Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PB was
Q8N328
(PiggyBac transposable element-derived protein 3) with a FATCAT P-Value: 1.42e-13 and RMSD of 2.87 angstrom. The sequence alignment identity is 26.9%.
Structural alignment shown in left. Query protein Q96DM1 colored as red in alignment, homolog Q8N328 colored as blue.
Query protein Q96DM1 is also shown in right top, homolog Q8N328 showed in right bottom. They are colored based on secondary structures.
Q96DM1 --------------------------MSNPRKRSIPMRDSNTG------LEQL----------LAEDSFD-ESDFSEIDD-----SDNFSDSALEADKIR 52 Q8N328 MPRTLSLHEITDLLETDDSIEASAIVIQPPENATAPVSDEESGDEEGGTINNLPGSLLHTAAYLIQDGSDAESD-S--DDPSYAPKD---DS---PDEV- 90 Q96DM1 PLSH-LESDGKSSTSSDSGRSM-----KWSARAMIPRQRYDFTGTP--GRKVDV--SD-IT---DPLQYFELFFTEELVSKITRETNAQAALLASKPPGP 138 Q8N328 PSTFTVQQPPPSRR-----RKMTKILCKWK-KA-------DLTVQPVAGR-VTAPPNDFFTVMRTPTEILELFLDDEVIELIVKYSNLYA---CSK--GV 171 Q96DM1 K-GFSRMDKWKDTDNDELKVFFAVMLLQGIVQKPELEMFWSTRPLLDTPYLRQIMTGERFLLLFRCLHFVNNSSISAGQSKAQISLQKIKPVFDFLVNKF 237 Q8N328 HLGL--------T-SSEFKCFLGIIFLSGYVSVPRRRMFWEQRTDVHNVLVSAAMRRDRFETIFSNLHVADNANLDP-VDK----FSKLRPLISKL-NER 256 Q96DM1 STVYTPNRN-IAVDESLML-FKGPLAMKQYLPTKRVRFGLKLYVLC-ESQSGYV-W-NALVHTGPGMNLKDSADGLKSSRIVLTLVNDLL-----GQGYC 327 Q8N328 CMKFVPNETYFSFDE-FMVPYFGRHGCKQFIRGKPIRFGYKFW--CGATCLGYICWFQP--YQGKNPNTKHEEYGVGAS-LVLQ-FSEALTEAHPGQYHF 349 Q96DM1 VFLDNFNISPMLFREL----HQNRTDAVGTAR---LNRKQIPND--LKKRIAKGTTVARFCGE--LMALKWCDGKEVTMLST---FHNDTVIEVNNRNGK 413 Q8N328 VF-NNFFTSIALLDKLSSMGHQ----ATGTVRKDHIDRVPLESDVALKKK-ERGTFDYRIDGKGNIVC-RWNDNSVVTVASSGAGIHPLCLV---SRYSQ 439 Q96DM1 KTKR------PRVIVDYNENMGAVDSADQMLTSYPSERK--RHKVWYKKFFHHLL---HITVLNSYILFKK-DNPEHTMSHINFRLALIERMLEKH-H-- 498 Q8N328 KLKKKIQVQQPNMIKVYNQFMGGVDRADENIDKY---RASIRGKKWYSS---PLLFCFELVLQNAWQLHKTYD--EKPVDFLEFRRRVVCHYLETHGHPP 531 Q96DM1 KPGQQHLRGRPCS---DDVTPLRLSG-RHFPKSIPATSGKQNPTGRCKICCSQYDKDGKKIRKETRYFCAECDVPLCVVPC-FEIYHTKKNY 585 Q8N328 EPGQ---KGRPQKRNIDS----RYDGINH----VIVKQGKQ--T-RCAEC-----------HKNTTFRCEKCDVAL-HVKCSVE-YHTE--- 593
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
| Source | GO | Description |
|---|---|---|
| 1. PB | GO:0016604 | nuclear body |
| 1. PB | GO:0004803 | transposase activity |
| 1. PB | GO:0004519 | endonuclease activity |
| 1. PB | GO:0098038 | non-replicative transposition, DNA-mediated |
| 1. PB | GO:0043565 | sequence-specific DNA binding |
| 1. PB | GO:0005654 | nucleoplasm |
| 2. P | GO:0005634 | nucleus |
| 3. B | GO:0005044 | scavenger receptor activity |
| 3. B | GO:0033141 | positive regulation of peptidyl-serine phosphorylation of STAT protein |
| 3. B | GO:0010628 | positive regulation of gene expression |
| 3. B | GO:0045739 | positive regulation of DNA repair |
| 3. B | GO:0002230 | positive regulation of defense response to virus by host |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
| Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
|---|---|---|---|---|---|
| 1. PB | Q96DM1 | PiggyBac transposable element-derived protein 4 | 0 | 3.29e-141 | 0.0 |
| 1. PB | Q6P3X8 | PiggyBac transposable element-derived protein 2 | 3.58e-13 | 5.08e-46 | 1.69e-21 |
| 1. PB | Q8N328 | PiggyBac transposable element-derived protein 3 | 1.42e-13 | 7.19e-48 | 7.50e-27 |
| 1. PB | Q8N414 | PiggyBac transposable element-derived protein 5 | 2.98e-11 | 9.36e-10 | 3.44e-13 |
| 1. PB | D3YZI9 | PiggyBac transposable element-derived protein 5 | 3.07e-10 | 7.46e-08 | 6.27e-12 |
| 3. B | P0DP91 | Chimeric ERCC6-PGBD3 protein | 2.12e-11 | NA | 2.97e-26 |
| 3. B | Q96JS3 | PiggyBac transposable element-derived protein 1 | 5.35e-09 | NA | 4.39e-22 |