Summary
NP_009706.3
Homolog: XP_453931.1.
Wiesman et al.[1]: NCAS0I02430 (S. cast) | KLLA0C03784g (K. lac) | AFR604C (A. gos) | Kwal_56.22618 (K. wal)
Statistics
Total Homologs: 17
Non significant structural homologs: 1
Total Synteny Homologs: 4
Found Synteny Homologs: 4
Synteny Status: Synteny homolog(s) found
Structures and Sequence Alignment
The best structural homolog was
XP_453931.1
(XP_453931.1 uncharacterized protein KLLA0_D19580g [Kluyveromyces lactis]) with a FATCAT [2] P-Value: 2.93e-04 and RMSD of 4.63 angstrom. The sequence alignment identity is 23.8%.
Structural alignment shown in left. Query protein NP_009706.3 colored as red in alignment, homolog XP_453931.1 colored as blue.
Query protein NP_009706.3 is also shown in right top, homolog XP_453931.1 showed in right bottom. They are colored based on secondary structures.
NP_009706.3 ----------------------------------------------MSSLADTVEG-----SEA----K-RG--------RFSN-NALTSDT---GILQK 32 XP_453931.1 MLSPTGKRRGSFIGNQTDAKQEEKFDYTDSEFDLTVDKQSSQSPLKFHDFMDRLVGKNKLLAQAEQYDKARGVIIPKNDSSFENENNV-QDSKSEGRVQV 99 NP_009706.3 NSTLRNWFLKPTADLKNSCEDRV-EDDVNDV-Y--LN------DKNSQ----------K--SVEERKLGRKV-RSFFKQTNSN-KDESVLEDEDDALVWK 108 XP_453931.1 DSPI----LKE-QDLNKASESNLSERRITSVEYPKLNKQMQFHDSAAQVSAMPYMPNPKGTTIEEHLLVQSTPLSKIKQHNVNGKNSSTSQPKD--LLKE 192 NP_009706.3 KTSNKCAKKE--NSHD------IQKGSFTKKIRNSI--FKSAND-VKEFRNENNLLLPVELSSDDENESH---------FTD-ANSHVMQSK----SPEK 183 XP_453931.1 KFQD--SRKQSLNDHDPPTTTEL-K---TTELRDELTKFKEELDGINRVRNEQEQELRV-L-KDSSNKKDKELAQLKREYNDLINS-VDEAKIRAQKTEK 283 NP_009706.3 -IPSKDQCLT----KGAKN-----KGLK------KE-----YEK-SFEEYSDDSDDEFSPATPPENVLEGPYKFVFQTPNTFTS--------QPNIT--- 250 XP_453931.1 EFQTKIQNLTDELLKKEKSHTVTVKKLKAELKSTKELQAGLVEKASMQKLQEDMEERL-------NSLSDVVKSRDSTINDLTAKLKSADAEQEQLSLQL 376 NP_009706.3 VENDFHKGGRHVIDYLNKKLA---TMNIDI-DL-----TSGGKQNVSWEEELDQLSDHVI------ESITNHISKGRMHAQE------KQDELEKLKLEN 329 XP_453931.1 LES------KTLVEQLNSKLESKLTVEAEVSDLKSKLATANNENSV----LLQYIANFTLFKVKVGEFLISQI--GRKKSQETCEKWLKSQHIIGYKTEN 464 NP_009706.3 -------L-NL------STL--KQENLQH-KQEI---NS----LKDNLESISKKNNDLI-LEMNKLKKKSTNNKTN----EYISTDENENEEITKSNMGP 400 XP_453931.1 EEESFTSLKNLVERDLKPTLEEKSSRISYLEKEVGDKNSKITELLDKVTDVQQSREELISLR-DQLTSEVTSLKSQICSSE-ITAKENAFKDLTEQNL-- 560 NP_009706.3 GILE-LN-VNE---T--SK-KLQQSTFKPSKYLPRETRNNENRLKHLEKRIFGLEKSLEKKKKQVRADSVRLDLNRYTIDQFLTLLKSLSEVLQFH-N-- 489 XP_453931.1 KLLEKMNVVNDEVATILMKLKTESASLQKEKEL---SANMKSTISHLESSLSKIRKSYEKVKGNA-ADKI-------TPD---TLMK-----IHTHMNKE 641 NP_009706.3 VYGN-DLKEND--DNIIKIETCCSALN-MKN--CFEDSSF-RLQENSFKRQLGPLFANINFSL-IDQLTMNFRFYERSANFQKETIGGLRMMLQDKDNYI 581 XP_453931.1 SYENLEL---DTIDNLNLVE--CQ--NTIKNIVAILDISYSKL---SSK--L-PL---VNIMLRYEK-TMLFHF----AN--K--VHNL-LFHQEID--F 713 NP_009706.3 KT-----LMQ---HLKKKE-STKL---IKD-SKN-GASTLTS 609 XP_453931.1 KTFTKKALENYWTHRNAKEIQHPLEQCLKDLYKSVSEKLLV- 754
Homologs
| Homolog | Description | FATCAT p-val | FATCAT RMSD | PROST Evalue | Synteny | Sequence Identity |
|---|---|---|---|---|---|---|
| XP_003678253.1 | XP_003678253.1 hypothetical protein NCAS_0I02430 [Naumovozyma castellii CBS 4309] | 2.89e-03 | 9.99 | 1.09e-16 | True | 26.86% |
| XP_003673807.1 | XP_003673807.1 hypothetical protein NCAS_0A08680 [Naumovozyma castellii CBS 4309] | 8.53e-04 | 9.78 | 1.85e-13 | False | 27.04% |
| Kwal_22618 | Kwal_22618 | 9.76e-03 | 11.09 | 9.38e-12 | True | 23.41% |
| XP_452365.1 | XP_452365.1 uncharacterized protein KLLA0_C03784g [Kluyveromyces lactis] | 1.19e-03 | 10.06 | 2.27e-11 | True | 25.68% |
| AFR604C | AFR604C | 1.72e-03 | 7.17 | 4.40e-07 | True | 20.90% |
| NP_986151.2 | NP_986151.2 AFR604Cp [Eremothecium gossypii ATCC 10895] | 1.54e-02 | 12.03 | 6.62e-07 | False | 20.81% |
| XP_003673689.1 | XP_003673689.1 hypothetical protein NCAS_0A07500 [Naumovozyma castellii CBS 4309] | 2.90e-02 | 14.82 | 1.08e-06 | False | 22.47% |
| XP_659028.1 | XP_659028.1 hypothetical protein AN1424.2 [Aspergillus nidulans FGSC A4] | 1.80e-03 | 7.88 | 1.18e-05 | False | 22.78% |
| XP_505313.1 | XP_505313.1 YALI0F12023p [Yarrowia lipolytica CLIB122] | 6.62e-03 | 6.91 | 1.27e-05 | False | 16.17% |
| XP_454845.1 | XP_454845.1 uncharacterized protein KLLA0_E19757g [Kluyveromyces lactis] | 2.88e-03 | 5.20 | 1.51e-05 | False | 20.66% |
| Kwal_11131 | Kwal_11131 | 4.35e-02 | 9.49 | 2.22e-05 | False | 23.01% |
| XP_502977.1 | XP_502977.1 YALI0D18249p [Yarrowia lipolytica CLIB122] | 3.48e-03 | 12.87 | 3.76e-05 | False | 21.36% |
| XP_003675959.1 | XP_003675959.1 hypothetical protein NCAS_0D00140 [Naumovozyma castellii CBS 4309] | 4.69e-03 | 5.35 | 2.78e-04 | False | 24.63% |
| XP_455759.1 | XP_455759.1 uncharacterized protein KLLA0_F15136g [Kluyveromyces lactis] | 5.74e-02 | 8.31 | 5.47e-04 | False | 23.94% |
| XP_453931.1 | XP_453931.1 uncharacterized protein KLLA0_D19580g [Kluyveromyces lactis] | 2.93e-04 | 4.63 | 5.52e-04 | False | 23.61% |
| XP_658817.1 | XP_658817.1 hypothetical protein AN1213.2 [Aspergillus nidulans FGSC A4] | 1.71e-02 | 11.61 | 7.32e-04 | False | 15.23% |
| NP_982754.2 | NP_982754.2 ABL193Cp [Eremothecium gossypii ATCC 10895] | 2.55e-02 | 14.18 | 8.20e-04 | False | 22.29% |