Summary

Q9UHU1

Homolog: P68353.
Function: COP9 signalosome complex subunit 2 (Fragments).

Statistics

Total GO Annotation: 26
Unique PROST Go: 26
Unique BLAST Go: 0

Total Homologs: 16
Unique PROST Homologs: 15
Unique BLAST Homologs: 0

Structures and Sequence Alignment

The best structural homolog that predicted by 2. P was P68353 (COP9 signalosome complex subunit 2 (Fragments)) with a FATCAT P-Value: 1.07e-10 and RMSD of 0.49 angstrom. The sequence alignment identity is 19.2%.
Structural alignment shown in left. Query protein Q9UHU1 colored as red in alignment, homolog P68353 colored as blue. Query protein Q9UHU1 is also shown in right top, homolog P68353 showed in right bottom. They are colored based on secondary structures. 

  Q9UHU1 MLTALGQVNNIQKEFTIKKT------KQADH--NLVARIDEIQYVQGTINL- 43
  P68353 -------KSAVTRNYSEKKNERLWFKKNYDHAGN-QRRIQ--KW--NT-QLK 39

Go Annotations

1. PB indicates the go terms that are found by both PROST and BLAST.
2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source GO Description
2. P GO:0008180 COP9 signalosome
2. P GO:1901877 negative regulation of calcium ion binding
2. P GO:1901895 negative regulation of ATPase-coupled calcium transmembrane transporter activity
2. P GO:0007015 actin filament organization
2. P GO:0003989 acetyl-CoA carboxylase activity
2. P GO:0005096 GTPase activator activity
2. P GO:0019076 viral release from host cell
2. P GO:0033017 sarcoplasmic reticulum membrane
2. P GO:0033644 host cell membrane
2. P GO:0005576 extracellular region
2. P GO:0009585 red, far-red light phototransduction
2. P GO:0004857 enzyme inhibitor activity
2. P GO:0032801 receptor catabolic process
2. P GO:0030435 sporulation resulting in formation of a cellular spore
2. P GO:0043087 regulation of GTPase activity
2. P GO:2001295 malonyl-CoA biosynthetic process
2. P GO:1902081 negative regulation of calcium ion import into sarcoplasmic reticulum
2. P GO:0005261 cation channel activity
2. P GO:0042601 endospore-forming forespore
2. P GO:0006119 oxidative phosphorylation
2. P GO:0019835 cytolysis
2. P GO:0042742 defense response to bacterium
2. P GO:0009611 response to wounding
2. P GO:0045277 respiratory chain complex IV
2. P GO:0042609 CD4 receptor binding
2. P GO:0030436 asexual sporulation

Homologs

1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.

Source Homolog Description FATCAT p-val PROST Evalue BLAST Evalue
1. PB Q9UHU1 Putative uncharacterized protein PRO1716 0 4.04e-144 1.30e-24
2. P P24034 Protein Vpw NA 1.41e-03 NA
2. P O57414 Rho GTPase-activating protein 6 (Fragment) 8.92e-03 7.68e-03 NA
2. P P80976 Cytochrome c oxidase subunit 6B (Fragments) 6.64e-02 7.46e-03 NA
2. P Q9CV60 Myoregulin 2.35e-04 2.35e-04 NA
2. P P85438 Acetyl-CoA carboxylase (Fragments) NA 4.68e-02 NA
2. P P08804 Protein Vpu (Fragment) NA 4.11e-03 NA
2. P E8RUP8 Astexin-3 NA 3.50e-02 NA
2. P A7Z570 Small, acid-soluble spore protein N 8.97e-01 3.34e-02 NA
2. P P0C8X1 Peptide 9797 (Fragment) 1.19e-03 2.54e-02 NA
2. P A0A6M3Z554 U11-myrmicitoxin-Tb1a (Fragment) 2.53e-06 6.76e-03 NA
2. P P68353 COP9 signalosome complex subunit 2 (Fragments) 1.07e-10 5.02e-03 NA
2. P H7C8I3 Lariatin NA 2.82e-02 NA
2. P P49975 50S ribosomal protein L15 (Fragment) 1.50e-01 2.02e-02 NA
2. P P56651 Inter-alpha-trypsin inhibitor heavy chain H2 (Fragments) 6.22e-01 7.65e-04 NA
2. P P59866 Non-cysteinic peptide Bs 10 8.84e-01 1.09e-03 NA