Summary

Q9H1L0

Homolog: P0DO97.
Function: Coiled-coil domain-containing protein 192.

Statistics

Total GO Annotation: 45
Unique PROST Go: 41
Unique BLAST Go: 4

Total Homologs: 31
Unique PROST Homologs: 29
Unique BLAST Homologs: 1

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was P0DO97 (Coiled-coil domain-containing protein 192) with a FATCAT P-Value: 0.0212 and RMSD of 2.96 angstrom. The sequence alignment identity is 10.1%.
Structural alignment shown in left. Query protein Q9H1L0 colored as red in alignment, homolog P0DO97 colored as blue. Query protein Q9H1L0 is also shown in right top, homolog P0DO97 showed in right bottom. They are colored based on secondary structures. 

  Q9H1L0 -MPSCSCA---------L-MAPC--GPAAGPAA--VERTQQVARGEPGSARGQLQVSPEMSITHKEKENAHLKEILLFVNAEAFSQPQPHSAPVC--E-- 81
  P0DO97 MMPVDVCPRDRGSQWVWLEMGQCYSKKSVVPESDTSERSSMTS----GSSESDI---P--------QEN-KVSKASLDTGQMAFTLAQLESLEICLKEAE 84

  Q9H1L0 ------GQQLT---G-KFSTSVL---TR-------------AGGDASPCSWERLLCYGWSHC-------------------------------------- 117
  P0DO97 EKAKALSEQLSVSEGTK--SKLLEQVSRLEEKLEAVDHKEASGG---P--YEKMVLVK-DQCIQKLQAEVKASQEQLIAQKLKHEKKVKKLQTDLATANA 176

  Q9H1L0 ---------------------------------------------------------------------------------------------------- 117
  P0DO97 ITVLELNEKIKTLYEGKPAPREDSLLEGFCGGLPPVEEGDRKISLIMELSTQVSLQTERITQLKEVLEEKERKIQQLEAERSPHPPQEVKDPPGCLPEAP 276

  Q9H1L0 ---------------- 117
  P0DO97 VFSTHDIPPVVSDENL 292

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0060392 negative regulation of SMAD protein signal transduction
2. P GO:0018342 protein prenylation
2. P GO:0098536 deuterosome
2. P GO:0018345 protein palmitoylation
2. P GO:0009651 response to salt stress
2. P GO:0045786 negative regulation of cell cycle
2. P GO:0005814 centriole
2. P GO:0007098 centrosome cycle
2. P GO:0007346 regulation of mitotic cell cycle
2. P GO:1903251 multi-ciliated epithelial cell differentiation
2. P GO:0008156 negative regulation of DNA replication
2. P GO:0031225 anchored component of membrane
2. P GO:0030010 establishment of cell polarity
2. P GO:0003009 skeletal muscle contraction
2. P GO:0030027 lamellipodium
2. P GO:0010182 sugar mediated signaling pathway
2. P GO:0005834 heterotrimeric G-protein complex
2. P GO:0042383 sarcolemma
2. P GO:0009267 cellular response to starvation
2. P GO:0007186 G protein-coupled receptor signaling pathway
2. P GO:0030030 cell projection organization
2. P GO:0006521 regulation of cellular amino acid metabolic process
2. P GO:0070652 HAUS complex
2. P GO:0006970 response to osmotic stress
2. P GO:0045098 type III intermediate filament
2. P GO:0005880 nuclear microtubule
2. P GO:0044458 motile cilium assembly
2. P GO:0048527 lateral root development
2. P GO:0009845 seed germination
2. P GO:0010540 basipetal auxin transport
2. P GO:0009901 anther dehiscence
2. P GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
2. P GO:0001222 transcription corepressor binding
2. P GO:1902017 regulation of cilium assembly
2. P GO:0030335 positive regulation of cell migration
2. P GO:0016529 sarcoplasmic reticulum
2. P GO:0098535 de novo centriole assembly involved in multi-ciliated epithelial cell differentiation
2. P GO:0098534 centriole assembly
2. P GO:0051225 spindle assembly
2. P GO:1990498 mitotic spindle microtubule
2. P GO:0071333 cellular response to glucose stimulus
3. B GO:0004252 serine-type endopeptidase activity
3. B GO:0004176 ATP-dependent peptidase activity
3. B GO:0030163 protein catabolic process
3. B GO:0006355 regulation of transcription, DNA-templated

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q9H1L0 Uncharacterized protein MIR1-1HG 0 1.41e-138 6.59e-83
2. P Q29RU3 Coiled-coil domain-containing protein 54 2.22e-01 7.86e-03 NA
2. P Q6QZQ4 Vimentin-type intermediate filament-associated coiled-coil protein 1.24e-01 1.93e-02 NA
2. P Q6ZSJ8 Uncharacterized protein C1orf122 2.16e-02 1.87e-05 NA
2. P Q5SSQ6 Suppressor APC domain-containing protein 1 2.13e-02 4.44e-04 NA
2. P Q9CY86 Suppressor APC domain-containing protein 1 2.40e-02 2.34e-02 NA
2. P A2IDD5 Coiled-coil domain-containing protein 78 3.19e-01 3.24e-02 NA
2. P A6QQF7 Protein FAM89A 1.20e-01 4.83e-02 NA
2. P B8AN27 Guanine nucleotide-binding protein subunit gamma 1 6.21e-02 4.92e-02 NA
2. P P0DO97 Coiled-coil domain-containing protein 192 2.12e-02 3.48e-03 NA
2. P Q96GI7 Protein FAM89A 8.71e-02 4.62e-02 NA
2. P Q566R4 Leucine repeat adapter protein 25 5.18e-02 5.66e-03 NA
2. P Q3UNU4 Glutamate-rich protein 4 1.26e-01 2.95e-02 NA
2. P Q08AY9 Protein FAM89A 1.14e-01 1.08e-02 NA
2. P Q9FGX2 Basic leucine zipper 1 1.19e-01 4.99e-03 NA
2. P Q8IYJ2 Uncharacterized protein C10orf67, mitochondrial 4.39e-01 1.74e-02 NA
2. P D6RGH6 Multicilin 4.93e-01 6.48e-03 NA
2. P Q2YDE5 Putative coiled-coil domain-containing protein 196 1.07e-01 1.16e-02 NA
2. P Q9QUI1 Leucine repeat adapter protein 25 8.27e-02 4.83e-02 NA
2. P Q1JPL0 Uncharacterized protein C2orf50 homolog 6.91e-02 9.60e-03 NA
2. P B1ARW8 Uncharacterized protein C1orf122 homolog 2.41e-02 1.10e-03 NA
2. P Q6Q0N2 Protein FAM89A 1.51e-01 1.81e-02 NA
2. P Q2NL98 Vimentin-type intermediate filament-associated coiled-coil protein 1.61e-01 5.04e-03 NA
2. P Q5BK57 HAUS augmin-like complex subunit 8 2.57e-01 1.98e-02 NA
2. P A1L168 Uncharacterized protein C20orf202 6.69e-03 5.19e-03 NA
2. P P0C7N2 Glutamate-rich protein 4 1.19e-01 4.18e-02 NA
2. P A7YWC8 Vimentin-type intermediate filament-associated coiled-coil protein 1.29e-01 2.52e-02 NA
2. P Q75WU1 Guanine nucleotide-binding protein subunit gamma 1 6.41e-02 4.92e-02 NA
2. P Q8NEL0 Coiled-coil domain-containing protein 54 1.89e-01 1.50e-02 NA
2. P Q93V47 Guanine nucleotide-binding protein subunit gamma 2 5.73e-02 8.65e-03 NA
3. B Q8NKS6 Archaeal Lon protease 7.40e-01 NA 0.035