Summary

Q9H4I3

Homolog: Q58DF3.
Function: TraB domain-containing protein.

Statistics

Total GO Annotation: 7
Unique PROST Go: 7
Unique BLAST Go: 0

Total Homologs: 9
Unique PROST Homologs: 5
Unique BLAST Homologs: 1

Structures and Sequence Alignment

The best structural homolog that predicted by 1. PB was Q58DF3 (TraB domain-containing protein) with a FATCAT P-Value: 0.0 and RMSD of 2.40 angstrom. The sequence alignment identity is 88.9%.
Structural alignment shown in left. Query protein Q9H4I3 colored as red in alignment, homolog Q58DF3 colored as blue. Query protein Q9H4I3 is also shown in right top, homolog Q58DF3 showed in right bottom. They are colored based on secondary structures. 

  Q9H4I3 MDGEEQQPPHEANVEPVVPSEASEPVPRVLSGDPQNLSDVDAFNLLLEMKLKRRRQRPNLPRTVTQLVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQP 100
  Q58DF3 MEEPEEQPPHEADTEPVVTSGASEAVPRVLPGDPQNLSDVDAFNLLLEMKLKRRRERPNLPHTVTELVAEDGSRVYVVGTAHFSDDSKRDVVKTIREVQP 100

  Q9H4I3 DVVVVELCQYRVSMLKMDESTLLREAQELSLEKLQQAVRQNGLMSGLMQMLLLKVSAHITEQLGMAPGGEFREAFKEASKVPFCKFHLGDRPIPVTFKRA 200
  Q58DF3 DVVVVELCQYRVSMLKMDERTLLREAKEISLEKLQQAIRQNGVASGLMQMLLLKVSAHITEQLGVAPGGEFREAFKEASRVPFCKFHLGDRPIPVTFKRA 200

  Q9H4I3 IAALSFWQKVRLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMIGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGH 300
  Q58DF3 IAALSLWQKVKLAWGLCFLSDPISKDDVERCKQKDLLEQMMAEMVGEFPDLHRTIVSERDVYLTYMLRQAARRLELPRASDAEPRKCVPSVVVGVVGMGH 300

  Q9H4I3 VPGIEKNWSTDLNIQEIMTVPPPSVSGRVSRLAVKAAFFGLLGYSLYWMGRRTASLVLSLPAAQYCLQRVTEA-RHK 376
  Q58DF3 VPGIEKNWTTDLNIQEIMTVPPPSASGRVSRLAVKAAALGLLGYGLYWTGRRAVSLLLALPAARHCLQRLSDAWPQK 377

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0046872 metal ion binding
2. P GO:0004222 metalloendopeptidase activity
2. P GO:0017147 Wnt-protein binding
2. P GO:0031301 integral component of organelle membrane
2. P GO:0030178 negative regulation of Wnt signaling pathway
2. P GO:0016055 Wnt signaling pathway
2. P GO:0016020 membrane

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q99JY4 TraB domain-containing protein 0.00e+00 5.32e-99 0.0
1. PB Q9H4I3 TraB domain-containing protein 0 8.84e-131 0.0
1. PB Q58DF3 TraB domain-containing protein 0.00e+00 1.50e-94 0.0
2. P A7RX69 Metalloprotease TIKI homolog 1.18e-02 4.48e-05 NA
2. P Q17678 Metalloprotease TIKI homolog 1.12e-01 1.79e-07 NA
2. P P77301 Uncharacterized protein YbaP 6.16e-03 8.77e-03 NA
2. P Q83M36 Uncharacterized protein YbaP 5.72e-03 5.35e-03 NA
2. P E7F4V6 Metalloprotease TIKI2 2.72e-02 1.51e-02 NA
3. B Q58760 Uncharacterized protein MJ1365 1.82e-06 NA 2.20e-13