Summary
Structures and Sequence Alignment
The best structural homolog that predicted by 1. PB was
Q7YR46
(Psoriasis susceptibility 1 candidate gene 1 protein homolog) with a FATCAT P-Value: 0.00336 and RMSD of 4.00 angstrom. The sequence alignment identity is 96.1%.
Structural alignment shown in left. Query protein Q9UIG5 colored as red in alignment, homolog Q7YR46 colored as blue.
Query protein Q9UIG5 is also shown in right top, homolog Q7YR46 showed in right bottom. They are colored based on secondary structures.
Q9UIG5 MTCTDQKSHSQRALGTQTPALQGPQLLNTDPSSEETRPPHVNPDRLCHMEPANHFWHAGDLQAMISKEFHLAATQDDCRKGRTQEDILVPSSHPELFASV 100 Q7YR46 MTCTDQKSHSQRALGTQTPALQGPQLLNTDPSSEETRPPHVYPDRLCHMEPANHFWHAGDLQAMTSKEFHLAATQDDCRKGRTQEDILVPSSHPELFSSV 100 Q9UIG5 LPMAPEEAARLQQPQPLPPPSGIHLSASRTLAPTLLYSSPPSHSPFGLSSLI 152 Q7YR46 LPMALEEAARLQQPQPLPPPSGIHLSASRTSAPTLLYSPPPSHSPFGLSSLI 152
Go Annotations
1. PB indicates the go terms that are found by both PROST and BLAST.2. P indicates the go terms that are found by only PROST.
3. B indicates the go terms that are only annotated by BLAST.
Source | GO | Description |
---|---|---|
2. P | GO:0017124 | SH3 domain binding |
2. P | GO:2000816 | negative regulation of mitotic sister chromatid separation |
2. P | GO:0051276 | chromosome organization |
2. P | GO:0045143 | homologous chromosome segregation |
Homologs
1. PB indicates the homologs that are found by both PROST and BLAST.
2. P indicates homologs that are only found by PROST.
3. B indicates homologs that are only found by BLAST.
Source | Homolog | Description | FATCAT p-val | PROST Evalue | BLAST Evalue |
---|---|---|---|---|---|
1. PB | Q9UIG5 | Psoriasis susceptibility 1 candidate gene 1 protein | 0 | 1.03e-125 | 3.04e-108 |
1. PB | Q7YR46 | Psoriasis susceptibility 1 candidate gene 1 protein homolog | 3.36e-03 | 1.32e-51 | 1.51e-102 |
2. P | Q9BDP6 | Securin (Fragment) | 2.17e-01 | 2.54e-02 | NA |