Summary

NP_015396.1

Homolog: NP_593198.1.
Wiesman et al.[1]:

Statistics

Total Homologs: 28
Non significant structural homologs: 1
Total Synteny Homologs: 0
Found Synteny Homologs: 0
Synteny Status: No synteny homologs exists

Structures and Sequence Alignment

The best structural homolog was NP_593198.1 (NP_593198.1 protein meu31 [Schizosaccharomyces pombe]) with a FATCAT [2] P-Value: 6.25e-06 and RMSD of 2.64 angstrom. The sequence alignment identity is 18.5%.
Structural alignment shown in left. Query protein NP_015396.1 colored as red in alignment, homolog NP_593198.1 colored as blue. Query protein NP_015396.1 is also shown in right top, homolog NP_593198.1 showed in right bottom. They are colored based on secondary structures.

  NP_015396.1 MQNGTEDKSNIPARSNDDVLPPLAVRLTMKVMRLIF-IGKMFAYS--FVPFPPFKLLTFDNTVG--WFVAYSAI-----VSIWG-----------FAVWM 79
  NP_593198.1 -------------------------------MSCISEIGK-FVKSIEYIKLP--CLFIFAAIVGMNLSLLYCLLKGWKNVMIWGIETMLFGAIGIFFAWK 66

  NP_015396.1 ER-GYRHKINLL-------PPRCTKIR-CS----------RC---NTR--IR-SPNWFKYKNWLYFFLLYVSLTTSNL--IIQLASFMTEMSRRGISV-P 151
  NP_593198.1 KKLSWEH-LVLLWSTIDAFFSMC--LRSCTIIYFSMNPYMLCEILNARNVISCSLNTQK-----FFFII---VAASNVYSIFQLCGCLL-MFNNIISIRP 154

  NP_015396.1 G--TKDPG-KRDYL--GLI------IPMRFIGAFIHYMTANLFKEYYLHNGPLEKNDRPSTDEKTSENETL 211
  NP_593198.1 SERT-EPEFNFD-LEKGVAFASDSEFPEKSICI-------------------------------------- 185

Homologs

Homolog Description FATCAT p-val FATCAT RMSD PROST Evalue Synteny Sequence Identity
XP_003677323.1 XP_003677323.1 hypothetical protein NCAS_0G00830 [Naumovozyma castellii CBS 4309] 1.23e-05 3.16 4.10e-23 False 22.13%
XP_003677322.1 XP_003677322.1 hypothetical protein NCAS_0G00820 [Naumovozyma castellii CBS 4309] 4.46e-05 2.96 1.01e-20 False 23.17%
NP_986299.1 NP_986299.1 AGL367Cp [Eremothecium gossypii ATCC 10895] 3.36e-04 2.78 7.25e-11 False 17.96%
Kwal_22007 Kwal_22007 4.08e-05 3.02 1.66e-08 False 17.74%
XP_663863.1 XP_663863.1 predicted protein [Aspergillus nidulans FGSC A4] 2.27e-04 3.49 2.42e-08 False 20.08%
XP_501620.2 XP_501620.2 YALI0C08921p [Yarrowia lipolytica CLIB122] 7.10e-05 2.07 4.20e-08 False 20.36%
XP_455628.1 XP_455628.1 uncharacterized protein KLLA0_F12078g [Kluyveromyces lactis] 1.56e-05 1.04 5.65e-08 False 18.38%
NP_593198.1 NP_593198.1 protein meu31 [Schizosaccharomyces pombe] 6.25e-06 2.64 2.19e-07 False 18.82%
XP_003675807.1 XP_003675807.1 hypothetical protein NCAS_0C04530 [Naumovozyma castellii CBS 4309] 4.78e-05 3.27 2.70e-07 False 23.05%
XP_505211.2 XP_505211.2 YALI0F09515p [Yarrowia lipolytica CLIB122] 1.83e-01 2.91 4.07e-07 False 19.58%
XP_660052.1 XP_660052.1 predicted protein [Aspergillus nidulans FGSC A4] 1.86e-04 2.87 1.67e-06 False 19.54%
NP_983114.2 NP_983114.2 ABR166Cp [Eremothecium gossypii ATCC 10895] 3.37e-04 3.48 4.10e-06 False 16.93%
NP_982810.1 NP_982810.1 ABL137Wp [Eremothecium gossypii ATCC 10895] 1.18e-04 2.28 5.03e-06 False 20.73%
NP_985316.1 NP_985316.1 AFL234Cp [Eremothecium gossypii ATCC 10895] 1.35e-04 2.45 6.65e-06 False 17.42%
XP_503524.1 XP_503524.1 YALI0E04026p [Yarrowia lipolytica CLIB122] 2.34e-02 2.94 6.65e-06 False 18.73%
XP_003676929.1 XP_003676929.1 hypothetical protein NCAS_0F00890 [Naumovozyma castellii CBS 4309] 9.62e-04 2.40 7.56e-06 False 23.43%
Kwal_20009 Kwal_20009 2.04e-04 3.12 1.22e-05 False 20.07%
NP_595470.1 NP_595470.1 secretory component protein [Schizosaccharomyces pombe] 7.64e-05 2.71 4.74e-05 False 20.62%
XP_003674090.1 XP_003674090.1 hypothetical protein NCAS_0A11510 [Naumovozyma castellii CBS 4309] 1.32e-03 3.00 5.81e-05 False 18.29%
NP_593290.1 NP_593290.1 putative COPI-coated vesicle-associated protein [Schizosaccharomyces pombe] 1.66e-03 4.06 8.53e-05 False 18.18%
NP_592907.2 NP_592907.2 putative protein Vps55 [Schizosaccharomyces pombe] 5.10e-05 2.46 1.69e-04 False 13.62%
XP_003677694.1 XP_003677694.1 hypothetical protein NCAS_0H00330 [Naumovozyma castellii CBS 4309] 1.42e-03 3.18 1.81e-04 False 22.87%
XP_454283.1 XP_454283.1 uncharacterized protein KLLA0_E07415g [Kluyveromyces lactis] 7.11e-05 2.96 2.41e-04 False 21.34%
NP_986772.1 NP_986772.1 AGR106Cp [Eremothecium gossypii ATCC 10895] 1.96e-04 3.15 2.58e-04 False 14.91%
XP_453431.1 XP_453431.1 uncharacterized protein KLLA0_D08283g [Kluyveromyces lactis] 6.47e-05 2.57 3.55e-04 False 22.95%
Kwal_14457 Kwal_14457 7.02e-05 2.37 4.03e-04 False 21.91%
NP_595217.1 NP_595217.1 Fhn1 plasma membrane organization protein [Schizosaccharomyces pombe] 1.65e-04 2.60 4.39e-04 False 17.36%
XP_503191.1 XP_503191.1 YALI0D23441p [Yarrowia lipolytica CLIB122] 3.42e-04 2.11 9.64e-04 False 20.99%