Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 2. P was
Q00994
(Protein BEX3) with a FATCAT P-Value: 0.0106 and RMSD of 3.30 angstrom. The sequence alignment identity is 22.1%.
Structural alignment shown in left. Query protein Q9H0H9 colored as red in alignment, homolog Q00994 colored as blue.
Query protein Q9H0H9 is also shown in right top, homolog Q00994 showed in right bottom. They are colored based on secondary structures.
Q9H0H9 ----------MVTPA--G----CLGGRNQGPREIPGTAFPCSSRAGQ-TGQAVSGAQVSSW--RERQPFGGSRGPLHILGTDGNVDTTGKLGLVPTPPR- 80 Q00994 MANIHQENEEMEQPMQNGEEDRPLGG---G--E--GHQ-P----AGNRRGQARRLAPNFRWAIPNRQINDG-------MGGDGD-DM--EIFMEEM--RE 76 Q9H0H9 IQKETKQGAL--CGMKPPFLPEALLTVWWLPFVAVS--------LCLF- 118 Q00994 IRRKLRELQLRNC-----------LRI--L-MGELSNHHDHHDEFCLMP 111
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source | GO | Description |
---|---|---|
2. P | GO:0042025 | host cell nucleus |
2. P | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity |
2. P | GO:0042622 | photoreceptor outer segment membrane |
2. P | GO:0033650 | host cell mitochondrion |
2. P | GO:0050896 | response to stimulus |
2. P | GO:0033644 | host cell membrane |
2. P | GO:0007601 | visual perception |
2. P | GO:0045745 | positive regulation of G protein-coupled receptor signaling pathway |
2. P | GO:0006919 | activation of cysteine-type endopeptidase activity involved in apoptotic process |
2. P | GO:0008625 | extrinsic apoptotic signaling pathway via death domain receptors |
2. P | GO:0039652 | induction by virus of host NF-kappaB cascade |
2. P | GO:0045742 | positive regulation of epidermal growth factor receptor signaling pathway |
2. P | GO:0039592 | suppression by virus of G2/M transition of host mitotic cell cycle |
2. P | GO:0000187 | obsolete activation of MAPK activity |
2. P | GO:0030553 | cGMP binding |
2. P | GO:0019079 | viral genome replication |
2. P | GO:0005163 | nerve growth factor receptor binding |
2. P | GO:0008656 | cysteine-type endopeptidase activator activity involved in apoptotic process |
2. P | GO:0006351 | transcription, DNA-templated |
2. P | GO:0007275 | multicellular organism development |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
---|---|---|---|---|---|
1. PB | Q9H0H9 | Putative cytochrome P450 family member 4F30 | 0 | 1.66e-160 | 1.33e-81 |
2. P | Q9PXA2 | Protein X | NA | 5.96e-03 | NA |
2. P | Q00994 | Protein BEX3 | 1.06e-02 | 2.72e-02 | NA |
2. P | Q8N814 | Putative uncharacterized protein FLJ40140 | 2.09e-01 | 5.83e-03 | NA |
2. P | P16844 | Uncharacterized protein UL15A | NA | 1.02e-02 | NA |
2. P | A6NN06 | Putative UPF0633 protein MGC21881 | 1.48e-01 | 4.09e-04 | NA |
2. P | O83168 | Uncharacterized protein TP_0132 | 1.16e-01 | 6.22e-03 | NA |
2. P | Q8TGK1 | Uncharacterized protein YHR213W-B | 6.50e-01 | 4.33e-05 | NA |
2. P | P39563 | Uncharacterized protein YAR064W | 6.57e-01 | 2.26e-05 | NA |
2. P | Q8IU53 | Protein CASC2, isoforms 1/2 | 5.57e-01 | 4.96e-02 | NA |
2. P | P17142 | Uncharacterized protein IRL3 | NA | 4.28e-04 | NA |
2. P | Q5VV11 | Putative UPF0633 protein ENSP00000303136 | 1.29e-01 | 1.60e-07 | NA |
2. P | Q8TAF5 | Putative uncharacterized protein LQK1 | 7.01e-01 | 5.42e-03 | NA |
2. P | Q8N910 | Putative uncharacterized protein PAK6-AS1 | 1.03e-01 | 2.22e-02 | NA |
2. P | Q9NZY2 | Putative uncharacterized protein FAM30A | 1.76e-01 | 1.38e-04 | NA |
2. P | Q5XG85 | Putative UPF0633 protein LOC554249 | 2.36e-01 | 1.06e-06 | NA |
2. P | F5HAE6 | Uncharacterized protein UL15A | NA | 4.87e-03 | NA |
2. P | Q8NI28 | Putative uncharacterized protein encoded by LINC01006 | 2.32e-01 | 1.39e-03 | NA |
2. P | P20977 | Protein X | NA | 1.07e-02 | NA |
2. P | P34238 | Putative uncharacterized protein YKL177W | 3.78e-01 | 3.91e-02 | NA |
2. P | P22571 | Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma | 3.23e-01 | 2.44e-02 | NA |
2. P | Q9PX75 | Protein X | NA | 4.63e-02 | NA |
2. P | Q96MZ4 | Protein FAM218A | 1.27e-01 | 1.17e-02 | NA |
2. P | Q03207 | Uncharacterized protein YML122C | 4.68e-01 | 4.32e-02 | NA |
2. P | P25603 | Putative uncharacterized protein CWH36 | 9.33e-02 | 1.16e-04 | NA |
2. P | Q5VT28 | Protein FAM27A/B/C | 5.77e-02 | 1.08e-02 | NA |