
2. P | GO:0051123 | RNA polymerase II preinitiation complex assembly |
2. P | GO:0000791 | euchromatin |
2. P | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination |
2. P | GO:0005634 | nucleus |
2. P | GO:0032120 | ascospore-type prospore membrane formation |
2. P | GO:1900244 | positive regulation of synaptic vesicle endocytosis |
2. P | GO:0031031 | positive regulation of septation initiation signaling |
2. P | GO:0019033 | viral tegument |
2. P | GO:0008053 | mitochondrial fusion |
2. P | GO:0031647 | regulation of protein stability |
2. P | GO:0030435 | sporulation resulting in formation of a cellular spore |
2. P | GO:0000306 | extrinsic component of vacuolar membrane |
2. P | GO:0016922 | nuclear receptor binding |
2. P | GO:0030914 | |
2. P | GO:0000070 | mitotic sister chromatid segregation |
2. P | GO:0043009 | chordate embryonic development |
2. P | GO:0033276 | transcription factor TFTC complex |
2. P | GO:0071472 | cellular response to salt stress |
2. P | GO:1905758 | positive regulation of primary cell septum biogenesis |
2. P | GO:0005628 | prospore membrane |
2. P | GO:0000818 | nuclear MIS12/MIND complex |
2. P | GO:0006357 | regulation of transcription by RNA polymerase II |
2. P | GO:0046628 | positive regulation of insulin receptor signaling pathway |
2. P | GO:0031097 | medial cortex |
2. P | GO:0070584 | mitochondrion morphogenesis |
2. P | GO:0051455 | monopolar spindle attachment to meiosis I kinetochore |
2. P | GO:0000235 | astral microtubule |
2. P | GO:0033503 | HULC complex |
2. P | GO:0042763 | intracellular immature spore |
2. P | GO:0045104 | intermediate filament cytoskeleton organization |
2. P | GO:0005794 | Golgi apparatus |
2. P | GO:0035721 | intraciliary retrograde transport |
2. P | GO:0007124 | pseudohyphal growth |
2. P | GO:0001932 | regulation of protein phosphorylation |
2. P | GO:0000278 | mitotic cell cycle |
2. P | GO:0032153 | cell division site |
2. P | GO:0000124 | SAGA complex |
2. P | GO:0031929 | TOR signaling |
2. P | GO:0043967 | histone H4 acetylation |
2. P | GO:0070847 | core mediator complex |
2. P | GO:0010628 | positive regulation of gene expression |
2. P | GO:1902426 | deactivation of mitotic spindle assembly checkpoint |
2. P | GO:0003712 | transcription coregulator activity |
2. P | GO:0031931 | TORC1 complex |
2. P | GO:0042254 | ribosome biogenesis |
2. P | GO:0003968 | RNA-directed 5'-3' RNA polymerase activity |
2. P | GO:0005816 | spindle pole body |
2. P | GO:0031105 | septin complex |
2. P | GO:0031617 | NMS complex |
2. P | GO:0090043 | regulation of tubulin deacetylation |
2. P | GO:0031063 | regulation of histone deacetylation |
2. P | GO:0016592 | mediator complex |
2. P | GO:0000939 | inner kinetochore |
2. P | GO:0000164 | protein phosphatase type 1 complex |
2. P | GO:0000776 | kinetochore |
2. P | GO:0010666 | positive regulation of cardiac muscle cell apoptotic process |
2. P | GO:0005671 | obsolete Ada2/Gcn5/Ada3 transcription activator complex |
2. P | GO:0045724 | positive regulation of cilium assembly |
2. P | GO:0045893 | positive regulation of transcription, DNA-templated |
2. P | GO:0030520 | intracellular estrogen receptor signaling pathway |
2. P | GO:1902412 | regulation of mitotic cytokinesis |
2. P | GO:0044204 | host cell nuclear matrix |
2. P | GO:0005654 | nucleoplasm |
2. P | GO:0060261 | positive regulation of transcription initiation from RNA polymerase II promoter |
3. B | GO:0035556 | intracellular signal transduction |
3. B | GO:0007168 | receptor guanylyl cyclase signaling pathway |
3. B | GO:0004672 | protein kinase activity |
3. B | GO:0004383 | guanylate cyclase activity |
3. B | GO:0006182 | cGMP biosynthetic process |
3. B | GO:0001653 | peptide receptor activity |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
---|---|---|---|---|---|
1. PB | Q96BT1 | Putative uncharacterized protein C3orf49 | 0 | 1.91e-133 | 0.0 |
2. P | O75528 | Transcriptional adapter 3 | 1.40e-02 | 3.10e-02 | NA |
2. P | Q5XIG5 | G kinase-anchoring protein 1 | 2.27e-01 | 4.85e-02 | NA |
2. P | Q197A4 | Uncharacterized protein 056L | NA | 3.54e-02 | NA |
2. P | Q5M8L3 | G kinase-anchoring protein 1 | 3.22e-02 | 6.93e-03 | NA |
2. P | Q6GQV1 | INSYN2B protein | 6.58e-02 | 1.35e-02 | NA |
2. P | Q8B9Q8 | Phosphoprotein | NA | 3.04e-02 | NA |
2. P | P38280 | Spore-specific protein YSW1 | 9.68e-02 | 3.04e-02 | NA |
2. P | Q12493 | Inner kinetochore subunit NKP1 | 3.81e-02 | 2.74e-03 | NA |
2. P | D3YPD5 | Virion protein US10 | NA | 1.31e-02 | NA |
2. P | B8AE37 | Protein HEADING DATE REPRESSOR 1 | 2.02e-03 | 1.65e-03 | NA |
2. P | Q9UUI2 | Small histone ubiquitination factor 1 | 1.22e-03 | 3.54e-04 | NA |
2. P | Q6PCP5 | Mitochondrial fission factor | 1.01e-02 | 3.58e-02 | NA |
2. P | Q13352 | Centromere protein R | 2.20e-03 | 8.77e-03 | NA |
2. P | P39650 | Prespore-specific transcriptional regulator RsfA | 3.02e-02 | 2.47e-02 | NA |
2. P | Q9UTR4 | Septation protein etd1 | 1.75e-02 | 8.03e-05 | NA |
2. P | B1JR11 | Der GTPase-activating protein YihI | 1.33e-01 | 1.58e-02 | NA |
2. P | P07242 | Late transcription elongation factor H5 | NA | 2.46e-03 | NA |
2. P | Q32LE2 | G kinase-anchoring protein 1 | 6.17e-02 | 3.61e-02 | NA |
2. P | Q03898 | Filament protein FIN1 | 2.06e-01 | 6.63e-05 | NA |
2. P | Q96QU4 | Protein FRG2-like-1 | 5.07e-03 | 1.74e-02 | NA |
2. P | P0CO77 | Mediator of RNA polymerase II transcription subunit 7 | 8.78e-03 | 2.13e-02 | NA |
2. P | Q5VSY0 | G kinase-anchoring protein 1 | 2.90e-01 | 3.98e-02 | NA |
2. P | A1XIQ0 | Uncharacterized protein ORF1 | NA | 4.59e-02 | NA |
2. P | P33062 | Late transcription elongation factor H5 | NA | 9.63e-03 | NA |
2. P | Q12507 | Superficial pseudohyphal growth protein 1 | 1.68e-01 | 1.86e-02 | NA |
2. P | Q6K678 | Protein HEADING DATE REPRESSOR 1 | 5.19e-03 | 1.65e-03 | NA |
2. P | Q8C4M7 | Centromere protein U | 5.04e-02 | 1.14e-02 | NA |
2. P | Q9UUB5 | Kinetochore protein mis13 | 7.42e-02 | 1.98e-02 | NA |
2. P | Q8IQQ4 | RAB6-interacting golgin | 3.12e-03 | 2.10e-03 | NA |
2. P | Q8R0L9 | Transcriptional adapter 3 | 1.72e-02 | 2.09e-02 | NA |
2. P | Q4V8G7 | Centromere protein U | 2.05e-03 | 2.27e-04 | NA |
2. P | Q4V8F5 | Transcriptional adapter 3 | 2.58e-02 | 2.09e-02 | NA |
2. P | Q8BP99 | UPF0500 protein C1orf216 homolog | 1.08e-04 | 5.41e-03 | NA |
2. P | O55722 | Uncharacterized protein 101L | NA | 1.16e-02 | NA |
2. P | A6NGY1 | Protein FRG2-like-2 | 8.69e-04 | 6.30e-03 | NA |
2. P | Q99332 | Protein HPH1 | 2.02e-02 | 2.68e-02 | NA |
2. P | P89468 | Tegument protein VP22 | NA | 2.21e-02 | NA |
2. P | Q66JG5 | Transcriptional adapter 3 | 1.50e-01 | 4.16e-02 | NA |
2. P | Q71F23 | Centromere protein U | 2.22e-03 | 1.20e-04 | NA |
2. P | P32788 | Uncharacterized protein YBL010C | 1.25e-02 | 2.63e-02 | NA |
2. P | A6VLB1 | Der GTPase-activating protein YihI | 3.66e-01 | 1.38e-02 | NA |
2. P | Q5MKM7 | Phosphoprotein | NA | 6.37e-07 | NA |
2. P | Q5EAE2 | Transcriptional adapter 3 | 1.56e-02 | 3.10e-02 | NA |
2. P | Q08921 | Target of rapamycin complex 1 subunit TCO89 | 2.35e-01 | 5.52e-03 | NA |
2. P | Q2TBN9 | Intraflagellar transport protein 43 homolog | 1.71e-01 | 1.37e-02 | NA |
2. P | P33308 | Mediator of RNA polymerase II transcription subunit 9 | 2.92e-02 | 4.30e-04 | NA |
2. P | Q9LM24 | Protein FLOURY 1-like | 1.36e-02 | 6.24e-03 | NA |
2. P | O74428 | Target of rapamycin complex 1 subunit tco89 | 1.21e-02 | 2.73e-04 | NA |
2. P | P0CO76 | Mediator of RNA polymerase II transcription subunit 7 | 5.35e-03 | 2.13e-02 | NA |
2. P | O60104 | Mediator of RNA polymerase II transcription subunit 7 | 5.12e-02 | 9.45e-03 | NA |
2. P | F4IDQ5 | Protein JASON | 8.71e-02 | 3.33e-02 | NA |
2. P | Q6BHS5 | Protein ATC1/LIC4 | 1.29e-02 | 6.92e-04 | NA |
2. P | Q6GP48 | Mitochondrial fission regulator 1-like-A | 3.63e-01 | 4.05e-02 | NA |
2. P | P20538 | Late transcription elongation factor H5 | NA | 1.60e-03 | NA |
2. P | Q6CVS3 | Transcriptional regulatory protein LGE1 | 2.55e-04 | 3.58e-02 | NA |
2. P | Q65W23 | Der GTPase-activating protein YihI | 3.65e-01 | 5.36e-03 | NA |
2. P | Q6CN40 | Topoisomerase I damage affected protein 11 | 6.39e-03 | 4.47e-03 | NA |
2. P | Q04839 | mRNA transport factor GFD1 | 9.10e-03 | 1.05e-02 | NA |
3. B | P55205 | Guanylate cyclase 2G | 6.53e-01 | NA | 0.048 |