Summary

NP_012497.3

Homolog: XP_003676781.1.
Wiesman et al.[1]:

Statistics

Total Homologs: 5
Non significant structural homologs: 0
Total Synteny Homologs: 0
Found Synteny Homologs: 0
Synteny Status: No synteny homologs exists

Structures and Sequence Alignment

The best structural homolog was XP_003676781.1 (XP_003676781.1 hypothetical protein NCAS_0E03540 [Naumovozyma castellii CBS 4309]) with a FATCAT [2] P-Value: 7.43e-09 and RMSD of 2.20 angstrom. The sequence alignment identity is 24.9%.
Structural alignment shown in left. Query protein NP_012497.3 colored as red in alignment, homolog XP_003676781.1 colored as blue. Query protein NP_012497.3 is also shown in right top, homolog XP_003676781.1 showed in right bottom. They are colored based on secondary structures.

     NP_012497.3 MKVQMIER--IFLIQLCLLTVVLAS---S--RAVVEFES-TGTKLV-----NS-LRVL-AAYSQSSVCVDEKIS--GIERQIEEVKDMYGNH-------S 76
  XP_003676781.1 ----MLFRTSTFAI-FFLLTATITSLVGSIWRS--DFDRVSG-KLMEMYEANTCARFLQGGYSTDSL-VDAQSSFNSLNQQLRDVKEKYSKQPAYLEVLS 91

     NP_012497.3 FIL----KGLNGI--LNNK--VNM--LTREIQMETVGNNTFETETG---KL-TKGLNRAVNISPFKYIKKFKTVS--T-KKFESLLNKYDLVAK-KGGEL 158
  XP_003676781.1 MVLKIKVKAFEGISPLRRSAAVDMKLLSRALSFALEFNPDSDADDGYSFKIRNQGVK---NDGPAD-IQVAHTLASLTENNFQAADN--DPVSRFEG--- 182

     NP_012497.3 TEEQKKKKEVLSRISRVVAATTIE-AGLAQGVVDLCITVTTSLCLVSASIGGVGFLIWLTIIYQALT---------- 224
  XP_003676781.1 ---HKK----LYQ----EGAKTFEFMALIFGA---CIGLPGIMCQL-FMIFGVGQLVRF-FIH--LIKFSFDLEIHP 241

Homologs

Homolog Description FATCAT p-val FATCAT RMSD PROST Evalue Synteny Sequence Identity
Kwal_1573 Kwal_1573 5.13e-07 2.36 2.70e-18 False 23.79%
XP_003676770.1 XP_003676770.1 hypothetical protein NCAS_0E03430 [Naumovozyma castellii CBS 4309] 6.20e-07 2.92 1.07e-06 False 25.00%
XP_003676781.1 XP_003676781.1 hypothetical protein NCAS_0E03540 [Naumovozyma castellii CBS 4309] 7.43e-09 2.20 1.44e-05 False 23.91%
XP_003673454.1 XP_003673454.1 hypothetical protein NCAS_0A05100 [Naumovozyma castellii CBS 4309] 9.67e-06 2.21 7.05e-04 False 23.56%
XP_003673495.1 XP_003673495.1 hypothetical protein NCAS_0A05540 [Naumovozyma castellii CBS 4309] 2.58e-04 3.33 7.64e-04 False 23.56%